publication date: Jan 6, 2021
|
author/source: YMC Europe GmbH
Are you characterising ADCs via HIC? Do you want to determine the DAR using MS without the need for peak isolation?
In this application note the drug-to-antibody ratio (DAR) of a cys-linked ADC-mimic is determined using online native HIC-MS. Using the innovative BioPro HIC BF column and a direct coupling to the mass spectrometer even degraded payloads can be detected. The application also demonstrates how to overcome the high salt concentrations which are necessary for HIC methods.
To get more details download the application note or visit our homepage to receive more information on YMC’s HIC columns for BioLC.
download application note
YMC’s HIC columns for BioLC
more news from YMC
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.