Follow us...

 

Search News Archives

News Channels

 

Coronavirus (COVID-19)

 

 

View Channel

New Laboratory Products

 

View Channel

Lab News

 

View Channel

Research & Case Studies

 

View Channel

Microscopy | Image Analysis

 

View Channel

Separation Science

 

View Channel

Videos

 

View Channel

Events | Webinars

 

View Channel

Conferences | Events

MIMETAS and Hubrecht Organoid Technologies to Develop and Market Organoids-on-a-Chip

publication date: Oct 15, 2019
 | 
author/source: MIMETAS
mimetas-and-hubrecht-organoid-technologies-develop-and
Human colon organoid in MIMETAS OrganoPlates. Organoids are grown from adult stemcells derived from donor tissue. The organoids are grown as a tube in the MIMETAS OrganoPlate, allowing access to both the basal and apical side of the mini-gut. The MIMETAS platform does not comprise any artificial membranes and allows for excellent imaging.

 

MIMETAS and Hubrecht Organoid Technologies (HUB) announce that they entered into a strategic collaboration to market organoid models on a Chip.

The agreement includes a license to MIMETAS to market HUB Organoids in an assay ready format, as well as a collaborative effort to develop disease-specific models.

"We're delighted and proud that we could transition our long-standing collaboration with the group of Professor Hans Clevers into a commercial proposition," says MIMETAS CEO Paul Vulto. "The adult stem cell biology and Organoid technology of HUB is the very best in the world. By combining it with our OrganoPlate technology in an assay-ready format, the technology becomes available to researchers from any laboratory in the world.”

“We are excited to work with MIMETAS and add a range of new assay systems to the HUB Organoid platform,” says Dr. Rob Vries, CEO at HUB. “The OrganoPlate platform is unrivaled in its field. It is a perfect fit with our biology and enhances ease of use, imageability, and screenability of complex Organoid models. Together we will develop diseased and healthy patient-relevant models that serve the needs of the drug development industry.”

 

more about mimetas


 

About MIMETAS

MIMETAS (Leiden, the Netherlands, Gaithersburg, USA, Tokyo, Japan) provides organ-on-a-chip products for compound testing, screening, and fundamental research. Its flagship product, the OrganoPlate®, supports 3D cell culture under continuous perfusion, with membrane-free co-culture and epithelial and endothelial tubules. The company develops and validates customized disease, toxicology, and transport models and ultimately will make its technology available for personalized therapy selection. MIMETAS has developed models for the kidney, liver, gut, brain, and a range of oncological applications, that offer better predictivity towards human physiology as compared to laboratory animals and conventional cell culture models. MIMETAS works with the majority of the global top-50 pharmaceutical companies, in addition to chemical, food, and consumer goods companies. The fast market acceptance of the OrganoPlate® is driven by its unsurpassed ease-of-use and throughput, in combination with complex human biology and disease relevance.

 

About HUB

HUB is founded on the pioneering work of Prof. Hans Clevers, who discovered methods to grow stem cell-derived human ‘mini-organs’ (HUB Organoids). The proprietary HUB Organoid Technology enables the generation of in-vitro models of any epithelial disease from any patient. HUB Organoids mimic organ functionality and are considered to be a clinically relevant model for human diseases such as Cystic Fibrosis, oncology and toxicology.

HUB Organoids or a “Patient in the Lab”, allow for better understanding of tumor heterogeneity and drug response. HUB has established a “Living Biobank” that links patient-specific genetic and phenotypic information to pre-clinical drug discovery, compounds validation and clinical drug-response. In drug development, HUB organoids can efficiently identify novel therapeutic targets, provide drug efficacy, safety and mechanistical data.

In addition to drug screening services, HUB offers licenses to its patented HUB Organoid Technology for drug-screening and access to Organoids in the HUB biobanks for pre-clinical drug discovery and validation. In addition, HUB is performing clinical studies to validate the technologies used as a companion diagnostic.




 

 

Popular this Month...

Our Top 10 most popular articles this month

 

Today's Picks...

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd

 

 

 

Media Partners