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All articles from SP Scientific Inc.

  NEW Brochure from SP Service

Engineering Experience and Expertise to Help You Protect Investments and Maximize Equipment Productivity. SP Service offers an exceptional depth of expertise to help keep equipment performing at its very best. We are recognized experts in applications, methodologies, laboratory and manufacturing processes, and many other areas that directly impact your facility's day-to-day operation...

 

  SP

Cutting-edge SP i-Dositecno robotic filling and capping equipment to be installed in NIBRT’s global center of excellence for bioprocessing training and research. SP Scientific Products (SP) announces a collaboration with the National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland, to install a modular multi-container filling line and isolation system...

 

  SP expands freeze dryer loader range for advanced aseptic pharmaceutical processing

SP Scientific Products (SP) announces that it has expanded its freeze dryer loader range with the launch of two new fully GMP compliant loading systems compatible with SP Hull LyoConstellationTM freeze dryers. Designed for advanced aseptic pharmaceutical processes involving lyophilization, SP’s latest loader introductions offer flexible and innovative solutions for small to medium batch and high-speed full line aseptic vial handling applications....

 

  US Congressman commends the contribution of SP Industries in the fight against COVID-19

SP Industries, Inc. (SP), has hosted a visit by US Congressman, Brian Fitzpatrick, who was on a fact-finding mission to find out more about the work SP is doing to support Operation Warp Speed, and discuss SP’s plans for increasing capacity and capabilities. Operation Warp Speed (OWS), an initiative of the US Department of Health & Human Services (HHS), aims to...

 

  SP Scientific launches the HT Series 3i Evaporators

SP Scientific has announced the launch of the HT Series 3i Evaporators, the updated replacements for the highly successful HT Series 3 evaporator range. Already established as the ultimate in solvent removal technology, the new HT Series 3i evaporators have been developed to be even more user- and environment-friendly, while enabling enhanced evaporation and lyophilization results.

 

  AstraZeneca Invest In Small Scale GMP Production of Parenterals

SP Scientific report that AstraZeneca BioPharmaceuticals R&D (Gothenburg, Sweden) has invested in a LyoConstellation™ S10 freeze dryer intended to help drive research and development of small scale GMP production. The SP Scientific LyoConstellation system is planned for use on multiple projects to support early to late phase development including GMP production of small batches for Phase 1 and Phase 2 clinical trials....

 

  Delivering Complete Aseptic Vial Handling Solutions

SP Scientific announces the signing of a new partnership agreement with Lab-i-DOSiTECNO Pharma Technologies (Barcelona, Spain) enabling both companies to offer complete aseptic vial and syringe fill-finish lines lines for Injectable, Ophthalmic & Oral Products in Liquid and Powder Form. This new global partnership brings together best in class freeze drying and vial washing/sterilizing technologies....

 

  Controlled Rate Freezing of Biological Samples

BioCoolSP Scientific introduces the new BioCool V40 - a robust and reliable mechanically refrigerated 1.5-litre system designed for controlled rate freezing of biological materials including blood, embryos and tissue samples. The BioCool V40 is the only controlled rate freezer that does not require expendable liquid nitrogen and the associated pumping, re-filling, and storage challenges posed by a cryogenic liquid....

 

  Extensive Natural Product Fraction Library for High-Throughput Screening

Genevac Series 3 HT-12 Centrifugal EvaporatorSP Scientific’s Genevac Series 3 HT-12 Centrifugal Evaporator has been cited in a recently published paper by theNatural Products Support Group, Leidos Biomedical Research,Inc.and theFrederick National Laboratory for Cancer Researchas an important sample preparation tool in their extraction and pre-fractionation work to create a new natural product fractions library.

 

  Freeze-Drying Microscope Generates Critical Formulation Specific Data

SP Scientific has video interviewed Dr Kevin Ward of Biopharma Process Systems Ltd, to discuss the key benefits of the Lyostat5 Freeze-Drying Microscope (FDM), and how it can be used to generate critical formulation-specific data. Every freeze-drying formulation has a critical temperature, below which it should be maintained during primary drying in order to prevent processing defects....

 

  Automated Evaporative Sample Preparation for Clinical Biochemistry

SP Scientific’s Genevac EZ-2 Centrifugal Evaporator is providing the Clinical Biochemistry department at a leading UK hospital with a reliable, easy-to-use method of preparing clinical samples ready for testing. Clinical laboratories play a vital role in the healthcare industry as about 80% of the clinician’s diagnoses are based on laboratory analysis with a range of tests carried out on clinical specimens, to obtain information about....

 

  Effective Removal of DMSO from Stored Samples

Series 3 HT evaporatorSP Scientific’s Genevac Series 3 HT Centrifugal Evaporator is widely proven to provide highly effective drying of samples previously stored in Dimethyl Sulphoxide (DMSO). Dimethyl sulfoxide (DMSO) is an important polar aprotic solvent that dissolves both polar and non-polar compounds and is miscible in a broad range of organic solvents as well as water. Because of these properties it is widely used as a universal sample storage solvent. However...

 

  How to Avoid Residual Solvent When Drying HPLC Fractions

Driven by the requirement for completely dry samples, pharmaceutical compound handling groups are increasingly using SP Scientific’s Genevac LyoSpeed™,a hybrid process combining conventional centrifugal evaporation and lyophilization, as their preferred method for drying HPLC reverse-phase solvent fractions. Using LyoSpeed™ technology on Genevac EZ-2 Elite and Series 3 HT evaporators, HPLC fractions can be automatically concentrated to a few milliliters, then frozen and rapidly lyophilized....

 

  New Powerful Freeze Dryer Offers Fully Aseptic Operation

SP Scientific announces the LyoConstellation S10, S20 and S30 as the first in a new series of advanced freeze dryers.  All are configured-to-order for faster delivery freeze-drying cycle development and small-scale aseptic production, such as production of stability batches or early phase clinical trial batches. LyoConstellation is a Line of Sight™- enabled freeze-drying system with very powerful refrigeration, delivering an...

 

  SP Scientific Launches New Microsite Highlighting its Line of Sight Approach

SP scientificSP Scientific has launched a microsite dedicated to its new Line of Sight (TM) approach, a breakthrough suite of freeze-drying equipment with scalable lyophilization and process analytical tools (PAT). The goal of Line of Sight is to bring pharmaceutical products safely and quickly to market by enhancing product and process knowledge at every step and substantiate the process within...

 

  New Powerful Control System for Development to Production Scale Lyophilization

LyoS™ 2.0SP Scientific announces the launch of LyoS™ 2.0 – a line-of-sight enabled lyophilizer control system able to control platforms from development to production units, making cycle transfer and scale-up that much simpler. Building upon over 50 years of freeze-drying experience, the LyoS 2.0 control system delivers unmatched process control for all stages of the cycle, from freezing to primary and secondary drying...

 

  European Freeze-Drying Seminar

GILYOSSP Scientific announces sponsorship of the popular 14th annual European freeze-drying seminar Lyoscopedia, being held in the Congress Centrum (Würzburg, Germany) on March 13, 2019. Designed for both freeze-drying experts and novices, the interactive seminar format of Lyoscopedia 2019 provides a platform for exciting discussions about freeze-drying topics relevant to both academic research and...

 

  Freeze-Drying Technologies Enhance Process Development with Small Amounts of API

Join SP Scientific and Dr. Alexandra Braun, of GILYOS GmbH, for an insightful webinar on miniaturization in freeze drying. Miniaturization is an important topic – especially in the early development phase of new drug entities – due to the limited availability and costs of most Active Pharmaceutical Ingredients (API). This webinar, which takes place on January 24 2019, will focus on ways to jumpstart your development effort...

 

  Precision Temperature Control for NMR, EPR & XRD Studies

XRThe AirJet XR Sample Cooler from SP Scientific is designed to provide precision sample temperature control (-90°C to +100°C) for NMR, EPR and X-Ray Diffraction instruments using a mechanically refrigerated, temperature-controlled air stream. Unlike some systems that use expensive, expendable cryogens such as liquid nitrogen or carbon dioxide to control temperature, the AirJet XR requires only house-compressed air to control temperature....

 

  Convenient Benchtop Tray Freeze Dryer

AdVantage Pro freeze dryerThe AdVantage Pro freeze dryer with advanced controller from SP Scientific now offers users the benefit of ethernet communication to allow you to monitor your cycle from anywhere that you can receive email. Designed for pharmaceutical and biotech labs, the AdVantage Pro has comparable shelf temperature uniformity (+/- 1.0°C) and system vacuum control performance to larger production freeze dryers, but in a convenient benchtop package. At only 26 in (66 cm) wide, the Advantage Pro requires a minimal amount of your valuable bench space...

 

  Custom OEM Glass Parts Manufacturing

Utilizing Precision Bore TubingWilmad-LabGlass, an SP Scienceware company, is a leading supplier of precision OEM glass and quartz parts for applications including flow cytometry, distillation, dissolution, rheology, clinical diagnostics and process flow measurement and their relevant equipment. Drawing upon over 76-years’ experience of innovative design and manufacturing to the highest tolerances with the strictest quality control – Wilmad-LabGlass has become the preferred glass products...

 

  Extremely Versatile Freeze Dryer

benchtop proSP Scientific announces that its popular Benchtop Pro freeze dryers now include an Omnitronics™  controller as standard enabling application specific programming. The Omnitronics™ controller is driven by an industrial-grade programmable logic controller (PLC), which provides extreme versatility while remaining intuitively easy to use....

 

  Insights in Lyophilization Science Tour

Lyophilization Science TourSP Scientific, a leading innovator in freeze drying and lyophilization equipment, has announced the dates, venues and agendas for its September 2018 international ‘Insights in Lyophilization Science’ tour. With informative seminar programs published for Basel (Switzerland), Dublin (Ireland), Boston (USA) and Warminster (USA), attending the tour is a must for anyone involved or interested in lyophilization science...

 

  Versatile Lyophilizer for Research, Development or Small-Scale Production

Vir TisThe Genesis Lyophilizer from SP Scientific has been designed with versatility in mind so that this freeze dryer can meet virtually any research, development or small-scale production lyophilization application. The Genesis is highly configurable and designed to deliver shelf temperatures as low as -70°C, condenser temperatures to -85°C, operate in bulk or stoppering configurations....

 

  Evaporative Sample Preparation Protocol Improves Natural Product Extraction

Genevac has published a technical article that describes how its Rocket™ Evaporator has been used by the Technical University of Munich (Germany) as a sample preparation tool for extraction of active phytochemicals from the leaves of Gymnema sylvestre. A Genevac Rocket Evaporator was chosen to dry the samples because of its high-volume sample capacity, unique technology that eliminates cross contamination due...

 

  SP Industries Announces Brian M. Larkin New President and CEO

SP Industries Inc. has announced the appointment of Brian Larkin as its President and Chief Executive Officer effective February 19th replacing William (Bill) Downs who recently retired. Mr. Larkin brings to SP broad experience as a senior executive having spent the last 27 years in commercial and executive leadership roles in the medical device industry. Most recently he served as Vice President and General Manager for Becton Dickinson's...

 

  Informative Spring 2018 Freeze Drying Webinars Program

spscientific laptopThe new Spring 2018 program of LyoLearn™ educational webinars has been announced by SP Scientific. Devoted to lyophilization current research interest and related topics, and delivered by industry experts, attendees to each of the free live sessions are encouraged to ask questions of the presenter and get their answers in real time. On 21st February 2018, Dr Michael Pikal, recently retired...

 

  Flexible Freeze Dryer for High Quality Preparation of Peptides and Proteins

Freezemobile freeze dryerThe Freezemobile freeze dryer from SP Scientific is designed to provide a convenient and flexible solution for high quality preparation of peptides, proteins, plant materials and organic tissue. Unlike many traditional freeze dryers that employ coil condensers, Freezemobile freeze dryers use a smooth walled condenser which enables fast defrost & removal of ice for faster turn-around time and also...

 

  Desktop Centrifugal Concentrator for Nucleic Acids

The miVac DNA centrifugal sample concentrator from Genevac is purpose designed to efficiently remove water and organic solvents from biological samples containing nucleic acids. The compact benchtop system includes a built-in high-performance vacuum pump, concentration chamber with electromagnetic drive for quiet, maintenance-free operation, and a fixed aluminium rotor for microcentrifuge tubes. To use your miVac DNA – simply position the system on your lab bench, connect the power lead and exhaust tube and then start benefiting from fast, trouble-free nucleic acid concentration....

 

  Efficient Concentration of Nucleic Acids

miVacThe miVac DNA centrifugal sample concentrator from Genevac is purpose designed to efficiently remove water and organic solvents from biological samples containing nucleic acids. The compact benchtop system includes a built-in high-performance vacuum pump, concentration chamber with electromagnetic drive for quiet, maintenance-free operation, and a fixed aluminium rotor for microcentrifuge tubes....

 

  Study Demonstrates Outstanding Results from Mini Freeze Dryer

SP Scientific announces publication of an independent study evaluating their LyoCapsule™ Freeze Dryer for pharmaceutical product formulation and process development.

LyoCapsuleThe development of biopharmaceuticals often requires lyophilized formulations to produce stable drug products, beginning with laboratory experiments followed by scale-up to larger lyophilizers. Limited supply and high cost of Active Pharmaceutical Ingredient (API) can present major challenges during formulation and process development....

 

  Expanding Applications for Temperature/Humidity Controlled Stability Chambers

SP Scientific reports upon the growing range of applications served by its premium Hotpack Stability Chambers.

Hotpack Stability ChambersAvailable in a variety of customizable models, these systems provide precision temperature control from 2°C to 70°C and 20% to 96%RH with exceptional uniformity throughout the chamber and therefore can serve a diverse array of applications across a multitude of industries....

 

  Temperature/Humidity Controlled Stability Chambers

SP Scientific reports upon the growing range of applications served by its premium Hotpack Stability Chambers.

Hotpack Stability ChambersAvailable in a variety of customizable models, these systems provide precision temperature control from 2°C to 70°C and 20% to 96%RH with exceptional uniformity throughout the chamber and therefore can serve a diverse array of applications across a multitude of industries....

 

  Productive Space Saving Laboratory Evaporator

Genevac reports that its Rocket Synergy centrifugal evaporator is being adopted by laboratories looking to replace multiple rotary evaporators, from benchtop to production capacity, saving them valuable bench space and improving productivity.

Rocket Synergy evaporator Rocket Synergy evaporator controls are very easy to use - simply load your samples, select the correct method, press start and walk away. The evaporator is equipped with high performance features that prevent foaming, bumping and cross contamination. A built-in cold trap provides very high levels of solvent recovery, even with volatile organic solvents....

 

  Accelerate Your Freeze Drying Cycle Development with Just 7 Vials

SP Scientific announces the LyoCapsule™ Freeze Dryer.

LyoCapsule™ Freeze DryerAn exciting new lyophilization instrument that delivers results comparable to larger R&D freeze dryers enabling a Quality by Design (QbD) approach to cycle development even when materials are highly expensive or limited in quantity. This addition aligns with SP’s mission to provide ‘line of sight’ scale-up equipment and technology from R&D through to commercial freeze drying....

 

  SP Scientific Launches New PennTech Website

SP Scientific announces the launch of a new dedicated website for its PennTech® brand of advanced aseptic processing equipment for the pharmaceutical and biotech industries.

SP Scientific’s PennTecAs the only U.S.-based manufacturer to offer complete vial handling solutions covering washing, sterilization, filling, stoppering, capping and both tray and freeze dryer loading/unloading equipment – SP Scientific’s PennTech® brand has earned an international reputation for supplying reliable, high performance equipment....

 

  Ensuring Robust Lyophilization Scale-Up

SP Scientific announces the on-demand availability of a popular webinar by Jake Luoma of Genentech Inc. that discusses how controlled nucleation has emerged as a technology which promises improvements in lyophilization process throughput and consistency. 

Lyophilization Scale-UpIn this presentation, Mr. Luoma examines the benefits of the technology for high fill-volume configurations and presents new data regarding the mechanism of the ControLyo™  Technology.  The presentation shows how gaining a more complete understanding of the mechanism of nucleation using ControLyo™ Technology ensures more robust freezing when scaling from the lab to commercial-scale freeze dryers....

 

  "Arctic Blast" Yields Better Lyophilisation Results

Benefiting from a state-of-the-art -75°C condenser - the Series 3 HT Evaporator from Genevac sets a new benchmark for enhanced evaporation and lyophilisation results.

Drying HPLC purification fractionsDrying HPLC purification fractions, such as water and acetonitrile, is a routine yet essential task in many pharmaceutical laboratories.  Typically labs require HPLC fractions to be dried to a powder form, such that samples can be accurately weighed, easily sub-sampled and re-dissolved....

 

  Reducing Risk of Contamination on the Outside of Vials

SP Scientific has published a white paper that discusses how the pharmaceutical industry and safety regulators are putting more emphasis on the importance of using external washers to remove particles from the outside of vials. 

freeze dryers / lyophilizersMany organizations today are electing to install external vial washers in association with filling applications involving powders, high potency liquids and freeze-dried materials to minimize the risk of operator or end-user exposure to harmful products. The white paper provides an informative introduction to...

 

  New Evaporative Technique Improves Environmental Sample Preparation

Genevac reports on a customer paper that describes the development and advantages of a new evaporative methodology for Mass Spectroscopic (MS) analysis replacing the traditional Solid Phase Extraction (SPE) technique for preparing environmental samples.

EZ-2In recent years HPLC/MS/MS and UPLC have become the sensitive and specific techniques of choice for the detection of algal toxins in water. While the majority of published studies employ SPE for preparing environmental samples for MS or UPLC analysis, using this methodology can be very time consuming. In this paper a direct solvent evaporation methodology...

 

  SP Scientific Purchases ControLyo Nucleation Technology

SP Scientific has purchased ControLyo™ Nucleation Technology and all related patents from Praxair Inc. (Danbury, CT).

optimization of freeze-drying cyclesControLyo™ nucleation technology controls the freezing stage of the freeze drying process for more consistent and repeatable outcomes that aid drug development, scale-up and production efforts. SP which manufactures a full range of research through production lyophilization equipment and technologies has had a licensing agreement with Praxair, Inc. to provide ControLyo™ technology as part of its portfolio since 2010...

 

  SP Announce 2017 Hands-On Freeze Drying Course Schedule

SP Scientific, the market leader in freeze drying educational events, reports on the enthusiastic response from past attendees at its 'Hands-On' training courses and announces dates for its 2017 program.

2017 Hands-On Freeze Drying Course ScheduleOver the last 6 years, SP Scientific Hands-On freeze drying training courses have proven invaluable to attendees. Tangible benefits that attendees have immediately realised on returning to work include increased productivity through cutting hours from their freeze drying cycle recipes and troubleshooting real issues faced in their daily work environments....

 

  SP Scientific Expands Pharmaceutical Processing Equipment Range

SP Scientific is now able to offer a one-source solution for a complete range of pharmaceutical processing equipment. 

 freeze dryers / lyophilizersFrom lyophilizers / freeze dryers, vial washers and sterilization tunnels right through to automated systems for filling, loading / unloading, capping and external washing of vials, PennTech, Hull and VirTis brands advantageously position SP Scientific with capability to manufacture complete aseptic vial processing lines....

 

  Powerful Software Utility for Modelling Freeze Drying Cycles

SP Scientific announces the introduction of the LyoModelling Calculator (LMC) - a powerful new software utility that enables those developing freeze drying cycles to calculate the time required for primary drying and the maximum product temperature based on user data input. 

 LyoModelling CalculatoThis free software resource is available on the SP Scientific website**. Users obtain a starting point for primary drying duration and the maximum product temperature at the sublimation interface using pertinent information, such as shelf temperature and chamber pressure, from which an optimized freeze-drying cycle can be developed. The LMC is based on the steady-state heat and mass transfer model of primary drying developed by...

 

  SP Scientific Video Details Expanded Capabilities in Pharmaceutical Processing Equipment

SP Scientific is now able to offer a one-source solution for a complete range of pharmaceutical processing equipment. 

spscientificFrom lyophilizers / freeze dryers, vial washers and sterilization tunnels right through to automated systems for filling, loading / unloading, capping and external washing of vials, PennTech, Hull and VirTis brands uniquely position SP Scientific as the only company in the United States with capability to manufacture complete aseptic vial processing lines....

 

  Comparison of Methods for Concentrating Winterised Cannabis Extract

Genevac has posted a YouTube™ video of a demo at California Gold Extractions (San Diego, USA) which compares use of a rotary evaporator and the Genevac Rocket Synergy evaporator, for the batch concentration of 2 litres of winterised cannabis extract in ethanol.

Genevac Rocket and Rocket 4D Synergy evaporatorsCannabis oil extract has been used medicinally for generations to help treat a variety of conditions, and its popularity has increased considerably in recent years. Of the various extraction methods used, ethanol extraction is increasingly becoming the method of choice because of its ability to economically and effectively produce an extract with a high terpene content that is safe for consumption...

 

  SP Acquires PennTech Machinery Corporation

SP Industries, Inc. (SP), a leading designer and manufacturer of state-of-the-art laboratory equipment ; research, pilot and production freeze dryers ; laboratory supplies and glassware has announced that it has acquired the assets of privately held PennTech Machinery Corporation.

SP ScientificPenntech is a global provider of complete vial handling solutions covering washing, sterilization, filling, stoppering, capping and both tray and freeze dryer loading/unloading equipment, located in Warminster (PA, USA). “PennTech has a well-earned reputation for producing high quality, often customized, equipment and is the only U.S. based manufacturer to offer complete aseptic processing lines,” stated...

 

  Rapid, High-Throughput Alternative to Freeze Drying HPLC Fractions

Fast Lyophilisation on the Genevac Series 3 HT Evaporator was developed to provide a rapid, high-throughput alternative to freeze drying HPLC purification fractions.

Freeze Drying HPLC FractionsTraditional evaporation methods of removing solvents, such as water and acetonitrile, often results in formation of a gum or oil due to solvent interactions with the dissolved sample. Employing a Series 3 HT Evaporator with LyoSpeed™ Fast Lyophilisation technology is enabling pharma labs to now routinely dry HPLC fraction samples to a powder form, such that the samples can then be accurately weighed, easily sub-sampled and redissolved. While standard evaporation works...

 

  Fast Lyophilisation of HPLC Fractions

Fast Lyophilisation on the Genevac Series 3 HT Evaporator was developed to provide a rapid, high-throughput alternative to freeze drying HPLC purification fractions.

Genevac Series 3 HT EvaporatorTraditional evaporation methods of removing solvents, such as water and acetonitrile, often results in formation of a gum or oil due to solvent interactions with the dissolved sample. Employing a Series 3 HT Evaporator with LyoSpeed™ Fast Lyophilisation technology is enabling pharma labs to now routinely dry HPLC fraction samples to a powder form, such that the samples can then be accurately weighed, easily sub-sampled and redissolved. While standard evaporation works...

 

  Flexible Solution for High Throughput Evaporation

Genevac Series 3 HT evaporators provide an ideal solution for evaporation bottlenecks in high throughput medicinal chemistry, natural product and production laboratories that generate large numbers of samples for processing.

Genevac Series 3 HT evaporatorsCompact in design and offering a very high capacity for a wide range of sample formats including microplates, vials, and fraction collection tubes, Series 3 HT evaporators offer the versatility and productivity to assist chemists tasked with drying large numbers of samples. The high-throughput design of a Series 3 HT evaporator allows up to 48 shallow-well microplates to be dried down at the same time, while capacity for standard 16 x 100mm fraction collector tubes is...

 

  Informative Program of Lyophilization Events

SP Scientific has announced their next series of educational events to be held during 2016 for scientists involved with lyophilization.

SP scientificInformation and registration details for these upcoming events which include LyoLearn webinars, seminars and hands-on training courses is available through the SP LyoTech Center**. In addition to upcoming events, the LyoTech Center offers a comprehensive repository of previously recorded webinars; informative articles and technical papers; and a variety of free tools and programs to assist freeze dryer users. LyoLearn webinars...

 

  SP Scientific Announces 2016 Freeze Drying Education Program

SP Scientific has announced their next series of educational events to be held during 2016 for scientists involved with lyophilization.

 Freeze Drying Education ProgramInformation and registration details for these upcoming events which include LyoLearn webinars, seminars and hands-on training courses is available through the SP LyoTech Center**. In addition to upcoming events, the LyoTech Center offers a comprehensive repository of previously recorded webinars; informative articles and technical papers; and a variety of free tools and programs to assist freeze dryer users. LyoLearn webinars...

 

  SP Scientific Introduce New Range of Hotpack Glassware Washers

SP Scientific has introduced a new range of Hotpack Undercounter and Doublestack Glassware Washers that are engineered for productive, reliable and energy efficient operation. 

Hotpack Undercounter and Doublestack Glassware WasherTechnological developments allow the new washers to deliver enhanced drying performance from an upgraded dual fan system incorporated in the washer chambers. Wash cycles with temperatures up to 70°C (158°F) enable fast, efficient cleaning of different types of glassware in wide ranging load scenarios. New soft touch features with multiple cycle selections and microprocessor control systems ensure that each load is processed with minimum energy consumption. A delayed start...

 

  Productive Ultra Quiet Glassware Washers

SP Scientific has introduced a new range of Hotpack Undercounter and Doublestack Glassware Washers that are engineered for productive, reliable and energy efficient operation. 

Doublestack Glassware WashersTechnological developments allow the new washers to deliver enhanced drying performance from an upgraded dual fan system incorporated in the washer chambers. Wash cycles with temperatures up to 70°C (158°F) enable fast, efficient cleaning of different types of glassware in wide ranging load scenarios. New soft touch features with multiple cycle selections and microprocessor control systems ensure that each load is processed with minimum energy consumption. A delayed start...

 

  Versatile Accessory for Bulk and Flask Freeze Drying

SP Scientific has announced the Horizontal Drum Manifold - a new accessory to maximize the performance of its BenchTop Pro freeze dryer while adding bulk and flask drying capabilities for aqueous application.

 Horizontal Drum ManifoldDesigned for use with 3-, 8- and 9-Liter BenchTop Pro units the new manifold provides a highly economic solution to further increase the versatility of the popular tray dryer either purchased with a new system or easily assembled on an existing unit in the field with no additional hardware required. The Horizontal Drum Manifold comes standard with two adjustable unheated trays that provide ample room for bulk samples such as plants, leaf...

 

  Effective Surface Sterilization of Freeze Drying Equipment

SP Scientific has partnered with Bioquell (Andover, UK) to produce an off-the-shelf surface sterilization/decontamination system for SP freeze dryers.

Bioquell L-3The freeze drying production of many pharmaceuticals and biological materials requires sterile conditions. Traditionally freeze dryers have used steam for sterilization. Unfortunately, working with steam means that the freeze dryers are exposed to many different stresses and strains. SP Scientific, in conjunction with Bioquell, have developed an equally effective and less expensive solution to perform surface sterilization / decontamination of freeze dryers using hydrogen peroxide vapor (HPV)...

 

  Effective Surface Sterilization / Decontamination of Freeze Drying Equipment

SP Scientific has partnered with Bioquell (Andover, UK) to produce an off-the-shelf surface sterilization/decontamination system for SP freeze dryers.

spscientificpr66The freeze drying production of many pharmaceuticals and biological materials requires sterile conditions. Traditionally freeze dryers have used steam for sterilization. Unfortunately working with steam means that the freeze dryers are exposed to many different stresses and strains. SP Scientific, in conjunction with Bioquell, have developed an equally effective and less expensive solution to perform surface sterilization / decontamination of freeze dryers using hydrogen peroxide vapor...

 

  Evaporative Sample Preparation for Metabolism and Toxicology Studies

Genevac has launched a web page that brings together the latest technological innovations and application advances, with links to reference papers, detailing how new fast, safe evaporative sample preparation techniques are benefiting metabolism and toxicology studies.

genevac evaporatorsVisitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...

 

 

  Sub-Visible Particles: Impact On Therapeutic Proteins

SP Scientific has announced a new LyoLearn webinar, due to run on 27th June 2013, entitled 'Sub-visible Particles: Impacts on Aggregation Pathways, Adverse Immunogenicity and Regulatory Expectations for Therapeutic Proteins'.

Dr John CarpenterDuring the session, Dr. John Carpenter Professor of Pharmaceutical Sciences and Co-Director of the Center for Pharmaceutical Biotechnology, University of Colorado (USA), discusses key areas and presents the latest results from his research. In addition, he will highlight the particle counting instruments that have been vital to the progress made to date. Over the past several years there has been greatly increasing attention on sub-visible particles in therapeutic protein products...

 

  SP Scientific Unveils New Benchtop Freeze Dryer

The new VirTis BenchTop Pro freeze dryer range from SP Scientific have been designed to be highly affordable, yet meet the needs of the most demanding research laboratories. Each system can be configured to meet your present and future needs.

VirTis BenchTop Pro freeze dryeCondenser refrigeration packages of -55°C, -75°C, -85°C and -105°C allow you to meet the demands of both aqueous or aqueous solvent based formulations. You can configure your system for smaller sample numbers or to process a relatively heavy workload with condenser size choices of 3 liter, 8 liter or 9 liter. This built-in flexibility allows you to maximize the use of the freeze dryer in your lab while not paying needlessly for unnecessary capacity or refrigeration....

 

  Optimizing Freeze Dried Drug Dosage Form to Treat Muscle Atrophy

Using a SP Scientific LyoStar Freeze Drying System, leading pharmaceutical process development experts - GILYOS GmbH (Wuerzburg, Germany) will participate in a research program called "FORMOsA" which was recently funded with about two million euros by the German Bavarian Research Foundation. The project focuses on age-related muscle atrophy (sarcopenia)

Lyostar Freeze Drying system In this project, GILYOS will be actively involved in the formulation development and freeze drying process design and optimization of follistatin for subcutaneous application. Follistatin is a messenger substance which is present in almost all types of tissue. The protein effectively inhibits myostatin which, in turn, plays a key role in skeletal muscle atrophy. Follistatin might therefore be a promising substance for treating sarcopenia...

 

  SP Scientific Announces Fall 2012 Lyophilisation Webinars

SP Scientific has announced its fall 2012 program of free educational webinars delivered by industry experts on topics in Lyophilisation and Freeze Drying

sp scientificPresented by Yves Mayeresse, Director of Manufacturing at GlaxoSmithKline Biologicals - the 23rd August webinar examines and discusses 'Challenges and Opportunities When Scaling Up Your Lyophilized Pharmaceutical Products'. The presentation provides an overview of factors influencing the success of scale-up. The equipment difference, the robustness of the formulation and the required adaptation of the freeze-dried sample will be reviewed in the presentation...

 

  SMART Technology Accelerates Determination of Freeze Drying Product Resistance SP Scientific has written a new technical article that describes research undertaken to understand the impact of controlled nucleation temperature on freeze drying product resistance.

SMART™ Freeze Dryer technology The researchers demonstrate how SMARTTM Freeze Dryer technology is able to simplify and accelerate the determination of product resistance during controlled nucleation freeze drying experiments. SMART Freeze Dryer technology is a unique control software tool proven to enable development scientists to accelerate and streamline the arduous task of developing and optimizing freeze drying cycles...

 

  SP Scientific and Praxair Expand Technology Agreement SP Scientific, and Praxair Inc., headquartered in Danbury, CT, are pleased to announce the expansion of their collaborative relationship to commercialize Praxair's ControLyoTM Nucleation on Demand Technology.

SP ScientificThe original agreement, signed in October 2010, gave SP Scientific the exclusive, global rights to commercialize the technology on Development Lyophilizers <1.0 m. The Praxair ControLyoTM Technology was implemented on SP Scientific's Lyostar 3 Freeze Dryer in December 2010. The expansion of the agreement allows SP Scientific to also equip its clinical, pilot and production dryers (Benchmark series and Hull Production Dryers) with the ControLyoTM Technology...

 

  Freeze Drying of Pharmaceuticals & Biologicals Freeze Drying of Pharmaceuticals & Biologicals SP Scientific has announced new dates for its popular educational seminars and hands-on laboratory training courses in freeze drying techniques. A new seminar 'Freeze Drying of Pharmaceuticals & Biologicals' has been developed in conjunction with Dr. Henning Gieseler and the University of Erlangen Freeze Drying Focus Group - one of the premier academic groups in the world focused on lyophilization...

 

  Lyophilization Cycle Development & Optimization training courses in freeze drying techniquesSP Scientific has announced, in response to widespread enthusiastic participant response to its previous hands-on laboratory training courses in freeze drying techniques, new dates for a Fall 2011 programme...

 

  Improving Accelerated Solvent Extraction (ASE) Workflow Genevac has launched the Flip-Flop™ systemGenevac has launched the Flip-FlopTM system to improve post Accelerated Solvent Extraction (ASE®) concentration and preparation of samples. Using the special double-ended Flip-FlopTM tube - samples can be collected directly from a Dionex ASE® system. A SampleGenieTM adaptor with GC vial is then fitted. The tube is flipped over and placed into the Puck sample holder in a Genevac Rocket Evaporator and the cap removed. The samples are then concentrated directly into a GC autosampler vial...

 

  Fast and Efficient Benchtop Freeze Drying The Benchtop™ K Series of Manifold Freeze Dryers from SP Scientific The BenchtopTM K Series of Manifold Freeze Dryers from SP Scientific are designed for laboratories looking for compactness and ease of use without compromising performance. The Benchtop K Series brings fast and efficient freeze drying within the budget of almost any laboratory. Ease of use is ensured by one button start-up that activates all operating parameters in the correct sequence. All Benchtop K Series Freeze Dryers employ environmentally friendly CFC-free refrigeration systems...

 

 

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