Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Biological Sample Preparation Using a Protein Precipitation Plate

publication date: Nov 21, 2017
 | 
author/source: Porvair Sciences Limited

Porvair Sciences has published an informative video demonstrating how to use a solid-state filter microplate to remove interfering proteins from serum, plasma or even whole blood samples prior to analysis by Liquid Chromatography / Mass Spectrometry (LC/MS).

20171114_2Biological samples commonly contain proteins that interfere with downstream applications. The Porvair Sciences Protein Precipitation Plate (P3) plate uses the CRASH method, in which the protein is denatured with acetronitrile and the flocculant filtered out, allowing 96 samples to be handled at one time. 

Based on the industry standard MicroLute™ format, but without the chromatographic sorbent, protein ‘crashes’ out of solution and precipitates directly in each well when acetonitrile is added, thus solving all common problems associated with the CRASH technique of protein clean-up. The novel dual frit, hydrophobically treated matrix used by the P3 plate means that there is no ‘wetting out’ and leakage of sample before the application of vacuum. Porvair Sciences P3 plate is now commonly used as the protein precipitation plate of choice in many major pharmaceutical companies. 


More about the P3 plate


Established in 1992, Porvair Sciences is one of the largest global manufacturers of ultra-clean microplates for life science, synthetic chemistry and many other applications.  Porvair Sciences Ltd. and JG Finneran are wholly owned subsidiaries of Porvair plc.


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events