TESTA Analytical reports a major polymer manufacturer is using their COMBO-ONE detector, as part of a GPC/SEC system, to characterize the structure of macromolecules that offer desirable performance properties. The client is a leading European manufacturer of high-performance water-soluble polymers for industrial applications. These polymers, although presenting a similar molecular weight and molecular weight distribution, have different physical structures which influence their performance in the target application...
TESTA Analytical has released an updated version of its HPLC Pump Qualification Pack designed for regulated labs looking to qualify the operation and performance of their HPLC systems. Version 1.4 of the popular HPLC Pump Qualification Pack includes a series of updates that make the tool more flexible and audit ready. Improvements include a new Pump Validation Checklist to guide users through the validation process step by step, ensuring a structured workflow thereby reducing the chance of errors...
TESTA Analytical reports that its Differential Refractometer improves the precision of dn/dc determination using light scattering techniques. An accurate dn/dc value is essential in molecular weight determination of biopolymers and polymers by light scattering. Backed by decades of experience of Gel Permeation Chromatography (GPC) and Light Scattering techniques, Testa Analytical has created a differential refractometer accessory for light scattering instruments that deliver exceptional performance and is easy-to-use...
Using the HPLC Pump Qualification Pack from TESTA Analytical considerably reduces the time required for HPLC pump qualification, while improving traceability of results. Comprising a calibrated non-invasive, realtime LC flowmeter, data validation tool and tablet-computer with pre-installed software – the pack automatically performs all necessary flow data calculations plus operational and performance qualification checks...
Flow rate is one of the most important parameters in any liquid chromatography system, it determines retention time or volume and therefore has a major influence on reproducibility. In this new study, the TESTA Analytical Liquid Chromatography Flowmeter is shown to provide a valuable tool for continuous, non-invasive measurement of flow rate in GPC/SEC systems...
FlowChrom from TESTA Analytical is an automated non-invasive, real-time monitoring system providing a continuous digital record of your HPLC system performance. While most HPLC and UHPLC are designed to operate 24/7, it is common for issues to arise when liquid chromatography systems are left unattended. In many instances, it is then difficult to understand what the source of the operating problem was and to determine when it occurred and how many HPLC separations were affected and must therefore be repeated...
TESTA Analytical has launched the HPLC Pump Qualification Pack - an efficient, fast, and reliable tool for regulated laboratories looking to qualify the operation and performance of their HPLC systems. Using the HPLC Pump Qualification Pack considerably reduces the time required for HPLC pump qualification, while improving traceability of results. By focusing on data traceability and simplifying the qualification process, this new all-in-one pack is an affordable solution for laboratories seeking to...
The Prep Flowmeter from TESTA Analytical is a new compact device for continuous monitoring of preparative HPLC purification and downstream processing systems. Preparative liquid chromatography is a trusted method for applications including purification of chiral drugs, fingerprinting of peptides, proteins, oligonucleotides, and purification of fine chemicals.Capable of precise monitoring of liquid flow rates of up to 650ml / minute in real time...
A new report ‘Validating HPLC results obtained using any solvent’ includes results from real time flow rate monitoring of an HPLC system using the LC Flowmeter from TESTA Analytical. Accurate flow rate data measurement is demonstrated for a wide range of HPLC solvents. This capability means the LC Flowmeter not only can be used for determination of solvent specific calibration factors, but will also allow scientists to generate absolutely correct flow rate data for almost any HPLC application...
TESTA Analytical reports how its liquid chromatography flowmeter is helping a leading German analytical services company to regularly qualify the operation and performance of their HPLC systems. A scientist at the analytical services company commented “We have a total of three HPLC systems that require regular and reliable qualification in accordance with current regulations to make them suitable for use in customer GLP, GCP and GMP projects...
TESTA Analytical reports how a German customer is using its GPC/SEC system to monitor the specifications of incoming raw materials. Historically due to variability in the quality of its raw materials, the customer found that a percentage of their final product (aminoplastic resins) had to be discarded for not fulfilling the expected specifications. Working with TESTA Analytical they have established strict QC routines on incoming materials using the GPC/SEC system...
ParSEC Advanced software from TESTA Analytical is designed to acquire and analyze data from Gel Permeation Chromatography / Size Exclusion Chromatography (GPC /SEC) systems fitted with any combination of refractive index, light scattering, UV, and viscosity detectors. Traditionally the complexity of data acquisition, storage, visualization, analysis, and reporting...
TESTA Analytical has published a new technical study that demonstrates the utility of its non-invasive liquid flowmeter for validating the performance of HPLC systems across a wide range of different solvents. HPLC separation protocols employ many different solvents to accommodate the unique properties of different analytes. Ensuring consistent elution profiles is a key requirement to ensure reproducible results...
TESTA Analytical reports, after extensive testing, that its high-precision HPLC flowmeter has been approved by one of the most prestigious Metrology Institutes in Beijing, China. Scientists at this pioneering national statutory authority in the field of metrology, investigated the HPLC flowmeter as a modern alternative to the traditional Flow calibration method for HPLC pumps (National Metrology Verification Regulations of the People's Republic of China JJG705-2014 Liquid Chromatography)...
TESTA Analytical announce Trinity – a powerful new triple detector for Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC). Triple Detection GPC/SEC is a gold standard technique for the complete and accurate characterization of macromolecules including proteins, polysaccharides, and synthetic polymers. Most often the technique combines both light scattering and viscometer detectors with a refractive index (RI) detector to deliver invaluable molecular weight and structure information to researchers...
A successful speciality chromatography detector development needs a partner who can understand the specific chromatographic needs of the target application and transform these needs into a high-quality tailored solution. Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solutions has proven itself as a highly effective speciality Liquid Chromatography detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide...
TESTA Analytical report how its COMBO-TWO MALS/DRI combination detector for Gel Permeation Chromatography (GPC) is helping biopharmaceutical and advanced materials researchers unlock essential macromolecular physical properties including molecular weight, structure, and conformation. The baseline signal stability of any GPC detector is important, as it is a limiting factor in peak determination. Combining a high-performance 7-angle Multi-Angle Light Scattering...
Refractive Index detectors are widely used for the analysis of molecules with weak or no UV absorption. TESTA Analytical’s Differential Refractive Index (DRI) Kit for HPLC can be adapted to almost any HPLC system to create a high performance instrument that separates and delivers sensitive detection of ‘RI active’ materials including alcohols, sugars, saccharides, fatty acids and polymers...
TESTA Analytical offers a choice of certification services to demonstrate the reliability and quality of each Liquid Chromatography flowmeter or microflowmeter it delivers to a customer lab. All flowmeters come with a free Certificate of Conformity demonstrating compliance of each individual device with the company’s published performance specifications. This certification is typically sufficient for any application involving constant monitoring of flow rate...
TESTA Analytical offer a range of Differential Refractive Index (DRI) detectors designed and proven to enhance the performance of almost any GPC/SEC, HPLC or UHPLC system. Measuring the refractive index of an analyte relative to the solvent – a high-performance Differential Refractive Index (DRI) detector is widely acknowledged as one of the most flexible detectors for liquid chromatography use...
TESTA Analytical reports on how its flowmeter software driver for chromatography data systems (CDS) has successfully passed extensive testing in a regulated pharmaceutical laboratory environment. Thorough testing of new software packages and drivers are nowadays an integral part of any new product release. This testing gains even higher importance when the software to be released is designed to operate flawlessly with chromatography software packages from different HPLC and GPC/SEC manufacturers...
TESTA Analytical announce new 21CFR Part 11 compliance software for use with its popular family of NanoBrook particle sizing and zeta potential instrumentation. Determination of particle size and zeta potential are widely used measurement techniques for quality control of materials in sectors such as the pharmaceutical industry which are tightly regulated and highly audited. In such environments – quality control techniques have to comply with a wide range of laws and guidelines by providing detailed documentation about the whole process...
TESTA Analytical announce a powerful new software driver that allows control and collection of data from any of its AB-4XXXX Series liquid flowmeters using a chromatography data system (CDS) which supports the Agilent Technologies rapid control framework (rc.NET). Software developer – Carlo Dessy said “Including real-time flow rate data with each chromatogram is a valuable aid to achieving total quality assessment of any HPLC, UHPLC, LC/MS or GPC/SEC system...
The COMBO-ONE Viscometer/DRI detector from TESTA Analytical sets a new standard for demanding GPC/SEC applications such as those focused on investigating the structure and branching of polymers. Viscometry detectors for GPC/SEC, based on four matched capillary tubes arranged in a manner analogous to a Wheatstone bridge, have been around for decades but have operational and performance shortfalls...
The BI-MwA Multi-Angle Light Scattering (MALS) detector from TESTA Analytical is proven to dramatically increase the capability of any GPC/SEC system to precisely determine the molecular weights of polymers and nanomaterials in solution. Additionally, if you are looking to determine absolute molecular weights of polysaccharides, proteins, and peptides or their aggregates by HPLC or uHPLC quickly and accurately, then look no further.
TESTA Analytical Solutions e.K. announce a new software tool for its AB4000X range of flowmeters to enable labs to automatically validate the performance of HPLC, uHPLC and GPC/SEC pumps. The Pump Validation Software Suite has been designed to accept raw data generated by the TESTA Analytical flowmeter PC-App and perform all necessary flow calculations automatically. Using this powerful software tool - all data and parameters are automatically validated for fitness of use for validation and a summary report generated...
TESTA Analytical has published a study that demonstrates how their Solvent Line Monitor is a valuable monitoring device for safeguarding HPLC, flow chemistry or liquid dosing systems from the many problems caused by undissolved gas bubbles. Dissolved gas is known to impact the performance of peristaltic pumps. A common solution to address this problem with HPLC system, is to use a vacuum degasser on the inlet side of the pump...
The BI-MwA Multi-Angle Light Scattering (MALS) detector from TESTA Analytical offers the highest performance to price ratio of any light scattering system available for molecular weight determination. If you are looking to determine absolute molecular weights of polysaccharides, proteins, and peptides or their aggregates by HPLC or uHPLC quickly and accurately, then look no further...
The Liquid Chromatography Flowmeter (LCF) from TESTA Analytical is a real-time monitoring device for continuously measuring the performance of pumps serving HPLC and uHPLC systems. Traditionally the quality of analytical data from HPLC systems has been determined by periodic checks of a set of measured parameters. This unfortunately just gives you a snapshot of how your HPLC system is performing at a point in time and cannot assure the total quality of an application...
TESTA Analytical has launched a new PC App to expand its versatility and further simplify using their Solvent Line Monitor device. The intuitive PC App allows easy configuration of the device enabling users to set the required level of sensitivity for monitoring for the presence of undissolved gas bubbles that can affect the accuracy of any reagent dispensing pump...
Measuring the rate of addition of liquid reagents accurately is a critical consideration for many labs undertaking batch or flow chemistry reactions. When using peristaltic or piston pumps to add expensive chemicals or other fluids into a reaction, labs must ensure the rate of addition is both accurate and constant. For labs looking to improve reproducibility and yield from liquid phase chemical reactions -TESTA Analytical has developed the Chemistry flowmeter...
The COMBO-TWO Multi-Angle Light Scattering / Differential Refractive Index (MALS / DRI) detector package from TESTA Analytical brings together a perfectly matched combination of a high performance 7-angle MALS and an ultra-stable DRI detector - both designed to optimally operate using an integral 640nm light source. Delivering absolute molecular weight data from small to large molecules, MALS is recognised as a trusted GPC/SEC detection technique for polymer, protein, and polysaccharide applications...
The HK Series Differential Viscometer from TESTA Analytical offers labs using Gel Permeation Chromatography (GPC/SEC) the opportunity to upgrade their system performance with a new best-in-class detector. Traditionally GPC/SEC viscometers have been based upon measurement of differential pressure across a capillary network. Using a next generation HK Series Differential Viscometer, GPC/SEC system users can now dramatically reduce their experimental noise level and increase sensitivity by more than an order of magnitude...
TESTA Analytical Solutions e.K has expanded the capabilities of its rapid scanning UV Detector with a new flow cell designed for high temperature operation. The rugged flow cell employs fiber optic connections to the rapid scanning UV detector to enable it to be safely positioned up to 1 meter way from the high temperature process being monitored...
TESTA Analytical has developed a new Multiple Angle Light Scattering / Differential Refractive Index (MALS / DRI) combination detector package for more demanding Gel Permeation Chromatography (GPC/SEC) applications. Delivering absolute molecular weight data from small to large molecules, MALS has established itself as a tried and trusted GPC/SEC detection technique for polymer, protein, and polysaccharide applications...
Operating from room temperature up to 80° C, with high thermal stability, the TESTA Analytical Differential Refractive Index (DRI) detector offers highly accurate and reliable determination of absolute concentration and total mass balance in GPC/SEC applications. DRI detectors are the most commonly used GPC/SEC detectors because of their universal applicability; they do not require chromophores to be present in the analyte...
For labs looking to improve accuracy, reproducibility, and yield from liquid phase chemical reactions -TESTA Analytical Solutions e.K has developed the Chemistry flowmeter. Accurately measuring the rate of addition of liquid reagents is a critical consideration for many labs undertaking batch or flow chemistry reactions. When using peristaltic or piston pumps to add expensive chemicals or other fluids into a reaction, labs must ensure the rate of addition is both accurate and constant as part of quality control...
TESTA Analytical Solutions e.K. announce the AB-40004 microflowmeter (µFlowmeter) - a non-invasive device designed to provide continuous high precision measurement of low volume liquid flows. Optimized to operate over the flow range 0.001 to 80 µL/minute, with an unmatched high resolution of 1nl / minute, the µFlowmeter is the perfect tool for precise measurement of low flow rates ensuring the reliability of quantitative HPLC / Mass Spectrometry (LC/MS) measurements...
The Solvent Line Monitor from TESTA Analytical is a true plug-and-play addition to any HPLC system designed to detect when one or more of its pump solvent reservoirs are empty and automatically shut-off the system. Modern chromatography systems often include automation enabling them to achieve a high sample throughput which was unthinkable just a few years ago. This has led to many organizations reducing the number of lab personnel trained to run HPLC systems....
Testa Analytical has introduced version 1.4 of its flowmeter software for continuous monitoring of liquid flow from an analytical or preparative HPLC system, peristaltic pump, flow chemistry system or mass spectrometer. Operating in conjunction with the TESTA Liquid Chromatography flowmeter the easy-to-use PC software app enables fast, simple experimental set-up and provides full control of device settings including integration time and calibration factor....
Based on decades of experience in the chromatography field, TESTA Analytical Solutions e.K. has designed a Differential Refractive Index (DRI) detector kit adaptable to fulfil the specific demands of different HPLC system manufacturers. Despite their limited sensitivity, compared to other detectors such as UV or MS, the ability of DRI detectors to detect any analyte...
TESTA Analytical Solutions e.K has launched the Solvent Line Monitor – a programmable, high sensitivity device for detecting gas bubbles in HPLC, Ion chromatography and flow chemistry systems. Temperature, pressure, reagent concentration, shock or agitation are all common variables that reduce the saturation point of liquids, resulting in the formation of gas bubbles. Most liquid chromatography users will have experienced how gas bubbles can result in changes in retention times...
The BI-200SM goniometer from TESTA Analytical Solutions e.K has been designed to make it the finest instrument available for research applications of light scattering. Offering unmatched performance for both Static Light Scattering (SLS) and Dynamic Light Scattering (DLS) experiments the BI-200SM research goniometer is a precision instrument for undertaking exacting measurements. Favored by leading research groups around the world, the BI-200SM’s modularity makes system expansion simple...
Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solution is established as an OEM detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide. A new case study describes how development of novel rapid scanning UV and differential refractive index detectors is helping an industrial and laboratory monitoring solutions provider offer a market leading instrumental solution for monitoring of polymerization reactions....
TESTA Analytical Solutions e.K reports how a leading European manufacturer of Chromatography Instrumentation is using its Liquid Chromatography Flowmeter to further improve performance of their top notch HPLC Systems. Flow rate is a critical parameter in HPLC systems, it determines retention time or volume and therefore has a major influence on reproducibility. The TESTA Analytical Liquid Chromatography Flowmeter has set a new standard for non-invasive measurement of flow rate in HPLC, GPC/SEC and Ion chromatography systems....
Refractive Index detectors are widely used for the analysis of molecules with weak or no UV absorption. TESTA Analytical’s Differential Refractive Index (DRI) Kit for HPLC can be adapted to almost any HPLC system to create a high performance instrument that separates and delivers sensitive detection of ‘RI active’ materials including alcohols, sugars, sacharides, fatty acids and polymers...
The BI-MwA Multi-Angle Light Scattering (MALS) system from Testa Analytical Solutions e.K. is a high-performance detector for studying polymers and proteins in solution as well as investigating aggregation, oligomerization, and complex formation. If you are looking to determine absolute molecular weights of proteins and polymers quickly and accurately, then look no further....
For all static light scattering applications - dn/dc (the specific refractive index increment) is a crucial parameter for ensuring accurate and precise measurements of molecular weight. Developed and refined over many years -TESTA Analytical's cutting edge technology sets a benchmark for precise determination of the dn/dc of polymers and proteins. TESTA Analytical's powerful HK Series dn/dc refractor system may be used to make measurements in either static or dynamic mode...
The new 2022 version of TESTA Analytical’s liquid chromatography flowmeter allows users to now set the optimal integration time to suit different applications. For example - sampling data every 0.1 seconds is optimal for real-time monitoring of HPLC pump performance whereas sampling data every 10 seconds is best for absolute flow rate calibration...
Testa Analytical Solutions e.K reports on growing interest in OEM versions of its Differential Refractive Index (DRI) detector to enhance the performance of both HPLC and GPC/SEC systems. Charlotte Stentzler, Technical Manager of Testa Analytical said "We have invested in stock components to enable us to offer our high performance DRI detectors, made here in Germany, on short delivery times....
TESTA Analytical Solutions e.K has introduced new laser options for its HK Series differential refractometer to enable precise determination of specific refractive index increment (dn/dc) at the same wavelength as the light scattering application under investigation. Light scattering is a tried and trusted method for measuring molecular weight and therefore a widely used tool for analyzing biopolymers, polymers and proteins....
The new HK Series Differential Refractometer from Testa Analytical Solutions e.K sets a benchmark for precise determination of specific refractive index increment (dn/dc) - an important parameter for polymer and protein molecular weight determination using light scattering techniques. The specific refractive index increment (dn/dc) is one of the most underestimated parameters in material science...
TESTA Analytical Solutions e.K reports that its popular Liquid Chromatography Flowmeter is being used to determine accurate flow rate calibration data from HPLC pumps in just a few minutes. To maintain consistent accuracy of results, each and every HPLC pump needs calibration of the flow rate it delivers on a regular base. The traditional method of calibrating HPLC pump flow rate relies upon a gravimetric method...
The HK Series Differential Refractive Index (DRI) detector from TESTA Analytical has been shown to provide accurate and reliable measurement of the absolute concentration and total mass of protein in a sample. Quantifying the amount of protein is highly desirable before processing protein samples for isolation, separation and analysis using chromatographic techniques. Refractive index is one of the most commonly used detectors in GPC/SEC and HPLC systems...
TESTA Analytical Solutions e.K. reports on widespread interest from European laboratories for performance qualifying their particle size, zeta potential and GPC/SEC instruments. The COVID-19 pandemic has had a huge effect on the daily operations of most laboratories. Restrictions concerning personnel on site has had a major impact on proven processes and standard operating procedures (SOP). As such, a new uncertainty has arisen about the qualification of measurement devices used for a particular application...
The new HK Series Multi Detector GPC/SEC System from TESTA Analytical Solutions e.K. combines high-performance chromatographic detector technologies and powerful, yet easy to use software to unlock the secrets of even the most complex synthetic polymers and natural macromolecules. Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) is widely accepted as the analytical technique of choice to characterize polymers and separate mixtures....
TESTA Analytical Solutions e.K reports how researchers at Lodz University of Technology (Poland) have combined the advanced analytical capabilities of its GPC/SEC triple detection system with a BI-200SM light scattering goniometer to derive in-depth information about an exciting new generation of polymer nanogels. Polymer nanogels with cross-linked structure provide a versatile platform for storage and release of biologically active compounds....
Testa Analytical Solutions e.K reports on the development and OEM supply of a novel combination refractive index / viscometry detector for Brookhaven Instruments Corporation (Holtsville, NY, USA). Polymer and plastics manufacturers offer very many different grades of commodity polymers such as poly(vinyl chloride), polyethylenes and polystyrenes. The Molecular Weight Distribution (MWD) of such polymers is a key item of information in tailoring their implementation for different end uses...
TESTA Analytical Solutions has published a technical report that evaluates an exciting new liquid flowmeter device designed to provide continuous real-time monitoring of the pump flow rate of any liquid chromatography system. High Performance Liquid Chromatography (HPLC) is nowadays one of the most widely used techniques in analytical chemistry. The range of applications soluble using HPLC covers a vast range of sample types, concentrations and compositions....
The Differential Refractive Index (DRI) detector from Testa Analytical Solution e.K offers unmatched accuracy and reliability for determination of absolute concentration and total mass balance in Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) applications. The baseline signal stability of any liquid chromatography detector is very important, as it is a limiting factor in peak determination....
TESTA Analytical Solutions e.K. has developed a new flowmeter which enables continuous measurement of flow rate without interference in chromatography systems. Flow rate is one of the most important parameters in any liquid chromatography system, it determines retention time or volume and has by nature a major influence on reproducibility. Compatible with all HPLC and GPC/SEC solvents, the new TESTA flowmeter is...
Testa Analytical Solutions e.K has published the first in a new series of online training presentations for scientists involved with, or interested in learning more about, Gel Permeation Chromatography (GPC). Gel Permeation Chromatography (GPC) is a type of Size Exclusion Chromatography (SEC), that separates analytes on the basis of size, typically in organic solvents. The technique is often used for the analysis of natural and synthetic polymers....
Testa Analytical Solutions e.K. has launched the new Particle Explorer software suite for its popular BI-200SM light scattering goniometer system. The new software suite has been designed to enable even occasional users to simply access the unmatched research grade performance and extensive operational versatility of the BI-200SM in one convenient user interface. All Particle Explorer software modules are easily accessible and packed with a plethora of new and exciting features....
Testa Analytical Solutions e.K, a leading developer of high-performance GPC / SEC instruments and detectors for polymer characterization will showcase its OEM design and manufacture capabilities at Analytica 2020. Backed by decades of experience, Testa Analytical has created, for a growing number of leading international laboratory and process instrument companies, fully optimised high-performance GPC/SEC detectors, GPC/SEC Pumps, accessories and software products customizable to meet their exact needs....
Testa Analytical Solutions reports on considerable interest from protein scientists to use Dynamic Light Scattering (DLS) as a tool for screening for the presence of aggregates as it is extremely sensitive to these larger compounds. Applications Lab Manager - Raffaele Carano said "Protein aggregation is a common challenge in the manufacturing of biological products. Protein scientists particularly like DLS because it provides them with a simple, fast and non-destructive test for aggregate detection....
If you have polymers or proteins, nanodots or new adhesives, latexes or liposomes, cosmetics or colloids, the Testa Analytical NanoBrook 90Plus is a perfect tool to characterize your particles. The 90Plus is designed to perform fast, routine submicron particle size measurements (<1 nm to 6 µm) on a wide variety of samples and concentrations. Based on the principles of dynamic light scattering, most measurements only take a minute or two...
Testa Analytical Solutions e.K is now offering optimized versions of its proprietary Differential Refractive Index (DRI) Detector under OEM contract to enhance the performance of both HPLC and GPC/SEC systems. arlo Dessy, Managing Director of Testa Analytical said "Our compact DRI Detector and DRI Detector Kits offer a wide range of options....
Testa Analytical Solutions e.K reports on the development and supply of key detector components for ACOMP, a smart manufacturing system by Fluence Analytics that continuously analyzes polymers during production. ACOMP is an automated monitoring system that produces real-time data about reaction kinetics and polymer properties, including....
Testa Analytical Solutions e.K announces a comprehensive new applications study that explains why making Dynamic Light Scattering (DLS) measurements in concentrated solutions is difficult. Dynamic Light Scattering is a widely used and effective technique for measuring the hydrodynamic size of common materials including colloids, nanoparticles, proteins, and polymers....
Testa Analytical Solutions e.K. reports on how a BI-200SM light scattering goniometer has been used to help assess the antimicrobial properties of silver and copper nanoparticles. In the study, various strains of Escherichia coli, Bacillus subtilis and Staphylococcus Aureus were treated with suspensions of suspended silver and copper nanoparticles....
Testa Analytical Solutions e.K reports that its BI-XDC X-Ray Disc Centrifuge is enabling scientists to make accurate, high resolution particle size distribution measurements, from nanometres to tens of micrometres, without time consuming calibration or absorption correction. Based on the principle of photosedimentation, the BI-XDC measures the size of particles according to the time the particle takes to sediment in...
Testa Analytical Solutions e.K reports on how a BI-200SM light scattering goniometer system with autocorrelator has helped researchers at a prestigious government laboratory to solve the enigma of why aqueous molybdenum solutions are blue. A spokesperson from the Department of Physics at the government laboratory said "Molybdenum and oxygen can combine to form a wide variety of structures, and some...
Testa Analytical Solutions e.K reports on how its NanoBrook Omni particle size analyser and BI-ZTU autotitrator can be used together to detect the onset of aggregation in nanoparticles. The NanoBrook Omni instrument offers a single powerful and accurate solution for particle sizing and zeta potential analysis. The instrument allows users to measure samples in nearly every possible suspension environment from high salts such as PBS and...
Testa Analytical Solutions e.K reports on a growing number of customers using their Nanobrook ZetaPALS instrument to accurately determine the size and surface charge of liposomes, exosomes and microvesicles. A new application note is available describing how the Nanobrook ZetaPALS instrument, using a phase analysis light scattering technique, has been used to accurately determine the size and surface charge of liposomes, exosomes and microvesicles....
Testa Analytical Solutions e.K reports that its Nanobrook ZetaPALS zeta potential analyser is uniquely optimised to make sensitive and precise measurements in both organic and aqueous media. Typically making zeta potential measurements in organic (non polar) solvents requires much higher sensitivity than in aqueous (polar) solutions. The Nanobrook ZetaPALS analyser achieves this using phase analysis light scattering...
Testa Analytical Solutions e.K. has added the AYE Differential Refractometer to its existing line of high-performance instruments for chromatographic measurements. The AYE is a flexible differential refractometer that may be used in either static or dynamic mode. In static mode, the specific refractive index increment (dn/dc) of dissolved samples can be easily and precisely determined in just a few minutes....
Testa Analytical Solutions e.K reports on how automation of isoelectric point measurement can be achieved using a BI-ZTU autotitrator in combination with a Nanobrook zeta potential analyzer. The stability of a dispersion is commonly determined by zeta potential. However, the surface chemistry of solid particles in a dispersion can be modified by altering parameters such as pH, surfactant concentration and salt concentrations....
Testa Analytical Solutions reports how the Institute of Applied Radiation Chemistry at the Lodz University of Technology (Poland) determined molecular weight and radius of gyration of polymeric microgels and nanogels by static multiangle laser light scattering (SLS) measurements using a BI-200SM goniometer. A nanogel is a two-component system of a diameter in the range of tens of nanometers, consisting of an intramolecularly crosslinked polymer chain...
Testa Analytical Solutions e.K. has introduced a Surface Zeta Potential option for its NanoBrook range of zeta potential analysers. Adding the new surface zeta potential option to a Nanobrook analyser allows you to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. The system uses known probe particles and purpose-designed electrode to calculate surface zeta potential. Leveraging proprietary phase analysis light scattering (PALS) technology...
Testa Analytical Solutions e.K. has introduced a Surface Zeta Potential option for its NanoBrook range of zeta potential analysers. Adding the new surface zeta potential option to a Nanobrook analyser allows you to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. The system uses known probe particles and purpose-designed electrode to calculate surface zeta potential....
Testa Analytical Solutions e.K has introduced a highly sensitive, online differential viscometer which can be used as part of a triple detector GPC/SEC system to determine the size and conformation of all types of synthetic polymers, biopolymers, proteins and peptides. Drawing upon over 30 years expertise, the new Testa Analytical detector incorporates technological innovations that dramatically reduce the noise level...
The NanoBrook ZetaPALS from Testa Analytical Solutions e.K is a highly accurate and easy-to-use Zeta Potential Analyzer using Phase Analysis Light Scattering. Based on the principle of phase analysis light scattering (PALS) – the Nanobrook ZetaPALS is designed for measuring electrophoretic mobilities. The Nanobrook ZetaPALS from...
The BI-MwA Molecular Weight Analyser from Testa Analytical Solutions e.K. is a high-performance tool for studying synthetic and natural polymers in solution as well as investigating protein aggregation, oligomerization, and complex formation. Employing a 30mW, 660 nm diode laser - the BI-MwA uses 7 angles to determine the intensity of scattered light as a function of angle and polymer concentration...
Testa Analytical Solutions now offers ReadyCal Calibration Kits – certified reference standards for organic and aqueous GPC/SEC applications. The colour coded ReadyCal standards come as polymer cocktails pre-weighed into 1.5ml autosampler vials for easy and convenient calibration of GPC/SEC experiments....
The Differential Refractive Index (DRI) Detector from Testa Analytical Solutions is a next-generation instrument for challenging GPC/SEC applications. The DRI Detector has been designed to fit seamlessly with all commercially available MALS and SLS detectors resulting in more accurate and reliable results. Its high sensitivity makes the Testa Analytical DRI Detector the perfect companion...
Testa Analytical Solutions e.K (Berlin, Germany) is taking the opportunity at ACHEMA 2018 to demonstrate its expertise in characterisation technologies for chemical and pharmaceutical manufacturers and research groups. ACHEMA is the leading chemical and process engineering exhibition that creates a forum for the exchange of ideas and new technology. Testa Analytical product specialists will be on hand in Hall 4.1, Stand K74 to discuss their...
The NanoBrook Omni from Testa Analytical Solutions combines leading edge particle sizing and zeta potential technology in one powerful and accurate instrument for particle and protein characterisation. Drawing upon high performance Dynamic Light Scattering (DLS) for particle sizing and distribution, and on Doppler Velocimetry....
TESTA Analytical reports a major polymer manufacturer is using their COMBO-ONE detector, as part of a GPC/SEC system, to characterize the structure of macromolecules that offer desirable performance properties. The client is a leading European manufacturer of high-performance water-soluble polymers for industrial applications. These polymers, although presenting a similar molecular weight and molecular weight distribution, have different physical structures which influence their performance in the target application...
TESTA Analytical has released an updated version of its HPLC Pump Qualification Pack designed for regulated labs looking to qualify the operation and performance of their HPLC systems. Version 1.4 of the popular HPLC Pump Qualification Pack includes a series of updates that make the tool more flexible and audit ready. Improvements include a new Pump Validation Checklist to guide users through the validation process step by step, ensuring a structured workflow thereby reducing the chance of errors...
TESTA Analytical reports that its Differential Refractometer improves the precision of dn/dc determination using light scattering techniques. An accurate dn/dc value is essential in molecular weight determination of biopolymers and polymers by light scattering. Backed by decades of experience of Gel Permeation Chromatography (GPC) and Light Scattering techniques, Testa Analytical has created a differential refractometer accessory for light scattering instruments that deliver exceptional performance and is easy-to-use...
Using the HPLC Pump Qualification Pack from TESTA Analytical considerably reduces the time required for HPLC pump qualification, while improving traceability of results. Comprising a calibrated non-invasive, realtime LC flowmeter, data validation tool and tablet-computer with pre-installed software – the pack automatically performs all necessary flow data calculations plus operational and performance qualification checks...
Flow rate is one of the most important parameters in any liquid chromatography system, it determines retention time or volume and therefore has a major influence on reproducibility. In this new study, the TESTA Analytical Liquid Chromatography Flowmeter is shown to provide a valuable tool for continuous, non-invasive measurement of flow rate in GPC/SEC systems...
FlowChrom from TESTA Analytical is an automated non-invasive, real-time monitoring system providing a continuous digital record of your HPLC system performance. While most HPLC and UHPLC are designed to operate 24/7, it is common for issues to arise when liquid chromatography systems are left unattended. In many instances, it is then difficult to understand what the source of the operating problem was and to determine when it occurred and how many HPLC separations were affected and must therefore be repeated...
TESTA Analytical has launched the HPLC Pump Qualification Pack - an efficient, fast, and reliable tool for regulated laboratories looking to qualify the operation and performance of their HPLC systems. Using the HPLC Pump Qualification Pack considerably reduces the time required for HPLC pump qualification, while improving traceability of results. By focusing on data traceability and simplifying the qualification process, this new all-in-one pack is an affordable solution for laboratories seeking to...
The Prep Flowmeter from TESTA Analytical is a new compact device for continuous monitoring of preparative HPLC purification and downstream processing systems. Preparative liquid chromatography is a trusted method for applications including purification of chiral drugs, fingerprinting of peptides, proteins, oligonucleotides, and purification of fine chemicals.Capable of precise monitoring of liquid flow rates of up to 650ml / minute in real time...
A new report ‘Validating HPLC results obtained using any solvent’ includes results from real time flow rate monitoring of an HPLC system using the LC Flowmeter from TESTA Analytical. Accurate flow rate data measurement is demonstrated for a wide range of HPLC solvents. This capability means the LC Flowmeter not only can be used for determination of solvent specific calibration factors, but will also allow scientists to generate absolutely correct flow rate data for almost any HPLC application...
TESTA Analytical reports how its liquid chromatography flowmeter is helping a leading German analytical services company to regularly qualify the operation and performance of their HPLC systems. A scientist at the analytical services company commented “We have a total of three HPLC systems that require regular and reliable qualification in accordance with current regulations to make them suitable for use in customer GLP, GCP and GMP projects...
TESTA Analytical reports how a German customer is using its GPC/SEC system to monitor the specifications of incoming raw materials. Historically due to variability in the quality of its raw materials, the customer found that a percentage of their final product (aminoplastic resins) had to be discarded for not fulfilling the expected specifications. Working with TESTA Analytical they have established strict QC routines on incoming materials using the GPC/SEC system...
ParSEC Advanced software from TESTA Analytical is designed to acquire and analyze data from Gel Permeation Chromatography / Size Exclusion Chromatography (GPC /SEC) systems fitted with any combination of refractive index, light scattering, UV, and viscosity detectors. Traditionally the complexity of data acquisition, storage, visualization, analysis, and reporting...
TESTA Analytical has published a new technical study that demonstrates the utility of its non-invasive liquid flowmeter for validating the performance of HPLC systems across a wide range of different solvents. HPLC separation protocols employ many different solvents to accommodate the unique properties of different analytes. Ensuring consistent elution profiles is a key requirement to ensure reproducible results...
TESTA Analytical reports, after extensive testing, that its high-precision HPLC flowmeter has been approved by one of the most prestigious Metrology Institutes in Beijing, China. Scientists at this pioneering national statutory authority in the field of metrology, investigated the HPLC flowmeter as a modern alternative to the traditional Flow calibration method for HPLC pumps (National Metrology Verification Regulations of the People's Republic of China JJG705-2014 Liquid Chromatography)...
TESTA Analytical announce Trinity – a powerful new triple detector for Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC). Triple Detection GPC/SEC is a gold standard technique for the complete and accurate characterization of macromolecules including proteins, polysaccharides, and synthetic polymers. Most often the technique combines both light scattering and viscometer detectors with a refractive index (RI) detector to deliver invaluable molecular weight and structure information to researchers...
A successful speciality chromatography detector development needs a partner who can understand the specific chromatographic needs of the target application and transform these needs into a high-quality tailored solution. Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solutions has proven itself as a highly effective speciality Liquid Chromatography detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide...
TESTA Analytical report how its COMBO-TWO MALS/DRI combination detector for Gel Permeation Chromatography (GPC) is helping biopharmaceutical and advanced materials researchers unlock essential macromolecular physical properties including molecular weight, structure, and conformation. The baseline signal stability of any GPC detector is important, as it is a limiting factor in peak determination. Combining a high-performance 7-angle Multi-Angle Light Scattering...
Refractive Index detectors are widely used for the analysis of molecules with weak or no UV absorption. TESTA Analytical’s Differential Refractive Index (DRI) Kit for HPLC can be adapted to almost any HPLC system to create a high performance instrument that separates and delivers sensitive detection of ‘RI active’ materials including alcohols, sugars, saccharides, fatty acids and polymers...
TESTA Analytical offers a choice of certification services to demonstrate the reliability and quality of each Liquid Chromatography flowmeter or microflowmeter it delivers to a customer lab. All flowmeters come with a free Certificate of Conformity demonstrating compliance of each individual device with the company’s published performance specifications. This certification is typically sufficient for any application involving constant monitoring of flow rate...
TESTA Analytical offer a range of Differential Refractive Index (DRI) detectors designed and proven to enhance the performance of almost any GPC/SEC, HPLC or UHPLC system. Measuring the refractive index of an analyte relative to the solvent – a high-performance Differential Refractive Index (DRI) detector is widely acknowledged as one of the most flexible detectors for liquid chromatography use...
TESTA Analytical reports on how its flowmeter software driver for chromatography data systems (CDS) has successfully passed extensive testing in a regulated pharmaceutical laboratory environment. Thorough testing of new software packages and drivers are nowadays an integral part of any new product release. This testing gains even higher importance when the software to be released is designed to operate flawlessly with chromatography software packages from different HPLC and GPC/SEC manufacturers...
TESTA Analytical announce new 21CFR Part 11 compliance software for use with its popular family of NanoBrook particle sizing and zeta potential instrumentation. Determination of particle size and zeta potential are widely used measurement techniques for quality control of materials in sectors such as the pharmaceutical industry which are tightly regulated and highly audited. In such environments – quality control techniques have to comply with a wide range of laws and guidelines by providing detailed documentation about the whole process...
TESTA Analytical announce a powerful new software driver that allows control and collection of data from any of its AB-4XXXX Series liquid flowmeters using a chromatography data system (CDS) which supports the Agilent Technologies rapid control framework (rc.NET). Software developer – Carlo Dessy said “Including real-time flow rate data with each chromatogram is a valuable aid to achieving total quality assessment of any HPLC, UHPLC, LC/MS or GPC/SEC system...
The COMBO-ONE Viscometer/DRI detector from TESTA Analytical sets a new standard for demanding GPC/SEC applications such as those focused on investigating the structure and branching of polymers. Viscometry detectors for GPC/SEC, based on four matched capillary tubes arranged in a manner analogous to a Wheatstone bridge, have been around for decades but have operational and performance shortfalls...
The BI-MwA Multi-Angle Light Scattering (MALS) detector from TESTA Analytical is proven to dramatically increase the capability of any GPC/SEC system to precisely determine the molecular weights of polymers and nanomaterials in solution. Additionally, if you are looking to determine absolute molecular weights of polysaccharides, proteins, and peptides or their aggregates by HPLC or uHPLC quickly and accurately, then look no further.
TESTA Analytical Solutions e.K. announce a new software tool for its AB4000X range of flowmeters to enable labs to automatically validate the performance of HPLC, uHPLC and GPC/SEC pumps. The Pump Validation Software Suite has been designed to accept raw data generated by the TESTA Analytical flowmeter PC-App and perform all necessary flow calculations automatically. Using this powerful software tool - all data and parameters are automatically validated for fitness of use for validation and a summary report generated...
TESTA Analytical has published a study that demonstrates how their Solvent Line Monitor is a valuable monitoring device for safeguarding HPLC, flow chemistry or liquid dosing systems from the many problems caused by undissolved gas bubbles. Dissolved gas is known to impact the performance of peristaltic pumps. A common solution to address this problem with HPLC system, is to use a vacuum degasser on the inlet side of the pump...
The BI-MwA Multi-Angle Light Scattering (MALS) detector from TESTA Analytical offers the highest performance to price ratio of any light scattering system available for molecular weight determination. If you are looking to determine absolute molecular weights of polysaccharides, proteins, and peptides or their aggregates by HPLC or uHPLC quickly and accurately, then look no further...
The Liquid Chromatography Flowmeter (LCF) from TESTA Analytical is a real-time monitoring device for continuously measuring the performance of pumps serving HPLC and uHPLC systems. Traditionally the quality of analytical data from HPLC systems has been determined by periodic checks of a set of measured parameters. This unfortunately just gives you a snapshot of how your HPLC system is performing at a point in time and cannot assure the total quality of an application...
TESTA Analytical has launched a new PC App to expand its versatility and further simplify using their Solvent Line Monitor device. The intuitive PC App allows easy configuration of the device enabling users to set the required level of sensitivity for monitoring for the presence of undissolved gas bubbles that can affect the accuracy of any reagent dispensing pump...
Measuring the rate of addition of liquid reagents accurately is a critical consideration for many labs undertaking batch or flow chemistry reactions. When using peristaltic or piston pumps to add expensive chemicals or other fluids into a reaction, labs must ensure the rate of addition is both accurate and constant. For labs looking to improve reproducibility and yield from liquid phase chemical reactions -TESTA Analytical has developed the Chemistry flowmeter...
The COMBO-TWO Multi-Angle Light Scattering / Differential Refractive Index (MALS / DRI) detector package from TESTA Analytical brings together a perfectly matched combination of a high performance 7-angle MALS and an ultra-stable DRI detector - both designed to optimally operate using an integral 640nm light source. Delivering absolute molecular weight data from small to large molecules, MALS is recognised as a trusted GPC/SEC detection technique for polymer, protein, and polysaccharide applications...
The HK Series Differential Viscometer from TESTA Analytical offers labs using Gel Permeation Chromatography (GPC/SEC) the opportunity to upgrade their system performance with a new best-in-class detector. Traditionally GPC/SEC viscometers have been based upon measurement of differential pressure across a capillary network. Using a next generation HK Series Differential Viscometer, GPC/SEC system users can now dramatically reduce their experimental noise level and increase sensitivity by more than an order of magnitude...
TESTA Analytical Solutions e.K has expanded the capabilities of its rapid scanning UV Detector with a new flow cell designed for high temperature operation. The rugged flow cell employs fiber optic connections to the rapid scanning UV detector to enable it to be safely positioned up to 1 meter way from the high temperature process being monitored...
TESTA Analytical has developed a new Multiple Angle Light Scattering / Differential Refractive Index (MALS / DRI) combination detector package for more demanding Gel Permeation Chromatography (GPC/SEC) applications. Delivering absolute molecular weight data from small to large molecules, MALS has established itself as a tried and trusted GPC/SEC detection technique for polymer, protein, and polysaccharide applications...
Operating from room temperature up to 80° C, with high thermal stability, the TESTA Analytical Differential Refractive Index (DRI) detector offers highly accurate and reliable determination of absolute concentration and total mass balance in GPC/SEC applications. DRI detectors are the most commonly used GPC/SEC detectors because of their universal applicability; they do not require chromophores to be present in the analyte...
For labs looking to improve accuracy, reproducibility, and yield from liquid phase chemical reactions -TESTA Analytical Solutions e.K has developed the Chemistry flowmeter. Accurately measuring the rate of addition of liquid reagents is a critical consideration for many labs undertaking batch or flow chemistry reactions. When using peristaltic or piston pumps to add expensive chemicals or other fluids into a reaction, labs must ensure the rate of addition is both accurate and constant as part of quality control...
TESTA Analytical Solutions e.K. announce the AB-40004 microflowmeter (µFlowmeter) - a non-invasive device designed to provide continuous high precision measurement of low volume liquid flows. Optimized to operate over the flow range 0.001 to 80 µL/minute, with an unmatched high resolution of 1nl / minute, the µFlowmeter is the perfect tool for precise measurement of low flow rates ensuring the reliability of quantitative HPLC / Mass Spectrometry (LC/MS) measurements...
The Solvent Line Monitor from TESTA Analytical is a true plug-and-play addition to any HPLC system designed to detect when one or more of its pump solvent reservoirs are empty and automatically shut-off the system. Modern chromatography systems often include automation enabling them to achieve a high sample throughput which was unthinkable just a few years ago. This has led to many organizations reducing the number of lab personnel trained to run HPLC systems....
Testa Analytical has introduced version 1.4 of its flowmeter software for continuous monitoring of liquid flow from an analytical or preparative HPLC system, peristaltic pump, flow chemistry system or mass spectrometer. Operating in conjunction with the TESTA Liquid Chromatography flowmeter the easy-to-use PC software app enables fast, simple experimental set-up and provides full control of device settings including integration time and calibration factor....
Based on decades of experience in the chromatography field, TESTA Analytical Solutions e.K. has designed a Differential Refractive Index (DRI) detector kit adaptable to fulfil the specific demands of different HPLC system manufacturers. Despite their limited sensitivity, compared to other detectors such as UV or MS, the ability of DRI detectors to detect any analyte...
TESTA Analytical Solutions e.K has launched the Solvent Line Monitor – a programmable, high sensitivity device for detecting gas bubbles in HPLC, Ion chromatography and flow chemistry systems. Temperature, pressure, reagent concentration, shock or agitation are all common variables that reduce the saturation point of liquids, resulting in the formation of gas bubbles. Most liquid chromatography users will have experienced how gas bubbles can result in changes in retention times...
The BI-200SM goniometer from TESTA Analytical Solutions e.K has been designed to make it the finest instrument available for research applications of light scattering. Offering unmatched performance for both Static Light Scattering (SLS) and Dynamic Light Scattering (DLS) experiments the BI-200SM research goniometer is a precision instrument for undertaking exacting measurements. Favored by leading research groups around the world, the BI-200SM’s modularity makes system expansion simple...
Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solution is established as an OEM detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide. A new case study describes how development of novel rapid scanning UV and differential refractive index detectors is helping an industrial and laboratory monitoring solutions provider offer a market leading instrumental solution for monitoring of polymerization reactions....
TESTA Analytical Solutions e.K reports how a leading European manufacturer of Chromatography Instrumentation is using its Liquid Chromatography Flowmeter to further improve performance of their top notch HPLC Systems. Flow rate is a critical parameter in HPLC systems, it determines retention time or volume and therefore has a major influence on reproducibility. The TESTA Analytical Liquid Chromatography Flowmeter has set a new standard for non-invasive measurement of flow rate in HPLC, GPC/SEC and Ion chromatography systems....
Refractive Index detectors are widely used for the analysis of molecules with weak or no UV absorption. TESTA Analytical’s Differential Refractive Index (DRI) Kit for HPLC can be adapted to almost any HPLC system to create a high performance instrument that separates and delivers sensitive detection of ‘RI active’ materials including alcohols, sugars, sacharides, fatty acids and polymers...
The BI-MwA Multi-Angle Light Scattering (MALS) system from Testa Analytical Solutions e.K. is a high-performance detector for studying polymers and proteins in solution as well as investigating aggregation, oligomerization, and complex formation. If you are looking to determine absolute molecular weights of proteins and polymers quickly and accurately, then look no further....
For all static light scattering applications - dn/dc (the specific refractive index increment) is a crucial parameter for ensuring accurate and precise measurements of molecular weight. Developed and refined over many years -TESTA Analytical's cutting edge technology sets a benchmark for precise determination of the dn/dc of polymers and proteins. TESTA Analytical's powerful HK Series dn/dc refractor system may be used to make measurements in either static or dynamic mode...
The new 2022 version of TESTA Analytical’s liquid chromatography flowmeter allows users to now set the optimal integration time to suit different applications. For example - sampling data every 0.1 seconds is optimal for real-time monitoring of HPLC pump performance whereas sampling data every 10 seconds is best for absolute flow rate calibration...
Testa Analytical Solutions e.K reports on growing interest in OEM versions of its Differential Refractive Index (DRI) detector to enhance the performance of both HPLC and GPC/SEC systems. Charlotte Stentzler, Technical Manager of Testa Analytical said "We have invested in stock components to enable us to offer our high performance DRI detectors, made here in Germany, on short delivery times....
TESTA Analytical Solutions e.K has introduced new laser options for its HK Series differential refractometer to enable precise determination of specific refractive index increment (dn/dc) at the same wavelength as the light scattering application under investigation. Light scattering is a tried and trusted method for measuring molecular weight and therefore a widely used tool for analyzing biopolymers, polymers and proteins....
The new HK Series Differential Refractometer from Testa Analytical Solutions e.K sets a benchmark for precise determination of specific refractive index increment (dn/dc) - an important parameter for polymer and protein molecular weight determination using light scattering techniques. The specific refractive index increment (dn/dc) is one of the most underestimated parameters in material science...
TESTA Analytical Solutions e.K reports that its popular Liquid Chromatography Flowmeter is being used to determine accurate flow rate calibration data from HPLC pumps in just a few minutes. To maintain consistent accuracy of results, each and every HPLC pump needs calibration of the flow rate it delivers on a regular base. The traditional method of calibrating HPLC pump flow rate relies upon a gravimetric method...
The HK Series Differential Refractive Index (DRI) detector from TESTA Analytical has been shown to provide accurate and reliable measurement of the absolute concentration and total mass of protein in a sample. Quantifying the amount of protein is highly desirable before processing protein samples for isolation, separation and analysis using chromatographic techniques. Refractive index is one of the most commonly used detectors in GPC/SEC and HPLC systems...
TESTA Analytical Solutions e.K. reports on widespread interest from European laboratories for performance qualifying their particle size, zeta potential and GPC/SEC instruments. The COVID-19 pandemic has had a huge effect on the daily operations of most laboratories. Restrictions concerning personnel on site has had a major impact on proven processes and standard operating procedures (SOP). As such, a new uncertainty has arisen about the qualification of measurement devices used for a particular application...
The new HK Series Multi Detector GPC/SEC System from TESTA Analytical Solutions e.K. combines high-performance chromatographic detector technologies and powerful, yet easy to use software to unlock the secrets of even the most complex synthetic polymers and natural macromolecules. Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) is widely accepted as the analytical technique of choice to characterize polymers and separate mixtures....
TESTA Analytical Solutions e.K reports how researchers at Lodz University of Technology (Poland) have combined the advanced analytical capabilities of its GPC/SEC triple detection system with a BI-200SM light scattering goniometer to derive in-depth information about an exciting new generation of polymer nanogels. Polymer nanogels with cross-linked structure provide a versatile platform for storage and release of biologically active compounds....
Testa Analytical Solutions e.K reports on the development and OEM supply of a novel combination refractive index / viscometry detector for Brookhaven Instruments Corporation (Holtsville, NY, USA). Polymer and plastics manufacturers offer very many different grades of commodity polymers such as poly(vinyl chloride), polyethylenes and polystyrenes. The Molecular Weight Distribution (MWD) of such polymers is a key item of information in tailoring their implementation for different end uses...
TESTA Analytical Solutions has published a technical report that evaluates an exciting new liquid flowmeter device designed to provide continuous real-time monitoring of the pump flow rate of any liquid chromatography system. High Performance Liquid Chromatography (HPLC) is nowadays one of the most widely used techniques in analytical chemistry. The range of applications soluble using HPLC covers a vast range of sample types, concentrations and compositions....
The Differential Refractive Index (DRI) detector from Testa Analytical Solution e.K offers unmatched accuracy and reliability for determination of absolute concentration and total mass balance in Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) applications. The baseline signal stability of any liquid chromatography detector is very important, as it is a limiting factor in peak determination....
TESTA Analytical Solutions e.K. has developed a new flowmeter which enables continuous measurement of flow rate without interference in chromatography systems. Flow rate is one of the most important parameters in any liquid chromatography system, it determines retention time or volume and has by nature a major influence on reproducibility. Compatible with all HPLC and GPC/SEC solvents, the new TESTA flowmeter is...
Testa Analytical Solutions e.K has published the first in a new series of online training presentations for scientists involved with, or interested in learning more about, Gel Permeation Chromatography (GPC). Gel Permeation Chromatography (GPC) is a type of Size Exclusion Chromatography (SEC), that separates analytes on the basis of size, typically in organic solvents. The technique is often used for the analysis of natural and synthetic polymers....
Testa Analytical Solutions e.K. has launched the new Particle Explorer software suite for its popular BI-200SM light scattering goniometer system. The new software suite has been designed to enable even occasional users to simply access the unmatched research grade performance and extensive operational versatility of the BI-200SM in one convenient user interface. All Particle Explorer software modules are easily accessible and packed with a plethora of new and exciting features....
Testa Analytical Solutions e.K, a leading developer of high-performance GPC / SEC instruments and detectors for polymer characterization will showcase its OEM design and manufacture capabilities at Analytica 2020. Backed by decades of experience, Testa Analytical has created, for a growing number of leading international laboratory and process instrument companies, fully optimised high-performance GPC/SEC detectors, GPC/SEC Pumps, accessories and software products customizable to meet their exact needs....
Testa Analytical Solutions reports on considerable interest from protein scientists to use Dynamic Light Scattering (DLS) as a tool for screening for the presence of aggregates as it is extremely sensitive to these larger compounds. Applications Lab Manager - Raffaele Carano said "Protein aggregation is a common challenge in the manufacturing of biological products. Protein scientists particularly like DLS because it provides them with a simple, fast and non-destructive test for aggregate detection....
If you have polymers or proteins, nanodots or new adhesives, latexes or liposomes, cosmetics or colloids, the Testa Analytical NanoBrook 90Plus is a perfect tool to characterize your particles. The 90Plus is designed to perform fast, routine submicron particle size measurements (<1 nm to 6 µm) on a wide variety of samples and concentrations. Based on the principles of dynamic light scattering, most measurements only take a minute or two...
Testa Analytical Solutions e.K is now offering optimized versions of its proprietary Differential Refractive Index (DRI) Detector under OEM contract to enhance the performance of both HPLC and GPC/SEC systems. arlo Dessy, Managing Director of Testa Analytical said "Our compact DRI Detector and DRI Detector Kits offer a wide range of options....
Testa Analytical Solutions e.K reports on the development and supply of key detector components for ACOMP, a smart manufacturing system by Fluence Analytics that continuously analyzes polymers during production. ACOMP is an automated monitoring system that produces real-time data about reaction kinetics and polymer properties, including....
Testa Analytical Solutions e.K announces a comprehensive new applications study that explains why making Dynamic Light Scattering (DLS) measurements in concentrated solutions is difficult. Dynamic Light Scattering is a widely used and effective technique for measuring the hydrodynamic size of common materials including colloids, nanoparticles, proteins, and polymers....
Testa Analytical Solutions e.K. reports on how a BI-200SM light scattering goniometer has been used to help assess the antimicrobial properties of silver and copper nanoparticles. In the study, various strains of Escherichia coli, Bacillus subtilis and Staphylococcus Aureus were treated with suspensions of suspended silver and copper nanoparticles....
Testa Analytical Solutions e.K reports that its BI-XDC X-Ray Disc Centrifuge is enabling scientists to make accurate, high resolution particle size distribution measurements, from nanometres to tens of micrometres, without time consuming calibration or absorption correction. Based on the principle of photosedimentation, the BI-XDC measures the size of particles according to the time the particle takes to sediment in...
Testa Analytical Solutions e.K reports on how a BI-200SM light scattering goniometer system with autocorrelator has helped researchers at a prestigious government laboratory to solve the enigma of why aqueous molybdenum solutions are blue. A spokesperson from the Department of Physics at the government laboratory said "Molybdenum and oxygen can combine to form a wide variety of structures, and some...
Testa Analytical Solutions e.K reports on a growing number of customers using their Nanobrook ZetaPALS instrument to accurately determine the size and surface charge of liposomes, exosomes and microvesicles. A new application note is available describing how the Nanobrook ZetaPALS instrument, using a phase analysis light scattering technique, has been used to accurately determine the size and surface charge of liposomes, exosomes and microvesicles....
Testa Analytical Solutions e.K reports that its Nanobrook ZetaPALS zeta potential analyser is uniquely optimised to make sensitive and precise measurements in both organic and aqueous media. Typically making zeta potential measurements in organic (non polar) solvents requires much higher sensitivity than in aqueous (polar) solutions. The Nanobrook ZetaPALS analyser achieves this using phase analysis light scattering...
Testa Analytical Solutions e.K. has added the AYE Differential Refractometer to its existing line of high-performance instruments for chromatographic measurements. The AYE is a flexible differential refractometer that may be used in either static or dynamic mode. In static mode, the specific refractive index increment (dn/dc) of dissolved samples can be easily and precisely determined in just a few minutes....
Testa Analytical Solutions reports how the Institute of Applied Radiation Chemistry at the Lodz University of Technology (Poland) determined molecular weight and radius of gyration of polymeric microgels and nanogels by static multiangle laser light scattering (SLS) measurements using a BI-200SM goniometer. A nanogel is a two-component system of a diameter in the range of tens of nanometers, consisting of an intramolecularly crosslinked polymer chain...
Testa Analytical Solutions e.K. has introduced a Surface Zeta Potential option for its NanoBrook range of zeta potential analysers. Adding the new surface zeta potential option to a Nanobrook analyser allows you to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. The system uses known probe particles and purpose-designed electrode to calculate surface zeta potential. Leveraging proprietary phase analysis light scattering (PALS) technology...
Testa Analytical Solutions e.K. has introduced a Surface Zeta Potential option for its NanoBrook range of zeta potential analysers. Adding the new surface zeta potential option to a Nanobrook analyser allows you to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. The system uses known probe particles and purpose-designed electrode to calculate surface zeta potential....
Testa Analytical Solutions e.K has introduced a highly sensitive, online differential viscometer which can be used as part of a triple detector GPC/SEC system to determine the size and conformation of all types of synthetic polymers, biopolymers, proteins and peptides. Drawing upon over 30 years expertise, the new Testa Analytical detector incorporates technological innovations that dramatically reduce the noise level...
The NanoBrook ZetaPALS from Testa Analytical Solutions e.K is a highly accurate and easy-to-use Zeta Potential Analyzer using Phase Analysis Light Scattering. 
The BI-MwA Molecular Weight Analyser from Testa Analytical Solutions e.K. is a high-performance tool for studying synthetic and natural polymers in solution as well as investigating protein aggregation, oligomerization, and complex formation. 
Testa Analytical Solutions now offers ReadyCal Calibration Kits – certified reference standards for organic and aqueous GPC/SEC applications. 
The Differential Refractive Index (DRI) Detector from Testa Analytical Solutions is a next-generation instrument for challenging GPC/SEC applications. 
Testa Analytical Solutions e.K (Berlin, Germany) is taking the opportunity at ACHEMA 2018 to demonstrate its expertise in characterisation technologies for chemical and pharmaceutical manufacturers and research groups. ACHEMA is the leading chemical and process engineering exhibition that creates a forum for the exchange of ideas and new technology. Testa Analytical product specialists will be on hand in Hall 4.1, Stand K74 to discuss their...
The NanoBrook Omni from Testa Analytical Solutions combines leading edge particle sizing and zeta potential technology in one powerful and accurate instrument for particle and protein characterisation. Drawing upon high performance Dynamic Light Scattering (DLS) for particle sizing and distribution, and on Doppler Velocimetry....