SAW Instruments GmbH, developer of
innovative biosensor technology for life sciences research in biotech and
academia, will present a poster at this year's
MipTec meeting,
Basel, Switzerland (20-22
nd September). Entitled
"Binding
Kinetics of Therapeutic Antibodies to Native Proteins on Living Cells", the
new poster discusses recent work carried out in collaboration with Affimed
Therapeutics AG
(full abstract on SAW website). The poster
provides kinetics data illustrating the interaction of one of Affimed's
therapeutic antibodies with living tumour cells, including a comparison of K
D
values obtained using SAW instrumentation, with values previously
calculated by FACS and ELISA. The poster will be available for viewing on
Thursday 22
nd September, 1pm-2.30pm (Poster Number 207), with SAW
personnel on hand to provide more information and further discussion.
As well as the
poster, SAW will release and demonstrate the new sam®X at MipTec 2011, the
latest member of the
SAW biosensor product family. sam®X expands the power and flexibility of the
portfolio by empowering users through workflow-driven features, including an
increase in the number of sensor chips to two, providing a total of 8 channels,
each of which can be addressed individually or in user-specified combinations.
The sam®X will be demonstrated at booth A49, where dedicated application
specialists will be providing answers to any questions and showing the system
in action. Personal demonstration slots will also be available, which can be
reserved before the event via
the SAW website.
For more
information on the innovative sam® biosensor range, visit MipTec booth A49 or
see
www.saw-instruments.de.
Notes on the technology
Surface Acoustic Wave technology is based
on the ability of a wave of energy to travel across the surface of a material.
Each surface has a typical inherent elasticity affecting the way the energy of
the wave dissipates as it travels across the surface of the material being
analysed. Thus, the nature of the surface in question, and therefore any
changes to it, can be assessed by sensors monitoring the behaviour of the wave
as it propagates across the surface. In particular, changes in mass result in
alterations to the phase of the wave, whilst viscoelastic and conformational characteristics
influence wave amplitude. The technology developed and employed by SAW
instruments is capable of accurately interpreting this information in order to
provide real time readouts measuring binding and conformational changes in the
samples through which the wave passes.
About SAW Instruments GmbH
SAW Instruments GmbH designs, develops and sells
biosensor-based laboratory instruments for life sciences research. The
proprietary technology of SAW Instruments employs a Surface Acoustic Waves
approach to biological measurement, rather than using traditional optical
methods such as SPR. The technology is uniquely positioned compared to other
biosensor technologies based on its ability to measure conformational changes
in cells, membranes and vesicles. In addition, the system is also capable of
providing other industry standard measurements including those involving
kinetics, quantitation and affinity.
SAW instruments has more than ten years experience in
the field of label-free biosensor technology and a number of our customers have
successfully published work employing the platform. It is our goal is to
continue to build on this experience, as well as to develop a family of
workflow-driven products to further meet our customers' needs.
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