Lab Bulletin

Genevac, world leaders in solvent removal technology, has over 20 year’s experience of supplying evaporators for removal of solvents from oil, fat and fuel samples.

Thermo Fisher Scientific has released a technical note (TN) that challenges the common misconception that there is significant variation in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) peak area response of oligosaccharides.

TN 133: HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides summarizes the peer-reviewed scientific literature concerning this subject. This review concludes that the variation in HPAE-PAD oligosaccharide response with structure is minimal, especially among sets of similar oligosaccharides such as those found on many glycoproteins.....

In this new application note, Millipore describes how a Novel RNA detection reagent enables gene expression analysis in living cells.

This technology allows for carrier- free cellular endocytosis of the reagent, followed by detection and relative quantitative analysis of RNA levels. Because the reagent leaves the cell after the detection event, the same sample can be used for any downstream analysis, meaning you can assess multiple biomarkers or downstream functionalities in the same cells. Additionally, this reagent requires no upfront sample preparation, has no toxic effects on cellular fate and no known nonspecific, off-target effects....

Researchers at the University Medical Center (UMC) Utrecht, the Netherlands, have identified a novel gene mutation that predisposes to seminoma, the most common form of testicular cancer in young men

The newly identified mutation, in the LRRC50 gene, can be considered as a new risk factor for testicular cancer and may be useful for screening purposes. The finding was published this week in PLoS Genetics. In preclinical research in zebrafish, it was found that mutation in the LRRC50 gene predisposes to testicular tumor formation and that zebrafish LRRC50 tumors are similar to human seminoma. These unique findings make zebrafish a useful animal model for human seminoma associated with mutation of the LRRC50 gene...

Metrohm publishes 9 new Application Notes (ANs) on near-infrared analysis of various matrices for key-information (qualitative and quantitative)

RSA (Reduced Surface Activity) Glass vials are produced by a revolutionary new patent pending production process that virtually eliminates all silanols and produces glass which has a greatly reduced surface activity for basic compounds

Thermo Fisher Scientific has developed an efficient high-performance liquid chromatography (HPLC) method for the sensitive determination of nine phenylurea compounds in drinking water and commercial bottled beverages with method detection limits that meet those reported in U.S. Environmental Protection Agency Method 532 and concentration limits set in the European Commission’s Council Directive 98/83/EC

Application Note (AN) 1046: Determination of Phenylurea Compounds in Tap Water and Bottled Green Tea demonstrates that use of on-line solid-phase extraction(SPE) and ultraviolet detection eliminates the need for expensive and time-consuming off-line SPE. Phenylurea compounds are widely used as agricultural pesticides. Due to their slow degradation, they are frequently detected in surface waters at concentrations above 0.1 μg/L, which is higher than the European Commission’s drinking water limit often used as a quality standard for natural water...

A new white paper, available from AMSBIO, discusses the latest developments in extracellular matrix (ECM) and the opportunities they offer in cancer research