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Analysis of commercial monoclonal antibodies by microLC-MS/MS

publication date: Jun 9, 2020
author/source: YMC Europe GmbH


Are you required to analyse very small sample amounts? Or do you need to analyse very low concentrations of antibodies in different kinds of matrices?

By using of microLC-MS/MS, only a very small amount of valuable samples, e.g. solutions prepared for patient application (usually a dilution of the dosage form), is required to identify and quantify. In addition, microLC-MS/MS can also be used to monitor residues on surfaces or materials in hospitals, pharmacies or laboratories that prepare solutions for patient application.

In this application note, YMC-Triart Bio C4 is used in YMC capillary column format to analyse and identify intact commercial MAbs, such as rituximab (MabThera®) or bevacizumab (Avastin®), by microLC-MS/MS.

Download the application note 'Analysis of commercial monoclonal antibodies by microLC-MS/MS' with the full method details for more information.


Download APP Note

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