Follow us...

 

Search News Archives

Channels

News

 

 

View Channel

Laboratory Products

 

 

View Channel

Special Offers and Promotions

 

Microscopy | Image Analysis

 

 

View Channel

Separation Science

 

 

View Channel

Coronavirus (COVID-19)

 

 

View Channel

Research & Case Studies

 

 

View Channel

Brochures & Literature

 

 

View Channel

 

Conferences | Events

Lhasa and Optibrium Enter Research and Product Development Collaboration

publication date: May 16, 2017
 | 
author/source: Optibrium

Drug discovery software specialists combine expertise to extend studies into drug metabolism modelling

OptibriumOptibrium™ and Lhasa Limited (Lhasa), developers of software for small molecule property prediction, design and optimisation, announced today they have formed a collaborative partnership to research next generation drug metabolism modelling. Results from the work will be used by both organisations in the development of future products with improved and extended metabolism prediction capabilities.

The development of methods to predict metabolism is an important avenue of research and finds application in the development of drugs, cosmetics, nutritional supplements and agrochemicals. It is necessary to understand a compound’s pharmacokinetics and ensure that it has sufficient exposure at a target to exert its therapeutic effect. In addition to this, it is important to predict the formation of toxic metabolites, which contributes to the high attrition rates experienced in the development of new chemical entities, the imposition of black-box warnings or even the withdrawal of approved pharmaceuticals. Therefore, the ability to identify potential metabolite issues early is of crucial importance to improving the efficiency and safety of the drug discovery process.

The research project has appointed Dr Mario Öeren as Senior Scientist to lead the study and work with a team of scientists from both Lhasa and Optibrium. As a theoretical chemist who has specialised into computational chemistry, Mario has a PhD in Natural Sciences from Tallinn University of Technology, Estonia where he has since worked as a researcher and lecturer. Mario will be based at Optibrium’s headquarters in Cambridge, UK.

Dr. Matt Segall, CEO at Optibrium said: “This R&D collaboration with Lhasa builds on a long-standing relationship and is part of our continued investment in the development of novel technologies to improve efficiency in drug discovery. We welcome Mario to the team and look forward to extending the metabolism modelling capabilities within our combined product portfolio for the mutual benefit of Lhasa members and StarDrop users.”

Dr. Chris Barber, Director of Science at Lhasa added: “We are excited by the complementary approaches that Lhasa and Optibrium have applied in the past with Lhasa capitalising on data donated by its member organisations and Optibrium applying theoretical approaches.  Both approaches have their advantages but combining and applying them across all stages of development should allow us to provide real benefit to the end user.”

In StarDrop, Optibrium has developed a comprehensive suite of integrated software with a highly visual and user-friendly interface. It enables a seamless flow from the latest data through to predictive modelling and decision making regarding the next round of synthesis and research, improving the speed, efficiency and productivity of the drug discovery process. Seamlessly connecting with other models, informatics methods and databases, StarDrop provides user-friendly access to resources making project management quicker and simpler.

Lhasa specialises in the development of transparent in silico models together with supporting databases in the fields of toxicology, metabolism, degradation and organic synthesis. The company is considered a pioneer in the production of knowledge-based systems and Meteor Nexus, the expert knowledge-based system for the prediction of metabolism, is used extensively within the pharmaceutical and related industries.


more about optibrium


more news from optibrium


 

 

 


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month...

Our Top 10 most popular articles this month

 

Today's Picks...

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners