Refeyn, the company behind pioneering mass photometry technology, announces that mass photometry has been recognized by the U.S. Pharmacopeia (USP)—and referenced in the new draft USP general chapter <1067>—as a key orthogonal method for characterizing USP’s new adeno-associated virus (AAV) reference standards. As a major advancement in gene therapy quality, USP has recently released new standards for measuring empty and full AAV capsids using five different methods from a comprehensive multi-laboratory study...

Data stands at the centre of transformation in today’s digital labs — both as a major obstacle and a driving force for innovation, according to a survey of more than 150 scientists from Titian Software and Labguru. Data overload and management were identified as the most significant challenges impacting lab operations. This same data deluge offers a powerful opportunity: respondents cited AI’s potential to manage and extract insights from the vast volumes of data generated by experiments...

INTEGRA Biosciences’ liquid handling solutions and pipette automation software are helping 3T Biosciences – a biotech company based in South San Francisco, California – to enhance the reproducibility and productivity of its pipetting workflows, accelerating the discovery of novel cancer targets and therapeutics. Patients diagnosed with solid cancers or autoimmune diseases often have limited and ineffective treatment options...

Low-pressure GC-MS (LPGC-MS) is a chromatography technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, thereby significantly speeding up analysis. In addition to the speed benefit, LPGC-MS can also provide a cost savings by dramatically reducing helium consumption...

Thermo Fisher Scientific, the world leader in serving science, has announced that the Regeneron Genetics Center® (RGC™) has selected the Olink Explore HT proteomics platform for a large-scale proteomics investigation involving nearly 200,000 patient samples from the Geisinger Health Study that aims to unlock new insights into the dynamic biology and mechanisms of human disease...

In case you missed it, Prior Scientific's Product Manager, Simon Bush, recently delivered an informative online presentation titled “Modular Microscopy for Prototyping and Discovery” at the BioPhotonics Microscopy Summit. This session showcased how Prior's innovative OpenStand microscopy platform and our adaptable automation components can play a vital role in today's microscopy landscape...

In a new independent research report by SuperMicrobiologistes, technicians and lab managers share their work experiences using the Inlabtec Serial Diluter. To help microbiology labs solve long-standing problems with repetitive manual serial dilution techniques that strain technicians and limit efficiency, Inlabtec developed their automated Serial Diluter UC system. To secure feedback that truly represents why microbiology labs are adopting automated serial dilution – SuperMicrobiologistes interviewed users...

Analysis of PFAS in human serum using a YMC-Triart C18 column in combination with an online SPE column-switching method. A highly sensitive LC-MS/MS method for the analysis of 28 PFAS in human serum is demonstrated in this Application Note. By combining online SPE and the robust YMC-Triart C18 column, this setup ensures excellent separation, high throughput and reliable quantification...

PacBio a leading provider of high-quality, highly accurate sequencing platforms, and Chulalongkorn University, a national leader in genomic and translational research, today announced a strategic collaboration to implement PacBio HiFi whole genome sequencing (WGS) as part of a newborn screening research program...

IBMS, BD and PLMR Healthcomms have released a new paper, Lost in the Bloodstream – A Holistic Approach to Blood Culture Improvement, which brings together the experiences and insights of NHS professionals across the blood culture pathway. Based on national FOI data and in-depth interviews, the report highlights the need for more consistent and collaborative approaches to reduce contamination...

New AI-powered, robotic labs that will accelerate development of new treatments for deadly diseases are to be built in Liverpool after £10m Innovation Zone funding was agreed. The High Containment Level 3 labs, located at the Liverpool School of Tropical Medicine (LSTM) and supported by the Infection Innovation Consortium (iiCON), will be capable of handling a range of pathogens during development and validation of new treatments that could save lives worldwide...

Onboard the International Space Station (ISS), the Extant Life Volumetric Imaging System, dubbed ELVIS, is not about resurrecting rock-n-roll legends but pioneering scientific discovery. Using innovative holographic technology to deliver detailed 3D views of cells and microbes, the system allows scientists to study the adaptability and resilience of life under extreme conditions. Knowledge gained could reveal how life might persist on distant moons and planets, significantly enhancing our search for life outside Earth...

This Application Note presents an optimised SEC-MS method for the high-performance separation and characterisation of a single-chain variable fragment (scFv) and its drug conjugates (FDC). Using a bioinert PEEK-lined YMC-Pack Diol-120 metal-free column combined with MS compatible conditions delivers sharp peaks & precise resolution, enhanced signal response and reliable results. Boost your analytical expertise – download the Application Note now!...

TESTA Analytical reports a major polymer manufacturer is using their COMBO-ONE detector, as part of a GPC/SEC system, to characterize the structure of macromolecules that offer desirable performance properties. The client is a leading European manufacturer of high-performance water-soluble polymers for industrial applications. These polymers, although presenting a similar molecular weight and molecular weight distribution, have different physical structures which influence their performance in the target application...

Illumina Inc. and Nashville Biosciences, LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), have announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative. Insights from the AGD database are being leveraged to accelerate drug target discovery, therapeutic research and clinical development...

New alliance for advanced biological imaging aimed at enhancing some of the world's most innovative structural cell biology capabilities to help scientists answer pressing research questions. Thermo Fisher Scientific Inc., the world leader in serving science, has announced a Technology Alliance Agreement with the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute). This agreement aims to develop new technologies to enable researchers to better visualize human cells, significantly advancing scientific research and discovery...

Scientists at the Technical University of Munich (TUM) have developed a method that relies on physics rather than conventional chemistry to obtain the proteins that are needed for this purpose. Using short-wave, UV light invisible to humans, they have succeeded in purifying proteins from cell extracts or cultures. This technique is more efficient and gentler than previous methods...

Scientists at Novo Nordisk in Denmark have applied flow chemistry to enhance the cleavage of oligonucleotides. Utilising Vapourtec’s R-Series flow chemistry system to undertake their research, the Novo Nordisk team have made the data available in an application note that will be of interest to all chemists exploring oligonucleotides. The improvements reported include a reduction in the time for cleavage and complete deprotection to less than 3 minutes...

Scientific Laboratory Supplies (SLS) and Grant Instruments have produced a case study aiming to bring greater transparency to product sustainability. Whilst qualitative insights provide a strong foundation, data-driven sustainability requires measurable carbon data. This case study explores how collaboration can help laboratories make informed purchasing choices by assessing the full environmental impact of a product’s lifecycle...