Follow us...

 

Search News Archives

 

Special Offers and Promotions

 

 

News Channels

 

Laboratory Products

 

 

View Channel

News

 

 

View Channel

Microscopy | Image Analysis

 

 

View Channel

Separation Science

 

 

View Channel

Coronavirus (COVID-19)

 

 

View Channel

Research & Case Studies

 

 

View Channel

Brochures & Literature

 

 

View Channel

 

Conferences | Events

Sherwood Scientific’s Models 420 Flame Photometer and 926S Chloride Analyser assist with the diagnosis of Cystic Fibrosis

Cystic fibrosis is a serious genetic disorder with reduced life expectancy; common among Caucasian people, this disease occurs in one of every 3,200 Caucasian births.  

The mutation in the gene varies according to the geographical background. Cystic fibrosis occurs in one out of every 15,000 African-American births.  The life expectancy of cystic fibrosis patients has been increasing over the past 40 years.  In the 1980s life expectancy of people with cystic fibrosis was 14 years. 10 years back, it was around 18 years and today it is 35 years.  In the UK, cystic fibrosis birth is about 1 in 2400 and 4% of the people are cystic fibrosis carriers.  80% of patients are diagnosed by the age of three.  

Sherwood Scientific 926S Chloride Analyser The standard test for the confirmation of the diagnosis of the condition is the "Sweat Test" 

If sweat Chloride concentration is higher than 60 milli equivalents per litre, the result is positive.  Less than 40 and the result is negative.  The range 40 to 60 is considered borderline for adults and children. However, in case of infants, chloride concentration less than 30 is considered normal.  Those in the borderline range are expected to undergo the test a second time.   

The Model 926S Chloride analyser is ideally suited to perform this test; capable as it is of measuring samples as small as 20ul of sweat which is ideal for infant samples sizes. 

Improved diagnosis may be achieved by carefully monitoring the Sodium as well as the Chloride levels in Sherwood 420 Flame Photometerthe Sweat.  The levels of Sodium (and sometimes Potassium) may also be measured as the concentration of Sodium is lower than Chloride in the condition even if both are elevated.  This requires high levels of accuracy.  Sherwood's Model 420 Flame Photometer; with its ability to measure Sodium and Potassium simultaneously, good sensitivity and an Internal Standard Mode for optimum precision of results and stability of calibration is ideally suited to perform this analysis. 

The Sherwood Scientific Model 926S Chloride meter has been used for years for sweat Chloride determinations.  Used in conjunction with the Model 420 Flame Photometer; it is now possible to measure both Chloride and Sodium on the same sweat sample. 

For further information please click here 


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month...

Our Top 10 most popular articles this month

 

Today's Picks...

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners