Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Agilent Announces Cell Analysis Workflow Automation for Immuno-Oncology, Virology, and Vaccine Development Markets

publication date: Mar 24, 2023
 | 
author/source: Agilent Technologies

agilent-announces-cell-analysis-workflow-automation

New workflow integrates the xCELLigence RTCA HT with the BioTek BioSpa 8 Automated Incubator

Agilent Technologies Inc. has announced their xCELLigence RTCA HT (real-time cell analysis high-throughput) platform now integrates with the BioTek BioSpa 8 Automated Incubator. Developed in response to market needs, this combination enables a higher level of workflow automation that provides novel functionality for the development of label-free high-throughput potency assays for the immuno-oncology space and high-throughput viral cytopathic effects (CPE) assays for the vaccine market. 

Faced with fierce competition to fulfill the promise of immuno-oncology therapeutics, pharma researchers are rapidly evolving the approaches used to accelerate clinical success. Similarly, vaccine developers are under unprecedented pressure in light of constantly shifting public health threats. Automated workflows offer the promise of increasing drug candidate screening as a means to more quickly and efficiently translate research into discovery. However, many existing automated workflow solutions still rely on substantial manual intervention steps that hinder throughput and limit the scope of assay development.

The xCELLigence RTCA HT - BioSpa 8 integration offers a label-free, non-invasive, kinetic readout of cell proliferation and cytotoxicity that allows researchers to analyze up to eight 384-well E-Plates, increasing throughput and decreasing sample sizes. The BioSpa 8 incubator provides real-time temperature and CO2/O2 control with humidity monitoring. The xCELLigence instrument is equipped with a heated cradle, so cells are protected against unnecessary perturbances and fluctuation of culture conditions during the automated transfer from the incubator. User-friendly software facilitates automated assays and data analysis, making this a true walk-away system for identifying therapeutics to fight disease and providing a degree of automation that is unique to this combination of technologies.

“This is an innovative solution for immuno-oncology therapeutic and vaccine development, demonstrating Agilent’s ongoing commitment to fighting cancer and infectious diseases,” said Todd Christian, vice president and general manager of Agilent’s Cell Analysis Division. “Integrating our non-invasive, and real-time cell analysis measurement capabilities and physiological incubation provides a simple, automated workflow for increased throughput and screening flexibility under physiological conditions.”

“The xCELLigence RTCA HT technology has been key to facilitating high-throughput, rapid, and quantitative cytopathic effect (CPE) monitoring as a tool to assess neutralizing activity and potency,” said Dr. Robert Carnahan, associate director of the Vanderbilt Vaccine Center at the Vanderbilt University Medical Center. “We were able to bypass a multitude of hands-on, multistep processes required by plaque or focus-forming assays to measure viral activity.”

Agilent provides products and services that facilitate drug discovery across a broad range of disciplines and approaches, including tools for real-time cell and metabolic analysis, as well as flow cytometric, plate-based, and imaging/microscopy platforms. The announcement of this new integrated solution reinforces our commitment as a partner for solving real-world challenges in the drug development space.

 

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in the life sciences, diagnostics, and applied chemical markets, delivering insight and innovation that advance the quality of life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.85 billion in fiscal 2022 and employs 18,000 people worldwide.

 

Recent news from Agilent Technologies

 


If you have not logged into the website then please enter your details below.



 

News Channels

 

 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 

 

 

 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events