Search News Archives
Follow us on
Conferences | Events

Media Partners

 

JPK Reports on the Retrovirus Research of Professor Itay Rousso and his Colleagues at Ben-Gurion University in Israel Using the NanoWizard ULTRA Speed AFM

publication date: Jan 30, 2018
 | 
author/source: JPK Instruments AG

JPK Ben Gurion U users - Rousso  Rankovic

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the ground-breaking research into the understanding of the reproduction of retroviruses such as HIV at Ben-Gurion University in Beer-Sheba, Israel.

This research uses JPK's NanoWizard® ULTRA Speed AFM. 

Professor Itay Rousso leads a research group in the Department of Physiology and Cell Biology at Ben-Gurion University in Beer Sheba. Their focus is to uncover the physical mechanism underlying the replication machinery of enveloped retroviruses (primarily HIV). So far, they have studied the assembly and budding steps, viral entry and during the past three years, they have been studying the mechanism that triggers core disassembly and release of the viral genome – a process termed uncoating. 

In the opinion of Professor Rousso, one of the major advantages of the AFM is its ability to study “live” samples under physiological environments with spatial resolution similar to that of the EM. This ability enables investigating dynamic processes as well as characterization of samples under native environments. His team studies specimens at sizes of 80-100 nm, which is well within the resolution limit of the AFM, which allow the investigation of viral associated process with sufficient resolution. Presently, the questions they investigate can hardly be addressed using other techniques. 

With experience of different commercial systems, Dr Rousso talks about why the JPK system offers particularly helpful capabilities. “For us, the JPK system can provide some of the more advanced features such as quantitative imaging mode, QI™, and fast-scanning imaging. The main benefits in using JPK AFM system are that (1) JPK is a company which provides a direct link to their development team. This enables more flexibility in our work, e.g. we often use non-conventional measurements which we can consult and even obtain some custom modifications; and (2) the open architecture design of the JPK operating system basically provides the user with the ability to customize nearly every parameter and perform measurements and experiments as required.” 

The Rousso group have published a number of papers using the JPK NanoWizard® AFM to study the mechanical and morphological properties of HIV-1 capsids. These illustrate the NanoWizard®'s versatility, resolution and high performance imaging.1-3 

For more details about JPK’s AFM systems and their applications for the materials, life & nano sciences, please visit the web site.


more about JPK instruments


more news from JPK instruments


 


If you have not logged into the website then please enter your details below.



 

Popular this Month

 

Chromatography in Cannabis Testing

 

New Catalogue of Infectious Disease Antibodies and Antigens

 

Acquisition of B&W Tek takes Metrohm’s Spectroscopy Portfolio to the Next Level

 

Gilson announce the release of the extended mass range VERITY® 1910 MS Detector

 

NanoFCM Opens European Office and Centre of Excellence for Scientific Application Support

 

Hitachi High-Technologies Launches Two New Scanning Electron Microscopes

 

Discovery Park & MedCity to Partner on Prestigious Angels In MedCity Programme

 

Merck Lectureship 2019 Awarded to Susumu Kitagawa

 

BioCity Invests in Carbon Recycling Start-Up, Deep Branch Biotechnology

 

Agilent Announces Unique Portfolio to Advance Immunotherapy

 

 


 

 


 

Can't find what you are looking for?

Search by company or by product


Company Name:

Product:


 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd