
Lab M is
adding to its range of Captivate
TM antibody coated paramagnetic particles for
the specific immunomagnetic separation (IMS) of micro-organisms. The
range currently encompasses products for E. coli O103, E. coli O111, E. coli
O145, E. coli O157:H7, E. coli O26, and common serotypes of Salmonella. It is
being extended to also include E. coli strains O121, O45, O91.
This
extended range will cover all ‘The Big Six' strains of non-O157 Shiga-toxin
producing E. coli (STECs) now highlighted by the United States Department of
Agriculture (USDA) as unacceptable in
raw beef products E.coli strains O26,
O103, O45, O111, O121 and O145.
Captivate
TM
accelerates the isolation of micro-organisms, primarily from food and
environmental samples. Captivate
TM particles consist of a magnetite core
enveloped by a ceramic zirconium oxide coating, to which carefully selected and
purified antibodies to surface components of the target micro-organism are
covalently coupled.
When mixed
and incubated with a sample suspension, the antibody-coated beads ‘capture' the
target bacteria by forming an antibody-antigen complex. These complexes are
separated from any background organisms or interfering materials using a
magnetic concentrator. The beads can then be plated to the appropriate
selective media or used in other analyses following a straightforward wash
procedure.
IMS
increases the sensitivity of the isolation methodology and in most
circumstances results are achieved 24 hours earlier than using standard
protocols. As well as the ready-made Captivate
TM range, Lab M provides a custom
coating service and Captivate
TM can also serve as a capture system for rapid
detection systems.
For more information visit
www.labm.com