Syngene, a world-leading manufacturer of image analysis
solutions today introduced its new generation UltraSafe Blue
TM a non-toxic,
non-carcinogenic fluorescent dye specifically developed as a safer and
more sensitive alternative to Ethidium
bromide for staining agarose and acrylamide gels.
UltraSafe Blue from Syngene is a new generation of safe fluorescent
nucleic acid stain which allows detection of 0.5pg of dsDNA using Syngene's
new UltraSlim-LED blue-light transilluminator.
Additionally, because UltraSafe Blue is a non-intercalating
stain there is less effect
on the quality of the DNA or RNA. Nucleic acids stained with UltraSafe Blue can
be more easily used in downstream experiments such
as RT-PCR, enzyme digestion and
ligation, thus saving time and effort with multiple purification steps.
UltraSafe Blue is very cost effective, with 1ml of stain being sufficient for
up to 10,000 samples and using this dye also means making
cost savings for many institutions, as
gels do not have to be disposed of as hazardous waste.
Laura Sullivan, Syngene's
Divisional Manager explained: "Ethidium bromide is probably the most
well-known dye used for visualising DNA
but because it intercalates into the DNA
strands it is a potential carcinogen and mutagenic agent, so must be handled
with care and usually requires exclusive bench space in order not to
contaminate the entire laboratory."
Laura continued: "We're very excited to offer
scientists our own safe alternative to Ethidium bromide. This new generation dye
is less dangerous to work with, doesn't compromise nucleic acid quality and
shows a very good staining performance, making UltraSafe Blue the ideal choice
for safety-conscious researchers."
For more information visit
www.syngene.com/reagents-and-dyes/
