Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published an update to its guide on “Environmental Monitoring Processes and Validation”, incorporating specific detail on the new version of EU GMP Annex 1. This aims to help sterile medicinal product manufacturers with reviewing and improving their Environmental Monitoring (EM) programs in preparation for compliance with the revised guidelines by August 2023...

The UK’s largest distributor of scientific instrumentation, SciMed, has released a new whitepaper that shares advice with the laboratory industry on ways it can become more sustainable without increasing costs or harming experimental efficiency. These include reducing the use of harmful solvents in procedures such as separations and extractions and using new technology that reduces utilities consumption in lab environments...

ViroStat has just released its new catalogue of infectious disease antibodies and antigens. This newest release includes 790 antibodies for use in antigen detection assays such as lateral flow rapid tests, ELISA, IFA and CLIA. Many recommended pairs are available. Infectious targets include viruses, bacteria, toxins, parasites and fungi. Download your digital copy or request a hard copy of this new catalogue...

Engineering Experience and Expertise to Help You Protect Investments and Maximize Equipment Productivity. SP Service offers an exceptional depth of expertise to help keep equipment performing at its very best. We are recognized experts in applications, methodologies, laboratory and manufacturing processes, and many other areas that directly impact your facility's day-to-day operation...

AMSBIO has published an informative handbook for scientists who need to preserve or archive organoids in a research lab. The handbook brings together published paper citations, quotes and data from leading international research groups who are using the CELLBANKER® range of products to cryopreserve their organoids simply and safely. In addition, the handbook includes best practice protocols plus information making it easier to understand the process of freezing organoids...

INTEGRA Biosciences has released a new eBook covering everything you need to know about PCR. This free resource is suitable for all user levels, from complete beginners starting out, all the way to experienced scientists who would simply like a skills refresh. The eBook features in-depth explanations, high-quality application notes and lots of helpful information to enable you to become a PCR pro in no time...

Scientists at the UK’s National Measurement Laboratory (NML) at LGC have published a paper, “Monkeypox: another test for PCR”, focusing on how to ensure the PCR diagnosis tests being deployed for monkeypox will be most accurate and that lessons learned on PCR testing from the COVID-19 pandemic are applied to the current epidemic. Dr Jim Huggett, Science Fellow at the NML, said, “Like the early stages of COVID-19, PCR is the only test that can be rapidly deployed to confirm Monkeypox cases....

New Application note from YMC - Fast UHPLC Analysis of Biomarkers Related to Tobacco Smoke Exposure using YMC-Triart C18 and YMC-Triart Diol-HILIC. Both RP and HILIC allow for high resolution peaks and fast separation. In addition to nicotine, the metabolite cotinine is also determined. The challenge here is that this is only detectable for a short time. NNAL, a breakdown product of the lung carcinogen NNK, is also suitable. In addition, human cells are exposed to oxidative stress when smoking...

Ziath has published a new catalogue that provides an informative technical introduction to its extensive range of innovative readers, scanners, software, automated tube selectors and accessories for tracking and management of life science samples. Over the last two decades, Ziath has established itself as a global leader for sample tracking of 2D barcoded tubes in applications including biobanking. compound management and COVID-19 patient sample management....

Hands-on cannabis testing! The market for cannabis products is expected to continue growing whilst requiring high quality equipment with excellent reproducibility for their complex analysis. In this whitepaper, the common challenges in cannabis testing by liquid chromatography are summarised. Numerous applications show how to select the ideal stationary phase for obtaining high resolution in cannabis potency testing excellent selectivity in pesticide analyses and sharp peak shapes in mycotoxin analyses...

The Froilabo CRP Blast Freezer is designed to rapidly freeze blood plasma in preparation for long term storage in ULT freezers. To preserve the quality and function of fresh frozen plasma (FFP) the freezing process must be rapid and homogeneous. During a Site Acceptance Test (SAT) the Froilabo CRP Blast Freezer was installed on a production line which processed plasma product. In this test, the aim was to verify the final temperature inside the plasma bags was -70°C...

A new 'Guide to Dry Down Solvent Evaporators' from Porvair Sciences offers an informative insight into traditional bottlenecks in chromatography sample preparation workflows and describes how blowdown evaporators work. Further the guide looks at factors that can enhance the speed and efficiency of sample dry down in microplates and vials and provides advice on how to choose the right evaporator for your laboratory....

Gilson has released the new 2022 Product Guide that contains their latest liquid handling, purification and extraction instruments which help make lab life easier. Gilson, who is a leading global manufacturer of sample management and purification technologies for the life sciences industry, have advanced their guide to be even more interactive and useful.  It has been designed to help signpost customers through to online tools and resources which will help them discover the right solutions for their applications....

With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A HT3 Headspace Analyzer will be used to examine bath salt samples for the presence of mephedrone (MPD) and methylenedioxypyrovalerone (MPDV or MDPK) by GC/MS.

YMC-Triart C18 UHPLC columns with an ID of 1 mm are the ideal choice for high sensitivity LC/MS analyses. In this new application note, the screening of 6 antineoplastic drugs is shown. This analysis requires the highest sensitivity since even the smallest amounts of these drugs need to be detected due to their adverse very serious, life-threatening effects. By choosing a high efficiency column with a small internal diameter of 1 mm and coupling it to mass spectrometry the benefit becomes clear: excellent peak shapes – also for low sensitivity compounds!

The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....

A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....

For decades, fluorescence microscopy has been an invaluable tool in life sciences research, with new variations and implementations emerging almost every year. Laser scanning microscopy, airyscanning, structured illumination, light field and light sheet microscopy are among the many methods that have been developed through the years to overcome the limitations of the original widefield microscopy setups...

Are you plagued with poor peak shapes, low sensitivities, sample carry over and/or low recoveries for challenging compounds. Several substances are able to interact with the usual inert column hardware materials such as stainless steel or titanium. The adsorption on metallic surfaces typically leads to peak tailing, loss of recovery and sample carry over. Critical substances are especially metal-coordinating compounds, such as fumonisins, sphingophospholipids or organophosphates in general....