publication date: Dec 13, 2018
|
author/source: Metrohm AG
One of the main goals of the USP monograph modernization initiative is to replace non-specific methods with highly selective and sensitive instrumental analysis methods.
Based on a joint project with Metrohm, the USP proposes a new ion chromatography method for chloride and sulfate detection in drug substances, potassium carbonate, and potassium bicarbonate.
Chloride and sulfate are common impurities present in drug substances and drug products. Current limit tests as per USP general chapter are based on turbidity and/or visual comparison methods. Both methods lack specificity and fail the requirements of data integrity.
Addressing these shortcomings, the USP proposes a selective and sensitive ion chromatography method for chloride and sulfate detection in drug substances, potassium carbonate, and potassium bicarbonate. The method is described in a free technical poster.
View | Download Poster
more from Metrohm
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.