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Postnova FFF/SEC Platform Advances Protein Separation And Characterisation

publication date: Jul 11, 2017
 | 
author/source: Postnova Analytics GmbH

Postnova Analytics reports on the extended data available through integrating its AF2000 MultiFlow Flow Field-Flow Fractionation (FFF) platform with its SC2000 modular multi-detector Size Exclusion chromatography (SEC) system.

AF2000Drawing on over three decades of cutting-edge separations leadership, Postnova has designed an advanced orthogonal system that allows both SEC and FFF separations to be carried out on the same sample within one instrument platform. The result is enabling labs around the world to generate more useful information from even complex proteins, antibodies, polypeptides and polysaccharides.

As both separation techniques in the Postnova 2000 Series FFF/SEC system can use the same optimised detector set - UV, RI and MALS (Multi Angle Light Scattering) realising the enhanced applications potential of the integrated system is achieved with minimal redundancy using an automatic switching value and software upgrade kit. 

Offering orthogonally operating separation techniques in same platform, the Postnova 2000 Series FFF/SEC system delivers unmatched diagnostic flexibility across an increased application range.  The system can be run with different eluents, pH and wide-ranging temperature conditions making it an ideal platform for the characterization of natural or synthetic macromolecules.

Postnova FFF technology employs a unique crossflow field in which samples are separated by their dynamic diffusion based on molar mass or particle size. Because of this design and the absence of any stationary phase, separations are performed without exerting shear forces and stress on the molecules.

Founded in 1997, Postnova Analytics is the inventor and leading international supplier of Field-Flow Fractionation (FFF) systems for markets including biopharmaceuticals, polymers, materials, nanotechnology and environmental sciences. Leveraging its unique and patented modular FFF - Light Scattering Platform, Postnova has been able to provide high performance solutions to a wide range of applications. Today the company's growing product portfolio includes Flow FFF, Centrifugal FFF, Thermal FFF, Size Exclusion Chromatography (SEC), MALS and DLS Light Scattering.  Postnova is located and headquartered in Landsberg am Lech (Germany) and has subsidiaries in the USA, UK and Finland. These offices in conjunction with a highly qualified and trained distribution network provides informed local support to customers worldwide.


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