184 Milton Park
Abingdon
OX14 4SE
United Kingdom
Tel: 00 44 (0) 1235 828 2
Visit Websitewww.amsbio.com
Emailinfo@amsbio.com
ContactSales amsbio - AMS Biotechnology (Europe) Ltd is the global supplier of research products and custom services for biological and pharmaceutical research. We offer antibodies, peptides, DNA, RNA, proteins, tissue blocks, arrays, slides, assay kits, cell culture consumables, glycobiology reagents, apoptosis and DNA damage kits, reagents, cell migration, invasion assays, pre-cast gels , zymolyase. AMS Biotechnology (Europe) Ltd your source for life science products and services. We have over 240,000 products in our catalogue.
Products
Antibodies
Peptides
DNA
RNA
Proteins
Tissue Blocks
Arrays
Slides
Assay kits
Cell Culture Consumables
Glycobiology Reagents
Apoptosis and DNA damage kits
Reagents
Cell Migration
Invasion Assays
Pre-cast gels
Zymolyase
Contact AMS Biotechnology (Europe) Ltd
Request further information.
Note: Your message will be sent directly to the supplier
Drawing upon a wealth of experience of working with a wide range of 3D cell culture procedures and formats the guide is aimed at assisting research scientists looking to culture cells in more physiologically relevant environments. Traditional monolayer cell culture on plastic dishes or in flasks, rarely recreates the conditions cells experience in vivo. Over the past 20 years, many researchers have actively sought ways to culture cells in 3D...
At least 80% of cancers are carcinomas, or tumours of the epithelia. Traditionally, cell transformation to a cancerous stage has been evaluated by anchorage dependent growth. More recently, the role of the extracellular matrix, already established in normal epithelial biology, has come to the fore in the study of carcinomas. The extracellular matrix is largely composed of several protein families, notably laminins, collagens and fibronectin. AMSBIO's new white paper focuses on ECM proteins most relevant to cancer research and their use in the oncology field...
Collagen Antibody-Induced Arthritis (CAIA) has been widely used since 1998 when 4-clone cocktail (Arthrogen-CIA® arthritogenic monoclonal antibodies) kits first appeared. In order to induce consistent arthritis more effectively in various mouse strains including CAIA low responder C57BL/6 mice, and a variety of unpredictable knockout and transgenic mice with C57BL/6 (H-2b) or 129/Sv (H-2b) backgrounds, a new 5-clone cocktail kits have been developed by adding a new clone to the 4-clone cocktail...
AMSBIO has added cancer and normal tissue cDNA arrays to its cDNA range which also includes individual PCR-ready first strand samples and panels. The cDNA in each array is synthesized from high quality total RNA from pathologically-verified tissues. Each array is provided with clinical information and QC data that has been both normalized and validated with ß-actin in two sequential qPCR analyses...
Containing nearly 300 biomimetics of Fibronectin, Vitronectin, Laminin and Collagen, for coating plates or creating 3D culture scaffolds, AMSBIO's new ECM combinatorial library provides a powerful tool for identifying the cellular adhesion profile of your cell line or tumour against the widest commercially available collection of cell surface receptor binding peptide motifs...
Gene silencing through the use of RNAi has become a primary tool for characterizing gene involvement in disease states and interactive pathways. Offering genome-wide coverage against human, mouse and rat, the AMSBIO Trilencer-27 siRNA kit takes advantage of the natural processing by Dicer to produce 10-fold higher potency and specificity than shorter 21mer RNAi forms. Beneficially the 27mer dicer-substrate duplexes in the kit also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiate strong and specific gene silencing...
In the article the authors compare cryopreservation of liver hepatocytes using STEM-CELLBANKER with the frequently used DMSO-University of Wisconsin (DMSO-UW) medium protocol. Both protocols yielded hepatocytes with good P450 function, however, the STEM-CELLBANKER protocol gave a higher viability than the DMSO-UW cryoprotectant. The researchers concluded that STEM-CELLBANKER beneficially is also xeno-free and will be applicable to cryopreservation of clinical-grade primary human hepatocytes...
ImmunoPureTM PBMCs are a variety of immune cells derived from the peripheral blood of normal healthy human adult donors collected at IRB-approved blood banks. Seven types are currently available and consist of a variety of immune cells derived from the peripheral blood of normal adults, thereby qualifying them for a diverse number of cell-based experiments...
Driven by the limitations of 2D cell cultures - scientists search for alternative solutions that mirror the environment experienced by normal cells in the body and replicate complex tissue structures and in vivo-like morphology. The '3D Cell Culture in Drug Discovery and Disease Modeling' webinar focuses on discussing the latest advances in 3D technology and its contribution to conducting more realistic research...
AMSBIO's custom generation of stable cell lines includes cloning the gene or shRNA of interest into a safe lentiviral vector, generating the lentivirus and transducing into the cell line of your choice. The service allows you to choose a constitutive or inducible promoter, a tag, an antibiotic selection marker and a fluorescent marker. The ease of providing your target templates or choosing one from AMSBIO's cDNA collection ensures rapid turnaround.
Drawing upon extensive experience of gene silencing techniques the new guide is aimed at assisting research scientists using or planning to use gene knockdown as a method of revealing the function of genes in biological processes. The informative guide provides expert hints and tips on topics including: How to determine the RNAi tools best suited to your application ; The importance of performing appropriate positive and negative controls...
The past few years have seen a boom in the number of papers published covering 3D cell culture, as researchers working in areas from cancer research to stem cells are increasingly seeing the benefits of this technique. AMSBIO supplies the most advanced and extensive range of 3D tools to the life science community...
The AMSBIO Cultrex® 3D Culture Cell Harvesting Kit is based on a non-enzymatic approach that prevents biochemical degradation during processing and overcomes the problems associated with extracting cells from 3D culture in BME or Laminin I. The quality of the harvested cells is ideal for Western blotting and RNA and DNA analysis. In 3D culture, cells are grown in a microenvironment of specialized proteins that mimics in vivo conditions and allows the cells to organise into complex structures rather than uniform monolayers...
AMSBIO provides an extensive portfolio of bromodomains and kits suitable for bromodomain profiling, inhibitor screening assays, and drug discovery. Bromodomains (BRDs) are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine...
AMSBIO has expanded its range of rat specific ELISA kits that enable precise analysis of key neurodegenerative-related biomarkers while minimizing the use of precious samples. Visitors to the recent Neuroscience 2011 meeting in Washington DC responded enthusiastically to AMSBIO's range of over 2300 rat specific ELISA kits tailored for the sensitive and specific quantification of your cytokine, growth factor, or chemokine of interest. Particular interest was shown in new rat specific analyte ELISA kits for various Neurotrophins, TGFb1 and rat leptin as well as a series of ganglioside ELISAs...
AMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...
AMSBIO has added mouse Leukemia Inhibitory Factor (mLIF) to its extensive range of stem cell research products. Functionally tested with mouse ES cells, the affordably-priced AMSBIO recombinant mLIF combines both high quality and high activity. Mouse Leukemia Inhibitory Factor is a lymphoid factor involved in a number of biological processes including neural and hematopoietic cell differentiation, bone and fat metabolism, and mitogenesis of certain factor dependent cell lines...
AMSBIO have added a major new suite of video presentations and a bibliography of downloadable technical papers that demonstrate the utility of alvetex® - a unique synthetic scaffold that enables routine 3D cell culture. alvetex® is a highly porous polystyrene scaffold engineered into a 200µm thick membrane which provides a 3D space into which cells can invade, proliferate and grow. The vertical axis of the third dimension enables additional layers of cells to form complex 3D interactions...
AMSBIO has introduced GeneInTM - a new transfection reagent specifically designed to transfect stem cells and primary cells. Comparative studies against other commercially available reagents show GeneInTM to be superior in transfection efficiency with minimum cytotoxicity...
STEM-CELLBANKER® from AMSBIO is a chemically defined freezing medium with optimized formulation for stem cells and iPS cells storage as well as other valuable cells. Supplied ready-to-use with a simple usage protocol, STEM-CELLBANKER® is completely free of serum and animal derived components, and contains only European or US Pharmacopoeia graded ingredients...
AMSBIO has announced a package of initiatives to support the Glycobiology research community following the recent announcement by Seikagaku Corporation that they plan to discontinue their research reagents and glycobiology biochemicals business as of September 30th 2011...
AMSBIO announces ec23®* - a stable synthetic retinoid that has been proven in independent testing** to potently induce and reliably control stem cell differentiation. Stem cells self renew and have the ability to differentiate into a variety of cell types. They represent a valuable renewable resource from which functional tissues can be derived. Such materials can subsequently be used for research, disease modeling, drug testing and ultimately therapeutic applications...
AMSBIO has announced a new range of Directed in vivo Angiogenesis Assay (DIVAATM) kits that address the short-comings of the traditional plug assay by controlling the site for angiogenesis, increasing reproducibility, conserving test compounds, and supplying more statistical data for quantitative analysis. This range of kits is designed to test for activation, inhibition and tube formation...
AMSBIO has announced the launch of the PluriPCRTM Kit, a new benchmark to revolutionize the definition of stem cell pluripotency. The PluriPCR kit has been designed as a quantitative, easy to use, and reliable assay of five genes strongly specific to pluripotency. These genes: Oct-3/4, Nanog, DNMT3b, Dppa4, and Rex1 are expressed by human embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC); all are sharply down-regulated during differentiation.
AMSBIO is a leading supplier of Mouse Embryonic Fibroblasts (MEFs) and Newborn Human Foreskin Fibroblasts (NuFFs) for mouse and human pluripotent stem cell culture (ES and iPS cells). All AMSBIO feeder cell products are meticulously derived and comprehensively tested on mouse and human ES stem cells to ensure robust and consistent performance with every lot...
AMSBIO has announced the launch of Alvetex® - a unique cell culture scaffold that, for the first time, enables genuine 3D cell culture to be grown routinely and cost-effectively. Already successfully applied to numerous applications including drug toxicity models with liver cells, skin raft assays and bone remodeling studies - Alvetex® provides a stable and inert scaffold for cells to grow, mimicking in vivo growth and formation of tissues in the body...
AMSBIO has announced, as of 31st March 2011, the opening of a new North American subsidiary company - AMSBIO LLC. After successfully selling innovative life science technologies, biotools and services directly to North American researchers, the new office will be a fully integrated entity supporting the AMSBIO product line with a dedicated sales and service facility in Orange County, California...
New independent research demonstrates that the OrisTM Cell Migration Assay presents a superior quantitative, high throughput alternative to the scratch assay. Cell migration is integral to many physiological processes, including embryonic development, tissue regeneration, and wound healing. One assay commonly used to study cell migration is the scratch assay creating a cell-free gap, or "scratch", on a confluent cell monolayer...
AMSBIO has announced a new range of highly efficient knockdown cell lines covering the Base Excision DNA Repair pathway. The new range of 20 DNA Repair Knockdown cell lines was developed to enable scientists to study the molecular etiology of tumour genomic instability and to exploit it in oncology research. The AMSBIO DNA Repair Knockdown cell lines are based upon target-specific LN428 glioblastoma shRNA lentivirus transduced cells that are rigorously qualified and mycoplasma free.
AMSBIO has announced the launch of ecoHSA - an animal-free preparation of the human albumin gene produced in the seeds of Asian Rice (Oryza sativa). Commercial human albumin proteins extracted from plasma have multiple and invaluable uses in cell culture work.
GenePORTER® Gold from AMSBIO is a new highly efficient and reproducible lipid-based reagent for effective transfection of a wide variety of cell lines. Molecular target delivery faces many barriers, from crossing the cell type-specific extracellular membrane, to cytoplasmic degradation and translocation across the nuclear membrane. To be effective, the transfection reagent/DNA complexes must overcome all of these challenges whilst minimizing cytotoxicity
AMSBIO is now able to offer a range of over 4,000 full length affinity purified human proteins expressed in HEK293 cells and derived using an extensive collection of human cDNA clones. The new range is currently the broadest offering of human proteins produced in human cells. It has been prepared to ensure optimal preservation of protein structure, post-translational modifications and functions.
The AMSBIO range of Universal Reference Products (RNA, cDNA and Protein Lysate) has been expanded to include standards for studies involving humans as well as for animal species including Monkey, Dog, Mouse, Rat, and Chicken. These products provide ideal controls for high throughput PCR, RNA microarray and antibody array studies
ExpressArt® mRNA Amplification Kits from AMSBIO offer an elegant technological solution for qRT-PCR and gene expression array studies that overcomes the limitations of sample quality and quantity. ExpressArt® technology allows reproducible and precise analysis of challenging samples including Formalin-Fixed Paraffin-Embedded (FFPE), laser captured micro-dissections, needle biopsies, and circulating tumor cells.
AMSBIO has announced new kits for the isolation of high quality RNA from Formalin-Fixed Paraffin-Embedded (FFPE) tissues and LCM samples that can be applied both to qRT-PCR and a variety of microarray platforms.
AMSBIO has announced an expanded range of assay kits and reagents for the detection and analysis of apoptosis. A new selection guide has been created by AMSBIO to provide researchers with a quick and easy way to identify and select the best tools to measure apoptosis.
AMSBIO has announced the launch of the first of a new generation of cell migration assays designed specifically for fully automated high throughput screening (HTS) utilizing high content screening (HCS) and high content imaging (HCI) systems.
AMSBIO has announced Solu BL21TM Competent E. coli, a significantly improved BL21 host strain for soluble mammalian protein expression. Using a directed evolution approach, a mutant strain of BL21(DE3) E. coli has been developed that can produce soluble protein in the majority of cases where expression in the parent BL21(DE3) yielded no detectable soluble product.