Thermo Fisher Scientific has developed a
high-throughput method for the simultaneous analysis of water-soluble
vitamins (WSVs) in multivitamin supplements and vitamin-enriched beverages.
The ultrahigh-performance liquid
chromatography tandem mass
spectrometry (UHPLC-MS/MS) method described in Application Note 294:
Simultaneous
Analysis of Water-Soluble Vitamins in Vitamin-Enriched Beverages and
Multivitamin Dietary Supplements by UHPLC-MS/MS was optimized for
total resolution of all target analytes on a reversed-phase
(RP) C30 column with a rapid separation LC
(RSLC) system and a triple
stage quadrupole mass spectrometer. Accurate quantitative measurements for
vitamins are required to ensure product quality and regulatory compliance as
well as to monitor vitamin intake.
This method demonstrated excellent, precision,
accuracy, and selective and sensitive detection with low quantitation limits
and a high correlation of determination, and was successfully applied to the
determination of WSVs in beverages and supplement tablets.
This application note and many others can be
found at
www.thermoscientific.com/dionex
under the
Documents
tab.
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