Axol Bioscience Launch Human iPSC-Derived Atrial Cardiomyocytes

publication date: Aug 9, 2018
 | 
author/source: Axol Bioscience

Axol-Bioscience-Launch-Human-iPSC-Derived-Atrial-CardiomyocytesA consistent and reproducible model for drug development, toxicity testing and disease modelling applications

Axol Bioscience, the human cell culture specialist, provide highly validated primary cells and iPSC-derived cells together with optimised media and growth supplements, launch their Human iPSC-derived Atrial Cardiomyocytes for the discovery and development of novel treatments and advancing our understanding of cardiovascular disease.

Generated from the same donor as Axol’s highly validated Human iPSC-derived Ventricular Cardiomyocytes, this physiologically relevant human iPSC-derived cell line is quick and easy to use, ready in just 7-days from thaw, for electrophysiology, cardiac contractility study, screening and the investigation of cardiomyopathies.

"We are delighted to announce the launch of Axol's atrial cardiomyocytes. We are proud to say that they are the first and only iPSC-derived atrial cardiomyocyte product currently available to the research market," said Yichen Shi, Chief Executive Officer, Axol Bioscience.

"These cells will provide researchers with a quick and easy to use platform for studying human atrial muscle cells, creating models of atrial-specific diseases, and later developing assays for identifying disease modifying treatments."


"Our staff find iPSC-derived cells much easier to work with, reliably expressing the ion channel biophysics and pharmacology expected of native human atrial cardiomyocytes," said Marc Rogers, PhD, Founding Director and Chief Scientific Officer, Metrion Biosciences.

"We have worked closely with Axol Bioscience during the development and validation of their iPSC-derived atrial cardiomyocytes, confirming them as a robust and reliable stem cell reagent across multiple batches, from pilot to scale-up stage."


Validated through an industry recognised third party and validated against the Comprehensive in vitro Pro-arrhythmia Assay (CiPA) guidelines, Axol’s Human iPSC-derived Atrial Cardiomyocytes express typical targets, ion channels and currents (Kv1.5, Ikir3.x, Ikur, IKACh, MLC2a & ANP) essential for the screening of cross target effects, the development of atrial specific target drugs, and the investigation of atrial fibrillation and inherited cardiac conditions. The overall potential and application of the Human iPSC-derived Atrial Cardiomyocytes can be enriched when cultured with Axol’s serum-free Cardiomyocyte Maintenance Medium, reducing variability and enhancing consistency in their culture.




 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.