The Maulide Group at the University of Vienna (Austria) describe how a devastating water leak in a nearby chemistry laboratory prompted them to search for alternative, water-free, options to Liebig condensers for refluxing. The group teamed up with Green Labs Austria to see if they could provide and share a more sustainable solution to water cooled refluxing in the lab....
The moisture determination of liquid soap is essential to ensure a product of the highest quality. If the moisture content is too high or too low, this can result in a low quality product and wastage can occur. In this application note we determine the moisture of liquid soap using Precisa’s XM60/EM120 Halogen moisture analyser...
In 2021, Eppendorf AG, the Hamburg life sciences company, is presenting its highly prestigious research prize for the 26th time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn announced Dr. Tanmay Bharat, Sir William Dunn School of Pathology, University of Oxford, United Kingdom as the winner of the Eppendorf Award for European Investigators 2021....
HORIBA announces its participation in a new consortium formed to accelerate the development of process analytical technologies (PAT) in cell and gene therapy manufacturing. HORIBA’s new A-TEEM™ Molecular Fingerprinting technology has shown great promise for fast QC/QA of complex biological systems and is a core technology being assessed for reducing batch failures and manufacturing costs, to enable faster time to market....
108Labs, a biotechnology and software company with a mission to invent disruptive cellular agriculture projects, has announced their focus on building and programming the world’s first autonomous Cellufacturing® facility and artificial intelligence platform for the production of cell-cultured human milk, in the birthplace of biosynthetic human milk, Hillsborough, North Carolina....
Binding Site is pleased to announce that the ground-breaking iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) study has reached an important milestone, with the publication of a paper outlining the design and recruitment of this population-based screening study. The large-scale study – which includes over 80,000 individuals, more than half of the eligible population of Iceland...
Leading Drug Discovery Contract Research Organisation Sygnature Discovery has announced the set-up of a state-of-the-art Early Candidate Developability Screening Group. Located at its headquarters in Nottingham, UK, the new service line will expand on the company’s offerings to customers by bridging into formal preclinical drug development and paving the way for clinical trials...
Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumours have faulty copies of the BRCA cancer genes. The drugs, known as POLQ inhibitors, specifically kill cancer cells with mutations in the BRCA genes while leaving healthy cells unharmed. And crucially, they can kill cancer cells that have become resistant to PARP inhibitors – an existing treatment for patients with BRCA mutations....
As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
Australian National Phenome Centre Integrates Quantitative NMR and MS Assay Platform for Risk Assessment and Longitudinal Monitoring of Post-Acute COVID-19 Syndrome (PACS). A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase...
A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles. The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery....
Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature. However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...
The Native Antigen Company, part of LGC Clinical Diagnostics and one of the world’s leading suppliers of reagents that enables research into diagnostics and vaccines for emerging and endemic infectious diseases, won ‘The Best COVID-19 Responder’ at OBN 2020 Awards. The award recognises the Company’s outstanding contribution to the fight against COVID-19....
Glasgow-based R-Biopharm Rhône (RBR), a business which manufactures and distributes test kits for the analysis of foodstuffs for a diverse range of constituents and potential contaminants, has joined the elite ranks of UK businesses accredited with the Investors in People (IIP) Platinum award. The company, employing 60 people at its West of Scotland Science Park base in the north west of the city, is one of the UK’s most successful exporters in its field...
ENPICOM, an innovative bioinformatics software engineering company, announce the upcoming expansion of the IGX Platform’s capabilities towards advanced liability prediction. At the Antibody Engineering and Therapeutics virtual conference, the company revealed its plans to integrate the Structural Antibody Prediction Platform (SAbPred) developed by researchers at the University of Oxford....
Thermo Fisher Scientific, the world leader in serving science, and the University of Sheffield, a leading institution with a global reputation for research excellence, have joined forces to develop advanced end-to-end workflows for the characterization and monitoring of complex oligonucleotide and mRNA products. This collaboration brings together the University of Sheffield’s extensive research expertise and Thermo Fisher’s cutting-edge sample preparation, liquid chromatography....
In this article, the characterization of lactose powders for use in DPI applications is discussed. We present new results obtained from state-of-the-art characterization methods allowing us to gather insightful information on the powder behavior. Moreover, electrostatic properties which are of great interest for DPI applications in particular with respect to drug release from the lactose carrier are investigated....
INTEGRA Biosciences has made significant progress towards its goal of minimizing its ecological footprint with the installation of new photovoltaic systems at the company’s US facilities in Hudson, NH. These systems will provide 77 percent of the total energy requirement for both the company’s US headquarters and production center, saving as much CO2 as 2900 cars or 2300 single-family homes produce in the USA each year....
As a project company of Xlife Sciences AG (XLS DE), inflamed pharma GmbH has developed a revolutionary and holistic therapeutic approach to treat both SARS-CoV-2 and flu viruses. The patented active substance ProcCluster(R) reduces the viral load by 90% and acts against infection-related inflammatory processes without developing a resistance. It is already used on humans...
Largest reported organ-on-a-chip screen ever performed on a 3D angiogenesis assay. MIMETAS, the global leader in human-relevant organ-on-a-chip models, has just opened their Phenotypic Screening Center. The center facilitates large-scale screening campaigns on Organ-on-a-Chip models, a powerful technology that improves the human physiological relevance of cultured tissues by utilizing microfluidic techniques....
Thermo Fisher Scientific, the world leader in serving science, and Newomics, a commercial-stage biotechnology company, are collaborating to develop a novel native liquid chromatography-mass spectrometry (LC−MS) platform to support various LC−MS applications. This agreement utilizes Newomics’ experience in creating innovative and integrative platforms and solutions for precision medicine and Thermo Fisher’s cutting-edge LC-MS systems...
Aptamer Group Limited, the developer of Optimer™ Therapeutics, and PinotBio (Gyeonggi-do, Korea), a clinical-stage oncology-focused biotechnology company, have entered into a strategic collaboration agreement. The agreement is to develop Optimer-drug conjugates for targeted drug delivery combining Aptamer Group’s Optimer technology with PinotBio’s technology using the chemotherapeutic FL-118 compound with specific linker....
The Maulide Group at the University of Vienna (Austria) describe how a devastating water leak in a nearby chemistry laboratory prompted them to search for alternative, water-free, options to Liebig condensers for refluxing. The group teamed up with Green Labs Austria to see if they could provide and share a more sustainable solution to water cooled refluxing in the lab....
The moisture determination of liquid soap is essential to ensure a product of the highest quality. If the moisture content is too high or too low, this can result in a low quality product and wastage can occur. In this application note we determine the moisture of liquid soap using Precisa’s XM60/EM120 Halogen moisture analyser...
In 2021, Eppendorf AG, the Hamburg life sciences company, is presenting its highly prestigious research prize for the 26th time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn announced Dr. Tanmay Bharat, Sir William Dunn School of Pathology, University of Oxford, United Kingdom as the winner of the Eppendorf Award for European Investigators 2021....
HORIBA announces its participation in a new consortium formed to accelerate the development of process analytical technologies (PAT) in cell and gene therapy manufacturing. HORIBA’s new A-TEEM™ Molecular Fingerprinting technology has shown great promise for fast QC/QA of complex biological systems and is a core technology being assessed for reducing batch failures and manufacturing costs, to enable faster time to market....
108Labs, a biotechnology and software company with a mission to invent disruptive cellular agriculture projects, has announced their focus on building and programming the world’s first autonomous Cellufacturing® facility and artificial intelligence platform for the production of cell-cultured human milk, in the birthplace of biosynthetic human milk, Hillsborough, North Carolina....
Binding Site is pleased to announce that the ground-breaking iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) study has reached an important milestone, with the publication of a paper outlining the design and recruitment of this population-based screening study. The large-scale study – which includes over 80,000 individuals, more than half of the eligible population of Iceland...
Leading Drug Discovery Contract Research Organisation Sygnature Discovery has announced the set-up of a state-of-the-art Early Candidate Developability Screening Group. Located at its headquarters in Nottingham, UK, the new service line will expand on the company’s offerings to customers by bridging into formal preclinical drug development and paving the way for clinical trials...
Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumours have faulty copies of the BRCA cancer genes. The drugs, known as POLQ inhibitors, specifically kill cancer cells with mutations in the BRCA genes while leaving healthy cells unharmed. And crucially, they can kill cancer cells that have become resistant to PARP inhibitors – an existing treatment for patients with BRCA mutations....
As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
Australian National Phenome Centre Integrates Quantitative NMR and MS Assay Platform for Risk Assessment and Longitudinal Monitoring of Post-Acute COVID-19 Syndrome (PACS). A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase...
A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles. The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery....
Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature. However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...
The Native Antigen Company, part of LGC Clinical Diagnostics and one of the world’s leading suppliers of reagents that enables research into diagnostics and vaccines for emerging and endemic infectious diseases, won ‘The Best COVID-19 Responder’ at OBN 2020 Awards. The award recognises the Company’s outstanding contribution to the fight against COVID-19....
Glasgow-based R-Biopharm Rhône (RBR), a business which manufactures and distributes test kits for the analysis of foodstuffs for a diverse range of constituents and potential contaminants, has joined the elite ranks of UK businesses accredited with the Investors in People (IIP) Platinum award. The company, employing 60 people at its West of Scotland Science Park base in the north west of the city, is one of the UK’s most successful exporters in its field...
ENPICOM, an innovative bioinformatics software engineering company, announce the upcoming expansion of the IGX Platform’s capabilities towards advanced liability prediction. At the Antibody Engineering and Therapeutics virtual conference, the company revealed its plans to integrate the Structural Antibody Prediction Platform (SAbPred) developed by researchers at the University of Oxford....
Thermo Fisher Scientific, the world leader in serving science, and the University of Sheffield, a leading institution with a global reputation for research excellence, have joined forces to develop advanced end-to-end workflows for the characterization and monitoring of complex oligonucleotide and mRNA products. This collaboration brings together the University of Sheffield’s extensive research expertise and Thermo Fisher’s cutting-edge sample preparation, liquid chromatography....
In this article, the characterization of lactose powders for use in DPI applications is discussed. We present new results obtained from state-of-the-art characterization methods allowing us to gather insightful information on the powder behavior. Moreover, electrostatic properties which are of great interest for DPI applications in particular with respect to drug release from the lactose carrier are investigated....
INTEGRA Biosciences has made significant progress towards its goal of minimizing its ecological footprint with the installation of new photovoltaic systems at the company’s US facilities in Hudson, NH. These systems will provide 77 percent of the total energy requirement for both the company’s US headquarters and production center, saving as much CO2 as 2900 cars or 2300 single-family homes produce in the USA each year....
As a project company of Xlife Sciences AG (XLS DE), inflamed pharma GmbH has developed a revolutionary and holistic therapeutic approach to treat both SARS-CoV-2 and flu viruses. The patented active substance ProcCluster(R) reduces the viral load by 90% and acts against infection-related inflammatory processes without developing a resistance. It is already used on humans...
Largest reported organ-on-a-chip screen ever performed on a 3D angiogenesis assay. MIMETAS, the global leader in human-relevant organ-on-a-chip models, has just opened their Phenotypic Screening Center. The center facilitates large-scale screening campaigns on Organ-on-a-Chip models, a powerful technology that improves the human physiological relevance of cultured tissues by utilizing microfluidic techniques....
Thermo Fisher Scientific, the world leader in serving science, and Newomics, a commercial-stage biotechnology company, are collaborating to develop a novel native liquid chromatography-mass spectrometry (LC−MS) platform to support various LC−MS applications. This agreement utilizes Newomics’ experience in creating innovative and integrative platforms and solutions for precision medicine and Thermo Fisher’s cutting-edge LC-MS systems...
Aptamer Group Limited, the developer of Optimer™ Therapeutics, and PinotBio (Gyeonggi-do, Korea), a clinical-stage oncology-focused biotechnology company, have entered into a strategic collaboration agreement. The agreement is to develop Optimer-drug conjugates for targeted drug delivery combining Aptamer Group’s Optimer technology with PinotBio’s technology using the chemotherapeutic FL-118 compound with specific linker....