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Practical Guidelines for Capillary Anion-Exchange Chromatography

Practical Guidance for Using Capillary Anion ChromatographyThermo Fisher Scientific is pleased to announce a technical note describing procedures and practices that help chromatographers get the most out of their capillary ion-chromatography system. Technical Note 113: Practical Guidance for Using Capillary Anion Chromatography presents tips and techniques that will help ensure that good chromatographic results are obtained as system volumes are reduced for capillary IC.

Capillary ion chromatography (IC), which separates ions using 0.4 mm diameter columns at 10-30 μL/min flow rates, provides increased mass sensitivity, reduces water consumption, and reduces waste generation to only ~5 L per year. The increased mass sensitivity is ideal for samples of limited amount and for trace analysis. To achieve these benefits, some additional care
is required to maintain flat ends on tubing, to prevent gaps between tubing and connectors, and to prevent air bubbles from being trapped in the capillary system. TN 113 describes techniques for plumbing and flushing the system, and procedures for performing trace analyses, including direct large loop injections and concentrator column installation and loading.

This technical note and many others can be found at www.thermoscientific.com/dionex under the Documents tab.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of $12 billion, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and UnityTM Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity.

All trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries.


 

 

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