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High-Throughput Method for Simultaneous Analysis of Water-Soluble Vitamins

Thermo Fisher Scientific has developed a high-throughput method for the simultaneous analysis of water-soluble vitamins (WSVs) in multivitamin supplements and vitamin-enriched beverages.

Application Note 294: Simultaneous Analysis of Water-Soluble Vitamins in Vitamin-Enriched Beverages and Multivitamin Dietary Supplements by UHPLC-MS/MSThe ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method described in Application Note 294: Simultaneous Analysis of Water-Soluble Vitamins in Vitamin-Enriched Beverages and Multivitamin Dietary Supplements by UHPLC-MS/MS was optimized for total resolution of all target analytes on a reversed-phase (RP) C30 column with a rapid separation LC (RSLC) system and a triple stage quadrupole mass spectrometer. Accurate quantitative measurements for vitamins are required to ensure product quality and regulatory compliance as well as to monitor vitamin intake.

This method demonstrated excellent, precision, accuracy, and selective and sensitive detection with low quantitation limits and a high correlation of determination, and was successfully applied to the determination of WSVs in beverages and supplement tablets.

This application note and many others can be found at www.thermoscientific.com/dionex under the Documents tab.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of $12 billion, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and UnityTM Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity.

All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries. Please note links are current at time of issuance.


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