Orbitrap Fusion Tribrid LC-MS technology to power new cellular signaling network research  

Thermo Fisher Scientific and  the Department of Systems Biology at the Technical University of Denmark, (DTU), have formed a collaboration to pursue breakthroughs in the understanding of how cellular protein networks drive important diseases. Under the collaboration, Thermo Fisher will provide early access to new technology and designs, and DTU proteomics scientists will provide feedback and collaborate on new applications...

A new article detailing a round table discussion on quality by design (QbD) authored by leading industry experts including Spinnovation  Biologics CEO Frederic Girard is now available online.

Entitled ‘QbD and PAT in Upstream and Downstream Processing’, the article details the fundamental principles of QbD, how it is used to improve process control, and the impact technological advances have made on QbD biopharmaceutical upstream process optimization. Originally published in the July addition of Biopharm International the full article is now available to read...

Analytik, leading suppliers of innovative analytical solutions to the UK and Ireland, report on the application of the ASD, a PANalytical company, LabSpec 4 portable Vis-NIR spectrometer in the characterisation of samples at the National Soil Resources Institute at Cranfield University.

The National Soil Resources Institute is located at Cranfield University where it leads the University's research on soil science to better understand the physical, chemical and biological processes that make up soil systems and provide the capacity for soil-based ecosystem services. Dr Abdul Mounem Mouazen has a background in the application of engineering principles to soil and water management, with specific applications in soil dynamics, tillage, traction, compaction, mechanical weeding, soil remediation and management...

Thermo Fisher Scientific has developed a simple and accurate method to quantify four key antibiotics in dried distillers grains with solubles (DDGS) using high-performance liquid chromatography with charged aerosol detection.

Application Note (AN) 1055: Determination of Virginiamycin, Erythromycin, and Penicillin in Dried Distillers Grains with Solubles demonstrates the ability of a specialized protein and peptide column to efficiently separate and resolve the target antibiotics within 15 min, followed by column cleanup and equilibration for a total analysis time of 25 min. The U.S. Food and Drug Administration has raised concern over food-producing animals consuming DDGS with antibiotic residues, which potentially may lead to increased antibiotic resistance in humans and animals...

Analytik Jena UK will be celebrating the 50^th anniversary of the SPECORD^® range of spectrophotometers at the Lab Innovations exhibition by showing the SPECORD^® 210 Plus double beam UV/Vis instrument. The multi N/C 3100 and the multi N/C UV HS TOC analysers will also be on show, reflecting the fact that the company also has decades of experience in this field of analysis.

The Oasis Tool Recommends Optimized Protocols Customized to Customer's Samples

Waters Corporation (NYSE: WAT) today unveiled its new web-based Oasis® Method Development Tools designed to help customers reduce their sample preparation method development time as part of Waters Simple Prep™ campaign. Based on the customers’ sample requirements, the Oasis Method Development Tools will recommend the optimized solid-phase extraction (SPE) protocol to develop robust methods with high recovery for liquid chromatography and mass spectrometry applications...

SPECTRO Analytical UK will showcase the new SPECTROBLUE TI inductively coupled plasma optical emission spectrometer (ICP-OES) at Lab Innovations 2013 (6 - 7 November 2013, National Exhibition Centre, Birmingham, UK).

This innovative system extends the company’s SPECTROBLUE ICP-OES product line, offering automatic dual plasma observation. This optimizes linearity and dynamic range, while enabling high-sensitivity measurement of toxic elements, which makes it especially suitable for environmental analyses. While matrix effects are drastically reduced, it can accurately determine levels of alkali/earth alkali elements in complex alkali matrices....

Visit Spectro Analytical on stand number A23

Bruker introduces two new instruments which further expand its portfolio of high-performance tools for materials characterization in electron microscopes

J.G. Finneran Associates, an industry leader in high quality chromatography vials and accessories, manufactures headspace vials and closures to the same high quality standards.

J.G. Finneran manufactures their line of headspace vials from only Type I borosilicate glass for durability, heat resistance and low extraction.  Available in either clear glass or amber glass for light sensitive samples.  The vial’s wide opening allow for samples to be easily added, and all 20mL headspace vials are available with a marking spot.

Porvair will officially launch the UltraVap Mistral robot-compatible automatic dry down station at Drug  Discovery 2013 (Manchester, UK) and Biotechnica 2013 (Hannover, Germany)

Drawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry downstep into your automated liquid handling protocol.  The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a new “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling.

Advanced Chromatography Technologies Limited has launched two new Ultra-Inert phases for method development; ACE C18-Amide and ACE CN-ES. These products incorporate the latest developments in UHPLC/HPLC stationary phase design and provide chromatographers with new choices for alternative selectivity, without compromising stability or robustness.

VICI Valco’s Cheminert Model M6 and M50 Liquid Handling Pumps are a new generation of pumps for precision handling of liquids and/or gases, producing a bidirectional pulseless flow with a range of over six orders of magnitude (5 nL/min to 5 mL/min for the M6 Pump; 1 µL/min to 25 mL/min for the M50 Pump).

An excellent replacement for syringe pumps, the Cheminert pumps offer better performance and eliminate the need for refill cycles and syringe changes. The M6 and M50 are positive displacement pumps, which means they are self-priming and tolerant of any gas which may find its way into the fluid lines. There is no separate fill cycle, and the capacity is unlimited. RS-232 and RS-485 communication protocols are incorporated into the microprocessor-driven controller. (USB interface requires an adapter.) The included software package controls flow rates, flow direction and metered volumes...

Once a James Bond fantasy, diamond-based lasers are now becoming a reality.

Ground-breaking research is harnessing the unique properties of diamonds to develop a new generation of lasers that could lead to many benefits, from better treatment of skin complaints and diabetes-related eye conditions to improved pollution monitoring and aeronautical engineering. A University of Strathclyde team has developed a new type of high-performance, ultra-versatile Raman laser* that harnesses diamonds to produce light beams with more power and a wider range of colours than current Raman lasers...

Torrey Pines Scientific announces its new EchoTherm™ HPLC Column Heater Model CO20. 

The temperature range is from room temperature to 90.0°C readable and settable to 0.1°C.  The PID temperature control software regulates temperatures to ±0.1°C.  Temperature accuracy and stability are ±0.1ºC with a stable temperature indicator lamp on the front panel that lights when the target temperature is stable to within ±0.2ºC. The unit holds columns up to 30 cm long by ¼” or 3/8” diameter in mounting clips provided with room for guard columns and fittings. Larger diameter columns can be used by removing the column clips that hold the smaller columns...

Ocean Optics STS spectrometers measure vegetation from the ground and the air

A pair of super-lightweight miniature spectrometers from Ocean Optics is helping researchers investigate plant parameters in a verdant patch of New Zealand grassland. The compact STS model spectrometers, one deployed as a ground unit and the other aboard an unmanned aerial vehicle (UAV), are making synchronized hyperspectral measurements of barley and sugar beet crops to assess plant characteristics for more effective crop management...

Thermo Fisher Scientific is pleased to announce a new technical note on fast separations in a carbonated beverage using increased flow rates on our high-pressure capillary Ion Chromatography (IC) system, the Thermo Scientific Dionex ICS-5000+ Reagent Free HPIC system.

Technical Note 118: Fast Separations of Anions and Organic Acids in a Carbonated Beverage Using High-Pressure Capillary IC describes the determinations of organic acids in these carbonated beverages. The beverage industry uses these acidulants and flavoring agents to maintain beverage freshness, to minimize microbiological growth and to add a characteristic flavor...

Thermo Fisher Scientific Inc. introduces new pH gradient buffer solutions designed to save time in method development and facilitate method transfer to QA/QC for a wide range of MAb charge variants using an HPLC system.

Unlike traditional salt gradients, the new Thermo Scientific buffers enable users to predict the pH and retention times of charge variants and use a narrow pH range to produce higher resolution separations. The solutions and kits are designed to deliver highly-reproducible, linear pH gradients in cation exchange chromatography for MAbs, proteins and biosimilars. Thermo Fisher Scientific offers a large portfolio of bioseparations consumables and instruments, including MAbPac and ProPac cation exchange columns...

ACE C18-Amide is a new, uniquely designed UHPLC/HPLC stationary phase offering improved retention of polar compounds, enhanced phenolic resolution and alternative selectivity to C18 bonded columns.

The unique ligand design of the ACE C18-Amide incorporates an extended alkyl chain spacer between the silica surface and amide polar group, which gives extra phase stability in eluents of pH 2 - pH 8.  The longer C18 tail increases the hydrophobic mechanism of interaction compared to phases with shorter (C14 - C16) tail groups...

Thermo Fisher Scientific has developed a high-performance liquid chromatography (HPLC) method for a fast and sensitive determination of paraquat and diquat in tap and environmental water samples.

This approach uses on-line solid phase extraction (SPE) and achieves method detection limits that meet the requirements of both U.S. Environmental Protection Agency Method 549.2 and European Union 98/83/EC. Application Note (AN) 1051: Sensitive and Rapid Determination of Paraquat and Diquat in Tap and Environmental Water demonstrates use of a mixed-mode column to provide sufficient retention, excellent resolution, and good peak shape for these herbicides...

Thermo Fisher Scientific Expands Water Purification Portfolio 

Thermo Fisher Scientific Inc., the world leader in serving science, has launched the Thermo Scientific Barnstead GenPure xCAD Plus water purification system, featuring advanced technology that allows simultaneous dispensing from three remote dispensers for exceptional flexibility and ease of use in shared laboratory environments. Additionally, the company announced enhancements to its existing systems...

With the NIRS DS2500, near infrared analysis has taken yet another step into the future of routine analysis. The NIRS DS2500 Analyzer offers exceptional accuracy across a broad wavelength range and is designed for use in the receiving area or at-line of a variety of industries ranging from nutraceuticals and pharmaceuticals to chemicals and others.

The new predispersive monochromator technology used in the NIRS DS2500 ensures versatility and stability across the full spectral range from 400 to 2’500 nm. In less than a minute, with the highest possible signal-to-noise ratio, the NIRS DS2500 can effortlessly manage analysis of demanding and low level parameters in need of high accuracy....

Xmark Media the organisers of Photonex 2013, the UK's showcase photonics conference & exhibition announce the programme and speakers for the meeting on Nano and Bio-Imaging. This FREE-to-attend conference will be held on Wednesday 16^th October as part of a diverse two-day event at the visitor-friendly Ricoh Arena in Coventry.

Significant advances in the development of optical techniques have led to an inter-disciplinary use of photonics in the study of various problems in the life sciences, in biological and chemical sciences, in medicine, clinical sciences, neurophysiology etc. Researchers are continually looking for better ways to analyse complex processes....