Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Dolomite and Emerald BioSystems collaborate to produce award winning novel protein crystallography instrument

Microcapillary Protein Crystallization System.jpgDolomite, a world leader in microfluidic design and manufacture, is delighted to announce its collaboration with Emerald BioSystems in the development of the Microcapillary Protein Crystallization System (MPCS) Plug MakerTM. The Plug Maker has just won a coveted "New Product Award" at LabAutomation 2010 (Palm Springs, CA). This novel touchscreen instrument enables low-volume crystallization (5-10 nL protein/experiment), for the production of diffraction-ready crystals with no wasted protein. The MPCS Plug Maker is ideal for applications such as ligand screening, hybrid screening and microfluidic seeding. The Plug Maker is a self-contained unit operated from a built-in touchscreen control unit, taking up less than two feet of bench width. 

Dolomite carried out all elements of the Plug Maker system design and development (including concept generation, industrial design, hardware and software engineering, and manufacture), creating an easy-to-use system based on Emerald's core science.  The Plug Maker automates well-validated Emerald technology, rapidly creating a series of 10nl plugs of protein and precipitant samples in a plastic CrystalCard, which are then allowed to crystallize. This revolutionary performance was made possible using Dolomite's ultra-smooth pump technology, coupled with its world-beating expertise in microfluidics and engineering. Dolomite added further value by completing the entire instrument design (including a vision system, fully automated liquid handling system and touchscreen control software). The development took just 18 months from first concept to launch at LabAutomation. 

Fine gradient optimization and sparse matrix screening can be performed simultaneously to identify optimal crystallization growth conditions. Experimental conditions are easily optimized with the ability to form on-chip gradients, with only 22 µl of protein needed. In addition, the ability to perform up to 800 experiments per chip maximizes throughput for a highly efficient workflow. 

Lance Stewart, CEO, Emerald BioSystems commented, "Dolomite has delivered a world-class product in the Plug Maker. Using Dolomite's microfluidic expertise, we have rapidly been able to take the product from initial concept and proof of principle to full instrument manufacture." Dolomite is subsequently supplying manufactured units solely to Emerald BioSystems and has agreed to collaborate with them on any further developments to the instrument. 

For further information on the MPCS Plug Maker, please visit www.emeraldbiosystems.com, or for details on the complete range of microfluidic products available from Dolomite, including chips, connectors/interconnects, pumps, valves and flow sensors, please visit www.dolomite-microfluidics.com


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events