Olympus has introduced the new XLSLPLN25XSVMP SCALEVIEW
25x objective lens with an 8 mm working distance, enabling the deep imaging of
tissues, without the need for potentially damaging micro-dissections. Designed
for use with the SCALEVIEW-A2 clearing reagent, this new objective lens enables
crisp and clear imaging of structures, such as neurons extending 8 mm deep into
tissues, much further than possible before. Optimised for use with the Olympus
FluoView FV1000MPE multiphoton microscope, users can obtain a complete system
which avoids the occurrence of artefacts due to slicing, thus enabling you to
be confident in the biological relevance of your findings.
Following the recent introduction of the SCALEVIEW 4 mm
objective lens, the 8 mm objective, with an NA of 0.9, enables users to look
deep into samples. Both objectives are equipped with a correction collar and
have been optimised for use with the SCALEVIEW-A2 reagent (refractive index
1.38), which essentially clears bodily tissues of their opacity to provide a
clearly defined image. By making the tissue transparent, while simultaneously
minimizing light scattering, images can be obtained from 8 mm below the surface
of the sample. Through the elimination of tissue slicing, it is much easier for
researchers to visualise how neural filaments connect in the brain for example;
a process which is quite difficult when thin sections need to be pieced
together to provide an accurate representation. As such, the SCALEVIEW
objective lenses, in combination with the SCALEVIEW-A2 reagent and FluoView
FV1000MPE microscope, provide a perfect option for developmental biology
studies, as well as imaging and mapping of the brain and other organs.
The revolutionary SCALEVIEW approach was developed in collaboration
with the RIKEN Brain Institute in Japan, where it allowed researchers to create
highly accurate 3D structural representations of brain tissue. As part of a
complete system, the new SCALEVIEW approach integrates seamlessly with
Olympus's FluoView FV1000MPE multiphoton microscopes and the FV10-ASW software
v3.1, providing the power to visualise 3-dimensional structures at
unprecedented depths in morphologically intact tissue
.For further information
click here
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.