Fluidigm Corporation has
announced a collaboration with BD Biosciences, a segment of BD (Becton,
Dickinson and Company), to co-host a public seminar series on the isolation and
analysis of single cells. Entitled 'A Powerful Technique for Single-Cell
Analysis', the public seminar series will showcase cell isolation using the BD
FACSAria
TM III Cell Sorter and analysis using the Fluidigm BioMark
TM HD System.
The combination of the cell surface phenotype obtained from cell sorting and
the gene expression profiles of individual cells isolated from a heterogeneous
population of cells provides a deeper view into cellular systems.
"We believe this emerging field of single-cell genomics research will help
elucidate the underlying biomolecular processes across many diverse biomedical
research areas," said Gajus Worthington, Fluidigm president and chief
executive officer. "Numerous publications in the last two years have shown
that the BioMark System enables important observations of single-cell behavior
in a number of biologically relevant fields, including stem cell research,
cancer research, immunology and developmental biology," Worthington added.
Utilizing cellular and molecular biology to profile single-cell populations
alleviates the complexity caused by cell heterogeneity. BD cell sorting systems
(such as the BD FACSAria III Cell Sorter) provide scientists the flexibility to
isolate single cells of interest from thousands of cells in a population using
up to 18 surface markers. Assessment of cellular heterogeneity and cellular
biomolecular processes is obtained by assaying for differential expression
levels using the BioMark HD System.
"Since the introduction of the powerful BD FACSAria III Cell Sorter, its
immediate improvement on sensitivity and ease-of-use opened the complex world
of cell sorting to a broader audience of researchers, enabling them to perform
a wider range of applications," said James Glasscock, President, BD
Biosciences - Cell Analysis. "We believe that joining our expertise in
cell sorting with Fluidigm's ability to provide real-time polymerase chain
reaction gene expression profiles of hundreds of genes from multiple minute
samples will greatly simplify and advance single-cell research."
The seminar series will discuss the experimental workflows of both companies'
technologies -- BD FACSAria III Cell Sorter and the Fluidigm BioMark HD System
-- that reveal cell population heterogeneity. These public seminars are
currently being held throughout North America.
Fluidigm develops, manufactures and markets microfluidic systems for growth
markets in the life science and agricultural biotechnology, or Ag-Bio,
industries. Fluidigm's proprietary microfluidic systems consist of instruments
and consumables, including integrated fluidic circuits, or chips, and reagents.
These systems are designed to significantly simplify experimental workflow,
increase throughput and reduce costs, while providing the excellent data
quality demanded by customers. Fluidigm actively markets three microfluidic
systems including nine different commercial chips to leading pharmaceutical and
biotechnology companies, academic institutions and Ag-Bio companies. For more
information, please visit
www.fluidigm.com.
* Fluidigm, the Fluidigm logo, BioMark and Dynamic Array NanoFlex are
trademarks or registered trademarks of Fluidigm Corporation.
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