Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Sartobind Pico 0.08 ml Capsule Size Completes Portfolio of Salt-Tolerant Membrane Adsorbers

Sartorius Sartobind®Polishing in antibody production is usually performed on quaternary ammonium (Q) membranes in flow-through mode, since the overall speed and productivity is much higher than on traditional anion-exchange columns. However, the binding capacity of Q ligands is reduced at higher conductivities, so concentrated feed streams must be diluted to adequately remove contaminants such as DNA, host cell proteins, viruses and endotoxins.

Sartobind STIC PA (primary amine) anion-exchange membrane overcomes this limitation and binds contaminants at high conductivities under high-salt conditions at up to 20 mS/cm. The salt-tolerant anion exchanger can directly process cation-exchange pools without further dilution. Buffer consumption and buffer tank investments can be reduced.

Sartobind pico with 0.08 ml is the latest member of the Sartobind STIC family with nano, 5", 10", 30" and mega capsules. Since all devices are used for flow-through polishing, a 4 mm bed height is kept constant to scale to larger devices up to 1.6 liters. The small membrane volume of 0.08 ml reduces material consumption during testing and virus spiking studies to save cost during the initial development phases.

All membrane adsorber capsules are "plug and play" devices and can be used like filters. As the materials are disposed of after a single use, this saves validation costs.

For further information click here


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events