Monthly Newsletter

As a world leader in microfluidic design, Dolomite is dedicated to providing highly optimised equipment for a range of microfluidic applications. The recently launched Mitos P-Pump provides a pulseless liquid flow, using a precise pressure driven pumping mechanism. With excellent response time and accuracy, this pressure driven flow is ideal for microfluidic systems where a highly stable flow is required. This includes applications such as compartmentalised chemistry and alginate polymerisation, which necessitate the stable formation of oil-in-water or water-in-oil droplets; however their monodispersity (size consistency) is key to obtaining accurate and repeatable results.

Dolomite has therefore carried out a number of tests to compare the size consistency of droplets formed by the Mitos P-Pump with market leading syringe pumps. Droplets of water-in-oil were generated on a 100µm sized X-Junction, using each of the pump technologies. The droplet diameter from a continuous stream was measured using image analysis software. The resulting data demonstrated that the Mitos P-Pump provides a coefficient of variation in the droplet diameter of less than 0.6%, compared with 5.5% for the leading syringe pump. Its precise pressure-driven pumping mechanism delivers liquid with a smooth and even flow, whereas even the best motor drives and mechanics of a syringe pump have slight non-linearities, which cause unwanted pulsation. The Mitos P-Pump technology therefore provides the best solution for droplet formation applications.

To download the complete study, and for further information on the Mitos P-Pump as well as Dolomite's portfolio of microfluidic products, including chips, connectors/interconnects, pumps, valves and flow sensors, please visit www.dolomite-microfluidics.com.