Olympus has released the new FV10MP-BXD-GAP photodetector
for enhanced sensitivity when performing multi-photon fluorescence imaging. The
new non-descanned detector unit is ideal for capturing very faint fluorescence
signals and for minimising the laser power required to generate a detectable
signal, making it the best choice for advanced life science research.
Exceptional sensitivity is achieved by coating the photoelectric surface of the
detector with Gallium Arsenide Phosphide (GaAsP), which offers superior quantum
efficiency compared to conventional PMTs. In addition, noise is kept to an
absolute minimum via the use of Peltier cooling, boosting signal-to-noise
ratio. The detector unit also includes standard PMTs, allowing these to be used
for identifying regions of interest (ROI) which can then be scanned using the
GaAsP PMTs, maximising their lifetime. When used in combination with a member
of the Olympus range of FluoView FV1000MPE multiphoton microscope systems, researchers
can produce insightful images, even when using advanced irradiation techniques,
low laser power or very faint fluorophores.
The new FV10MP-BXD-GAP non-descanned photodetector from
Olympus has been designed to make the best use of every photon emitted by a
sample. Efficient photon detection means that a wide range of biological
processes can be investigated using fluorescently-tagged molecules expressed at
physiologically relevant concentrations, even at levels that were previously
too low to be detected using traditional multi-alkali PMTs. In addition, as a
lower intensity of laser light is required to accurately detect each
fluorophore, the power of the laser can be reduced. This minimises the effects
of photobleaching and phototoxicity, thereby increasing the accuracy and
biological relevance of results, especially for experiments performed over long
time periods or requiring frequent laser light exposure.
The FV10MP-BXD-GAP is equipped with 2 conventional
multi-alkali PMTs for the routine browsing of samples, and 2 GaAsP PMTs for the
highly sensitive analysis of a specific ROI. Switching between the two types of
detector is easy and fast, providing a hassle-free workflow. To further
lengthen the lifetime of the GaAsP PMT, the system prevents any unnecessary
exposure to ambient light such as room lighting or excessive fluorescence. The
FV10MP-BXD-GAP can be purchased as part of a new FluoView system, or can be
used to upgrade an existing setup, where it will provide the sensitivity
required to produce high quality images, facilitate accurate photon detection
and allow even deeper imaging via multiphoton microscopy.
For further information visit
www.microscopy.olympus.eu
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.