A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Elsevier, a global leader in scientific information and data analytics, releases an alpha version of Scopus AI for researcher testing – a next generation tool that combines generative AI with Scopus' trusted content and data to help researchers get deeper insights faster, support collaboration and societal impact of research. For more than a decade, Elsevier has been using AI and machine learning technologies responsibly in its products combined with its unparalleled peer-reviewed content, extensive data sets, and sophisticated analytics...
California Seed and Plant (CSP) Labs, a leading private plant pathology and genetics testing laboratory in California, is using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes from INTEGRA Biosciences to streamline its nucleic acid extraction and sample processing workflows. These 24, 96 and 384 channel pipettes are used to help assess seed, plant and soil health with greater efficiency and reproducibility, supporting innovations in the agricultural industry to keep up with rising global food demands...
The automation of laboratories used to be considered very costly and not very flexible, because the workflows are very complex and amounts of data are constantly increasing. Yet, as chemical and pharmaceutical industry product lifecycles become shorter and shorter, the need for digitalization has become urgent. In this article, Christof Franzke, Senior Technical Consultant Key Accounts at COPA-DATA, the industrial software specialist, explains the vital role of the zenon platform in the roll-out of modularization and digitalization in laboratories...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast Series on Wednesday, August 9, with Why We Love LIMS: ATL Customers Tell Their LIMS Success Stories. Feedback from webcast attendees has always been very positive when we invite ATL LIMS clients to share their views on how a LIMS has become an essential component of their laboratory operations...
Scientists and engineers at the National Physical Laboratory (NPL)are working with colleagues at the Science and Technology Facilities Council’s (STFC) RAL Space to deliver a small satellite calibration facility. The new facility is being designed, manufactured and tested at NPL’s Teddington site in south-west London and will be located at Harwell Campus. It will draw on expertise from NPL’s STAR-cc-OGSE facility, which provides innovative solutions for calibrating scientific instruments on satellites before their launch into space...
A £5 million award from the UK Space Agency will allow Northumbria University to take forward world-leading research to build a new satellite communications system, setting the scene for Northumbria to launch the UK’s first university-led multi-satellite space mission. The funding announcement made today allow the University to move forward with its prototype work on this new laser-based system, which has the potential to transform the satellite communications industry...
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), has announced the five founding members of the Alliance for Genomic Discovery (AGD). The multiyear agreement aims to accelerate development of therapeutics through large-scale genomics and the establishment of a preeminent clinical genomic resource...
Despite recommendations from the European Society for Medical Oncology and the EU Beating Cancer Plan, uptake of next-generation sequencing (NGS) in lung cancer remains slow and inequitable across Europe. In the first report of its kind, experts highlight action needed to correct disparity in access to a gold-standard diagnostic technology that could benefit tens of thousands of lung cancer patients across Europe every year...
In 2022, raw sewage was pumped into English rivers and seas for 1.75 million hours, or 200 cumulative years. Despite awareness of the need for environmental safeguarding growing every year, UK waterways still suffer pollution of the foulest kind. And it isn’t only sewage that waste companies have to worry about: here Matt Allen, product manager for elemental analysers at SciMed, the UK’s largest distributor of lab equipment, explains why testing water for halogen species will be a serious consideration in the near future...
Discovery Park, in Sandwich, Kent has launched a new business support programme and competition, ‘Discovery Spark’. Discovery Spark is currently accepting applications from life-science start-ups, with a closing deadline of 20 August. From the first cohort of up to 12 companies, one business will be selected to win a prize package worth over £100,000, including £50,000 investment from Discovery Park Ventures, 1 year of free lab space at Discovery Park, plus wrap-around business support and dedicated mentoring...
Researchers are set to to combine expertise in drug discovery, artificial intelligence (AI), and experimental cancer models and platforms in a new programme to design the precision cancer drugs of the future. Under an academic and commercial collaboration between The Institute of Cancer Research, London, the Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, and the company Vivan Therapeutics, a multi-disciplijnary team will seek to create drugs that can counteract drug resistance...
NK:IO, a leader in NK cell biology applied to the development of exceptionally potent, off-the-shelf cell therapies targeting solid tumours, has announced it has been awarded £1.6M in grant funding from Innovate UK’s New Cancer Therapeutics program. The funding will support preclinical development, including development of a manufacturing process in collaboration with the Cell and Gene Therapy Catapult, whose mission is to support the UK’s cell and gene therapy industry...
Merck, has awarded Khalid Salaita, Samuel Candler Dobbs Professor in the Department of Chemistry at Emory University, Atlanta, Georgia, U.S.A., with the Future Insight Prize 2023 worth € 500,000 for research on a pandemic early alert system. Salaita’s group is developing a novel platform technology for automated surveillance and tracing of airborne pathogens in real time...
Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published findings of a new impartial investigation into the impact of using pre-poured Petri dishes from different suppliers for air sampling in cleanroom environmental monitoring (EM) programmes. This extends Cherwell’s initial ‘plate choice’ investigation which found that size and form factor of plates can affect microbial air sampling accuracy...
AMSBIO has published a blog about Dr. Satoshi Okamoto’s groundbreaking research on the production of induced pluripotent stem cells (iPSC)-derived liver organoids, and their significant potential in clinical research trials. The primary objective of Dr. Okamoto's research program at the Yokohama City University Graduate School's Department of Regenerative Medicine was to achieve large-scale, stable production of clinical-grade liver organoids...
Researchers from the Ebisuya Group at EMBL Barcelona have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development differs substantially across animals...
The Center for Emerging Viral Threats (CEVT) in Louisiana, USA, is using INTEGRA Biosciences’ liquid handling solutions for COVID-19 testing and viral genomics studies. These products have streamlined the center’s sample transfer protocols, leading to shorter turnaround times and supporting vital research into the prevention and control of viral respiratory diseases. The CEVT was established in March 2020 to address the urgent testing needs caused by the COVID-19 pandemic...
VitaDAO, the global community accelerating research and development in longevity science, is pleased to announce the launch of the VITA-FAST tokens. This marks the first-ever opportunity for token holders to directly influence longevity research, setting a new precedent in the field of decentralized science (DeSci). The VITA-FAST tokens, which allow holders to make decisions on IP licensing, set experiment priorities, and govern research on autophagy, have been met with overwhelming interest...
The European Molecular Biology Laboratory (EMBL) and ZEISS have entered a long-term strategic partnership. The collaboration aims to close the gap between early-stage imaging technology development and its application in life science research. Through this collaborative approach, users of the EMBL Imaging Centre and related EMBL imaging services will have access to the latest microscopy technologies and expertise from ZEISS...
LAUDA DR. R. WOBSER GMBH & CO. KG is working with the Institute for Drive Technology (IAA) at the University Aalen to develop a PHM (Prognostics and Health Management) system for AI-based status monitoring of constant temperature equipment at automotive test stations. The project has received 424,000 euros in financial support from the Baden-Württemberg Ministry of Economic Affairs, Labor and Tourism through the InvestBW funding program...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Elsevier, a global leader in scientific information and data analytics, releases an alpha version of Scopus AI for researcher testing – a next generation tool that combines generative AI with Scopus' trusted content and data to help researchers get deeper insights faster, support collaboration and societal impact of research. For more than a decade, Elsevier has been using AI and machine learning technologies responsibly in its products combined with its unparalleled peer-reviewed content, extensive data sets, and sophisticated analytics...
California Seed and Plant (CSP) Labs, a leading private plant pathology and genetics testing laboratory in California, is using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes from INTEGRA Biosciences to streamline its nucleic acid extraction and sample processing workflows. These 24, 96 and 384 channel pipettes are used to help assess seed, plant and soil health with greater efficiency and reproducibility, supporting innovations in the agricultural industry to keep up with rising global food demands...
The automation of laboratories used to be considered very costly and not very flexible, because the workflows are very complex and amounts of data are constantly increasing. Yet, as chemical and pharmaceutical industry product lifecycles become shorter and shorter, the need for digitalization has become urgent. In this article, Christof Franzke, Senior Technical Consultant Key Accounts at COPA-DATA, the industrial software specialist, explains the vital role of the zenon platform in the roll-out of modularization and digitalization in laboratories...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast Series on Wednesday, August 9, with Why We Love LIMS: ATL Customers Tell Their LIMS Success Stories. Feedback from webcast attendees has always been very positive when we invite ATL LIMS clients to share their views on how a LIMS has become an essential component of their laboratory operations...
Scientists and engineers at the National Physical Laboratory (NPL)are working with colleagues at the Science and Technology Facilities Council’s (STFC) RAL Space to deliver a small satellite calibration facility. The new facility is being designed, manufactured and tested at NPL’s Teddington site in south-west London and will be located at Harwell Campus. It will draw on expertise from NPL’s STAR-cc-OGSE facility, which provides innovative solutions for calibrating scientific instruments on satellites before their launch into space...
A £5 million award from the UK Space Agency will allow Northumbria University to take forward world-leading research to build a new satellite communications system, setting the scene for Northumbria to launch the UK’s first university-led multi-satellite space mission. The funding announcement made today allow the University to move forward with its prototype work on this new laser-based system, which has the potential to transform the satellite communications industry...
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), has announced the five founding members of the Alliance for Genomic Discovery (AGD). The multiyear agreement aims to accelerate development of therapeutics through large-scale genomics and the establishment of a preeminent clinical genomic resource...
Despite recommendations from the European Society for Medical Oncology and the EU Beating Cancer Plan, uptake of next-generation sequencing (NGS) in lung cancer remains slow and inequitable across Europe. In the first report of its kind, experts highlight action needed to correct disparity in access to a gold-standard diagnostic technology that could benefit tens of thousands of lung cancer patients across Europe every year...
In 2022, raw sewage was pumped into English rivers and seas for 1.75 million hours, or 200 cumulative years. Despite awareness of the need for environmental safeguarding growing every year, UK waterways still suffer pollution of the foulest kind. And it isn’t only sewage that waste companies have to worry about: here Matt Allen, product manager for elemental analysers at SciMed, the UK’s largest distributor of lab equipment, explains why testing water for halogen species will be a serious consideration in the near future...
Discovery Park, in Sandwich, Kent has launched a new business support programme and competition, ‘Discovery Spark’. Discovery Spark is currently accepting applications from life-science start-ups, with a closing deadline of 20 August. From the first cohort of up to 12 companies, one business will be selected to win a prize package worth over £100,000, including £50,000 investment from Discovery Park Ventures, 1 year of free lab space at Discovery Park, plus wrap-around business support and dedicated mentoring...
Researchers are set to to combine expertise in drug discovery, artificial intelligence (AI), and experimental cancer models and platforms in a new programme to design the precision cancer drugs of the future. Under an academic and commercial collaboration between The Institute of Cancer Research, London, the Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, and the company Vivan Therapeutics, a multi-disciplijnary team will seek to create drugs that can counteract drug resistance...
NK:IO, a leader in NK cell biology applied to the development of exceptionally potent, off-the-shelf cell therapies targeting solid tumours, has announced it has been awarded £1.6M in grant funding from Innovate UK’s New Cancer Therapeutics program. The funding will support preclinical development, including development of a manufacturing process in collaboration with the Cell and Gene Therapy Catapult, whose mission is to support the UK’s cell and gene therapy industry...
Merck, has awarded Khalid Salaita, Samuel Candler Dobbs Professor in the Department of Chemistry at Emory University, Atlanta, Georgia, U.S.A., with the Future Insight Prize 2023 worth € 500,000 for research on a pandemic early alert system. Salaita’s group is developing a novel platform technology for automated surveillance and tracing of airborne pathogens in real time...
Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published findings of a new impartial investigation into the impact of using pre-poured Petri dishes from different suppliers for air sampling in cleanroom environmental monitoring (EM) programmes. This extends Cherwell’s initial ‘plate choice’ investigation which found that size and form factor of plates can affect microbial air sampling accuracy...
AMSBIO has published a blog about Dr. Satoshi Okamoto’s groundbreaking research on the production of induced pluripotent stem cells (iPSC)-derived liver organoids, and their significant potential in clinical research trials. The primary objective of Dr. Okamoto's research program at the Yokohama City University Graduate School's Department of Regenerative Medicine was to achieve large-scale, stable production of clinical-grade liver organoids...
Researchers from the Ebisuya Group at EMBL Barcelona have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development differs substantially across animals...
The Center for Emerging Viral Threats (CEVT) in Louisiana, USA, is using INTEGRA Biosciences’ liquid handling solutions for COVID-19 testing and viral genomics studies. These products have streamlined the center’s sample transfer protocols, leading to shorter turnaround times and supporting vital research into the prevention and control of viral respiratory diseases. The CEVT was established in March 2020 to address the urgent testing needs caused by the COVID-19 pandemic...
VitaDAO, the global community accelerating research and development in longevity science, is pleased to announce the launch of the VITA-FAST tokens. This marks the first-ever opportunity for token holders to directly influence longevity research, setting a new precedent in the field of decentralized science (DeSci). The VITA-FAST tokens, which allow holders to make decisions on IP licensing, set experiment priorities, and govern research on autophagy, have been met with overwhelming interest...
The European Molecular Biology Laboratory (EMBL) and ZEISS have entered a long-term strategic partnership. The collaboration aims to close the gap between early-stage imaging technology development and its application in life science research. Through this collaborative approach, users of the EMBL Imaging Centre and related EMBL imaging services will have access to the latest microscopy technologies and expertise from ZEISS...
LAUDA DR. R. WOBSER GMBH & CO. KG is working with the Institute for Drive Technology (IAA) at the University Aalen to develop a PHM (Prognostics and Health Management) system for AI-based status monitoring of constant temperature equipment at automotive test stations. The project has received 424,000 euros in financial support from the Baden-Württemberg Ministry of Economic Affairs, Labor and Tourism through the InvestBW funding program...