Oxford Gene Technology (OGT), provider of innovative clinical genetics and
diagnostic solutions to advance molecular medicine,
has released a major new update to its
CytoSureTM Interpret Software for array Comparative
Genomic Hybridisation (aCGH) analysis. By utilising an entirely new relational database design, the software now allows sample data to be stored and analysed
in accordance to its relationship with other data. For example, samples can be segregated
into different projects by sample type or by user, thereby simplifying analysis. It can also perform common analysis steps automatically via the "Accelerate
Workflow" mode, which significantly speeds up analysis, especially when working
with a large number of samples. The intuitive graphical interface detects DNA regions exhibiting genomic
variation, with results presented in an easy-to-use
report, annotated with the relevant syndromes, genes, exons, and segmental
duplications. This also includes links to external databases, putting each
variation in context and helping to highlight the biological implications of
the data generated. In addition, this latest software release incorporates a
number of cancer annotation tracks, enabling meaningful interpretation of
results obtained using OGT's growing portfolio of
CytoSure Cancer arrays.
Dr. Agne Liedén from the Department of Molecular Medicine and
Surgery at the Karolinska Institutet, who has recently integrated the new
CytoSure Interpret Software into his laboratory's workflow, commented: "I have
been extremely impressed with the ease-of-use and flexibility of the software.
In our experience, OGT is very responsive to customer feedback and has produced
an excellent software package." OGT's
CEO, Dr Mike Evans, said: "The new update is part of OGT's overall strategy,
which is dedicated to providing products and services that convert complex
datasets into easily interpretable, meaningful results. Our aim is to allow
researchers to focus all of their time and energy on investigating the biology,
rather than sifting through their data. In this case, constant innovation
ensures that our CytoSure Interpret Software remains the industry-leading aCGH
analysis software, and our dedicated software development team are continually
implementing enhanced features and capabilities in response to customer
feedback and new developments in the field."
To complement OGT's growing range of proprietary arrays
containing both
CNV and SNP probes, CytoSure Interpret
Software can identify DNA regions exhibiting copy number variation, loss of heterozygosity and
mosaicism. The latest update also provides a unique ‘Family Tree' view, which
makes it easy to examine inheritance patterns in up to three generations of the
same family. In addition, to further ensure reliable, consistent results, the
latest version of CytoSure Interpret Software incorporates permission-based account management. This allows
individual users to be assigned specific, customisable access to system
functionality and delivers a comprehensive audit trail of any workflow changes,
thereby providing consistency of analysis and reporting.
For more information about
OGT's CytoSure Interpret Software, or the company's other genomic and biomarker
services and products, visit the new OGT website at
www.ogt.co.uk.
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