Fructosamine is a much earlier indicator of diabetic control compared to
HbA1c providing useful information on an individuals average blood
glucose levels over the preceding 14-21 days. In light of this, the
American Diabetes Association (ADA) recognises fructosamine as a useful
tool in monitoring diabetes control especially in situations where HbA1C
cannot be reliably measured.
Due to its shorter time span,
fructosamine is often measured to evaluate the effectiveness of
medication changes after as little as two weeks. It is also routinely
tested alongside glucose when monitoring insulin requirements during
gestational diabetes. The needs of expectant mothers change frequently
during pregnancy making fructosamine an ideal marker of glycaemic
control.
The more commonly used HbA1c test is based on the
presence of normal haemoglobin making it unsuitable in cases where the
patient has a condition affecting the red blood cells e.g. haemolytic
anaemia, sickle cell anaemia and thalasaemia. In such situations
fructosamine is used as an alternative to tightly monitor glucose
control.
The Randox fructosamine assay is based on an enzymatic
method and therefore doesn't suffer from non-specific interferences like
conventional NBT based methods. All reagents are liquid ready-to-use
for increased efficiency and productivity. Once opened they are stable
onboard the analyser for 28 days at +10oC minimising the possibility of
reagent waste.
The assay is highly precise with CVs less than 3.5% and offers a wide measuring range of 8.12 - 2065 µmol/l.
The
Randox assay is fully automated and suitable for use on a wide range of
clinical chemistry analysers with applications available on request for
the most popular instruments. A dedicated reagent pack is also
available for the Randox RX series of chemistry analysers. Two kit
sizes are available one providing approximately 380 tests per kit and
another providing up to 500 tests per kit. It is important to note that
these numbers will vary according to the instrument used.
Randox
can provide the complete package including calibrators and controls.
Our dedicated fructosamine calibrator and controls are available in 3 x
1ml pack sizes with a working stability of 28 days at 2-8oC.
Fructosamine is also available as a pilot scheme in our RIQAS (Randox
International Quality Assessment Scheme) general chemistry programme.
In
addition to fructosamine we can also provide high quality reagents for
use in the diagnosis of diabetes and the monitoring of complications
associated with diabetes. Available assays include Glucose, HbA1c,
Cystatin C, D-3 Hydroxybutyrate, NEFA, B-2 Microglobulin, Creatinine and
Total Protein.
About Randox Headquartered in the
United Kingdom, Randox Laboratories Ltd. is a market leader within the
in vitro diagnostics industry, manufacturing high quality diagnostic
products for laboratories worldwide. Our extensive product portfolio
offers complete solutions within the fields of clinical chemistry,
cardiology, forensic toxicology, veterinary, drug residues, life
sciences, oncology, molecular diagnostics and internal and external
quality control. Our goal is to ‘revolutionise healthcare through
continuously improving diagnostic solutions.' We continue to achieve
this year after year due to our commitment and significant re-investment
in Research and Development. Our innovative approach to diagnostics
allows us to develop revolutionary products, specifically designed to
provide more efficient, higher quality and reliable results, ensuring
patients receive the right diagnosis at the right time.
For more information contact us at
marketing@randox.com
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