Oxford
Gene Technology (OGT), provider
of innovative clinical genetics and diagnostic solutions to advance
molecular medicine, has today announced the release of its next generation
targeted sequencing service. With an emphasis on flexibility, expert project design
and advanced data analysis, the new offering takes advantage of OGT's high-quality
processes and in-house bioinformatics experience to provide the most complete targeted
sequencing solution available. This includes whole exome sequencing, as well as
custom targeted sequencing of any genomic region of interest. OGT adds value at
every stage of a project, from initial experiment design through to providing
clear results. This new service makes it easy for all researchers to obtain the
benefits of next generation sequencing (NGS), without the need for extensive technical
knowledge, equipment or bioinformatics resource. By combining OGT's microarray
capabilities and sequencing offering, OGT's Genefficiency
TM Genomic Services now
offer the most complete genomic research solution available.
OGT's Chief Executive Officer, Dr Mike
Evans, commented: "We are
very excited to add targeted sequencing to our established Genefficiency brand
of genomic services. By going beyond the basic analysis routinely produced by
most sequencing platforms and service providers, our new offering delivers clear, prioritised results that researchers
can use immediately, without having to wade through vast numbers of raw sequence
files. The availability of our custom targeted sequencing service further expands
the possibilities available, allowing us to work with our clients to design the
best approach to meet their specific needs."
The planning of an NGS
experiment is a complex process, with many critical components to consider
including protocol choice, library design, capture method, instrumentation and
coverage. Optimisation of these steps is essential for generating accurate,
insightful data. As a world leading provider of genomic services, OGT's
expertise and dedication to quality control at every stage helps to ensure that
each study yields meaningful, reliable results. At the centre of this approach
is a commitment to understanding the specific project goals and delivering the
optimal solution for successful results. This includes whole exome sequencing,
as well as custom approaches using computationally
enhanced capture probes designed to a user's specification by OGT
experts.
The
average NGS experiment generates several hundred megabases of sequence, which
can be a serious obstacle to researchers in terms of data management, storage
and analysis. To meet this challenge, OGT's in-house bioinformatics team
perform all the standard alignment and quality control processing that maximises
data quality, as well as additional intelligent filtering of the information, a
feature unique to OGT's Genefficiency service. OGT's entry offering provides
results as a user-friendly HTML report that places features such as insertions,
deletions and single nucleotide polymorphisms into context.
This
includes the identification of affected genes and proteins, possible disease
associations and links to external databases. OGT's ‘advanced' and ‘expert'
services provide an even greater depth of analysis, for instance multi-genome
comparison; the exclusion of variants from a baseline genome; identification of
variants shared by all affected samples; and bespoke meta- or focused-analysis.
For
more information about OGT's new Genefficiency
sequencing services visit
www.ogt.co.uk/gsOverview.asp.
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.