In this article, the characterization of lactose powders for use in DPI applications is discussed. We present new results obtained from state-of-the-art characterization methods allowing us to gather insightful information on the powder behavior. Moreover, electrostatic properties which are of great interest for DPI applications in particular with respect to drug release from the lactose carrier are investigated....

INTEGRA Biosciences has made significant progress towards its goal of minimizing its ecological footprint with the installation of new photovoltaic systems at the company’s US facilities in Hudson, NH. These systems will provide 77 percent of the total energy requirement for both the company’s US headquarters and production center, saving as much CO2 as 2900 cars or 2300 single-family homes produce in the USA each year....

As a project company of Xlife Sciences AG (XLS DE), inflamed pharma GmbH has developed a revolutionary and holistic therapeutic approach to treat both SARS-CoV-2 and flu viruses. The patented active substance ProcCluster(R) reduces the viral load by 90% and acts against infection-related inflammatory processes without developing a resistance. It is already used on humans...

Thermo Fisher Scientific, the world leader in serving science, and Newomics, a commercial-stage biotechnology company, are collaborating to develop a novel native liquid chromatography-mass spectrometry (LC−MS) platform to support various LC−MS applications. This agreement utilizes Newomics’ experience in creating innovative and integrative platforms and solutions for precision medicine and Thermo Fisher’s cutting-edge LC-MS systems...

Largest reported organ-on-a-chip screen ever performed on a 3D angiogenesis assay. MIMETAS, the global leader in human-relevant organ-on-a-chip models, has just opened their Phenotypic Screening Center. The center facilitates large-scale screening campaigns on Organ-on-a-Chip models, a powerful technology that improves the human physiological relevance of cultured tissues by utilizing microfluidic techniques....

Aptamer Group Limited, the developer of Optimer™ Therapeutics, and PinotBio (Gyeonggi-do, Korea), a clinical-stage oncology-focused biotechnology company, have entered into a strategic collaboration agreement. The agreement is to develop Optimer-drug conjugates for targeted drug delivery combining Aptamer Group’s Optimer technology with PinotBio’s technology using the chemotherapeutic FL-118 compound with specific linker....

Avacta Group plc the developer of diagnostics and innovative cancer therapies based on its proprietary Affimer^® and pre|CISION™ platforms, is pleased to announce that the MHRA has confirmed registration of Avacta’s AffiDX^® SARS-CoV-2 antigen lateral flow test allowing the Company to place the product on the market in the UK for professional use...

AMSBIO reports upon a publication that cites how its STEM-CELLBANKER® animal-free cryopreservation media has played a role in the development of a cell therapy for Parkinson’s Disease that will soon be going into clinical trials. Parkinson’s disease is one of the most common neurodegenerative diseases worldwide. Its main features include motor symptoms such as bradykinesia, rigidity, resting tremor, and postural instability, though non-motor symptoms are often also present....

Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced that it has entered into an agreement with Thermo Fisher Scientific for fill/finish sterile manufacturing services and supply packaging for Moderna’s COVID-19 vaccine. Under the terms of the agreement, Thermo Fisher’s commercial manufacturing site in Greenville, North Carolina will be used for aseptic fill/finish, labeling and packaging...

e-MSB 2021 has partnered with Virtual Creative Studios to provide an immersive conference experience that mimics the collegial atmosphere of in-person MSB meetings. The program will deliver strong scientific content with opportunities for engagement and building connections. The program will be packed with four full days of invited and contributed talks, general and parallel sessions with heavy focus on live Q&A by world renowned experts...

The very high use of antibiotics in patients hospitalised with COVID-19 is often not necessary, and risks worsening global antimicrobial resistance. New research led by the University of Glasgow as part of the ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) WHO Clinical Characterisation Protocol UK (CCP-UK), found that antibiotic use was very high in hospitalised COVID-19 patients in the UK during the first wave despite confirmed bacterial infection being uncommon....

A unique electron microscope, set to break new ground in biological imaging, is being installed at the Franklin’s new building on the Harwell campus. The machine is able to image biological samples at up to a million frames a second, a thousand times faster than the current standard. It is the first of three instruments being developed jointly with electron microscope manufacturer, JEOL Ltd, and has been shipped to the UK from the company’s headquarters in Japan....

While the cultured meat industry is gaining momentum, scaling up the production process and reducing the cost remain key challenges. The primary focus of the collaboration between Merck and the two universities will be the development of next generation, scalable bioreactor designs that can support meat and seafood manufacture on a commercial scale....

The first study of its kind reports on the enhancement of skin permeability of risperidone (RIS) using eutectic systems. A recent study undertaken at the University of Petra in Jordan describes for the first time the formation of room temperature therapeutic deep eutectic solvent (THEDES) of RIS, an antipsychotic drug that is used in the treatment of schizophrenia, mixed and manic states associated with bipolar disorder and irritability in children and adolescents with autism....

Malvern Panalytical was delighted to welcome His Royal Highness The Earl of Wessex to its Malvern, Worcestershire, headquarters. Malvern Panalytical was selected for the Royal visit, amongst a small number of other Worcestershire businesses, primarily because of its scientific and technical contribution to the development of medicines and vaccines to treat and prevent COVID-19...

SP Scientific Products (SP) has announced one of the world’s largest simultaneous installations of commercial lyophilizers for use in the production of diagnostic tests. The order, for SP lyophilizers, was made last year by a leading global healthcare company in response to the need for an increase in SARS-CoV-2 testing. With the urgency of the pandemic and requirement for speed, SP was able to complete the delivery of 16 freeze dryers – including manufacturing, testing, and installation - in just four months...

To meet the high demand for lipids, a key component of mRNA-based vaccines and therapeutics, Merck, a leading science and technology company, has launched a new, high-purity synthetic cholesterol product, nine months ahead of schedule. “Tapping into two decades’ experience of developing and manufacturing high-quality lipids, we designed a proprietary process to bring our new SAFC® synthetic cholesterol product to market nearly a year early,” said Andrew Bulpin...

Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, and Samsung Biologics, a leading global CDMO providing a fully integrated end-to-end contract development and manufacturing service, today announced a Manufacturing Services and Supply Agreement in which Samsung Biologics will provide large scale, commercial fill-finish manufacturing for mRNA-1273, Moderna’s COVID-19 vaccine....

A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the pharmaceutical sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation...