A
next generation of glass reduces the interaction of analytes and the glass
- Detect Low Abundance Analytes
Normally Adsorbed by Glass
- Prevent pH changes in vials
before injection
- Prevent hydrolysis that can
occur in your vials
Made with a new patent
pending, glass manufacturing process, RSA GlassTM vials and inserts have reduced surface
activity for basic compounds. This is due to the elimination of virtually all
silanols (hydroxyl groups) that can have deleterious effects on your analytes
and sample solutions.
RSA
TM autosampler vials and glass inserts are
not manufactured with coatings;
but have significantly reduced silanols on the glass surface normally produced
during the manufacturing process. This lack of surface silanols makes them an
excellent choice for GC and GCMS applications.
With standard borosilicate glass vials and inserts sample diluents (such as
water) can de-protonate the many surface hydroxyl groups; producing a negative
charge on the glass wall. The "acidic" functionality of silanols has been known
to cause adsorption of basic compounds, change the sample solution pH and/or
hydrolyze susceptible compounds rendering them undetectable. With RSA Glass
TM
vials and inserts there is virtually no sample "loss to the vial" and no "pH
shifting" making your analysis more reliable.
If you are working with low abundance basic samples with regular glass
vials, it is very possible that your compounds could easily be adsorbed to the
glass wall. This can change your quantitation or completely remove the compound
from solution preventing injection and ultimately masking its detection and
identification. With RSA Glass
TM vials and inserts this will not occur if the
adsorption is due to silanol interaction.
If you are working with sensitive compounds commonly found in natural
products, biological samples or chemical synthesis, the glass wall could be
a problem for basic compounds. With RSA Glass
TM vials this problem is
eliminated.
If you are working with basic proteins that adsorb or are affected by silanols;
RSA Glass
TM vials and inserts will be a good solution for you. If your proteins
are sticking to the glass due to adsorption to the siloxane surface, RSA Glass
TM
provides an almost completely silanized surface. The results of silanizing RSA
Glass
TM over standard borosilicate glass is far superior for proteins and
peptides if this option is desired.
RSA Glass
TM has been tested for
metals that may cause sample or diluent
contamination. It has
ULTRA low levels of Sodium, Calcium, Aluminum and
Boron. Sodium and Boron levels are 200 to 300 times less concentrated compared
to leading manufacturers with Calcium and Aluminum almost non-detectable.
Testing was done using ICP with water from the vials and a 4 hour
"soak" time.
There is
no significant cost increase for RSA Glass
TM vials and inserts.
They are QC tested to meet or exceed any commercially "certified" vial or
insert. That is our promise. Manufacturer MicroSolv. Patent Pending.
For
further information on RSA vials contact Hichrom Limited, UK, Tel: +44 (0) 118
930 3660
technical@hichrom.co.uk
or
click here
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