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Explaining molecular sizing using GPC/SEC
For many applications that include the use of biologically important molecules, such as proteins or polysaccharides, molecular size is an important parameter but its accurate measurement can be challenging. A new application note from Malvern Instruments describes the use of triple detection gel permeation/ size exclusion chromatography (GPC/SEC) using the VIscotek TDAmax system for this purpose. It examines the rationale for triple detection GPC/SEC and looks at the benefits when making key measurements that include radius of gyration (Rg) and hydrodynamic radius (RH).
To download the application note please click here
For more information about the Viscotek TDAmax please click here