Axis Healthcare, a family-run care facility in Oklahoma, has introduced VOYAGER adjustable tip spacing pipettes from INTEGRA Biosciences into its PCR laboratory workflows. These multichannel pipettes offer the laboratory a straightforward and easy-to-use liquid handling solution to provide accurate and high throughput testing as part of a holistic strategy to support patients in overcoming opioid addiction...
A team of scientists, from the University of Bath’s Department of Chemistry and Institute for Sustainability have found a way to create two of the world’s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry. It is perhaps not widely known that many common pharmaceuticals are manufactured using chemical precursors derived from crude oil, presenting a niche sustainability challenge as the world targets Net Zero...
A new six-month science expedition in low Earth orbit (LEO) begins when four astronauts launch to the International Space Station (ISS) as part of NASA’s SpaceX Crew-7 mission. While onboard the space station, the Crew-7 astronauts, who will be part of Expeditions 69 and 70, will perform a variety of investigations sponsored by the ISS National Laboratory. This 7th rotational crewed mission from SpaceX, which is part of NASA’s Commercial Crew Program, is scheduled to launch from NASA’s Kennedy Space Center in Florida...
Promega scientists contribute to new research to improve precision and efficiency of groundbreaking gene editing technique. A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing. The results demonstrate how this groundbreaking technique can be enhanced by using two inhibitors to boost insertion rates and reduce off-target effects...
Growing demand for analytical laboratory services (and the impact of the COVID-19 pandemic) will see the industry grow globally to about $492 million by 2027. Batch Release Testing shows the biggest growth in the market, estimated to increase at 9% Compound Annual Growth Rate (CAGR). To keep up with the expected demand over the next seven years, you’ll need to know all the latest techniques and analytical methods that could affect your SPE workflows. Here, Gilson discuss some of the latest considerations for your SPE processes...
Research labs are complicated environments and it is not always clear what can be done to improve sustainability. To date, most of the discussion around sustainability has focussed on the energy efficiency of instruments and equipment, such as fume hoods and cryogenic freezers. While this is important, it means that things like chemical and solvent selection are overlooked. Here Paul Vanden Branden, Director at SciMed, an exhibitor at Lab Innovations 2023 and member of the show’s advisory board, discusses...
Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative. Collaborating closely with the university’s veterinary practitioners, researchers aim to expand the number of canine NGS datasets, in a bid to advance our understanding of the biological progression of tumors...
Advances in technology mean that moving from microscopes to digital alternatives can now be achieved without sacrificing image quality. But this isn’t about the technology. Professor Gina Zini, reflects on the key benefits of digital developments, including better quality screening, saved time for busy morphologists, better clinical collaboration, improved training, and sharing expertise with developing countries...
Powders are used in all production processes of solid dosage forms like tablet or dry powder inhaler (DPI) manufacturing processes. Among all the powder properties, permeability, which is the capacity of a fluid (air) to pass through a powder bed, plays a crucial factor in different pharmaceutical processes. In the die filling of tablet manufacturing, the permeability determines the powder flowability during the displacement of the powder within the die and the capacity of the powder to pack in the die...
The International Space Station (ISS) National Laboratory is collaborating with NASA on a solicitation to advance research on cancer and other diseases. ISS National Lab Research Announcement (NLRA) 2023-10: Igniting Innovation: Science in Space to Cure Disease on Earth, in partnership with NASA’s Biological and Physical Sciences Division, will offer resource allocation and up to $5 million in total funding for an expected two to four awards for multiflight translational and transformative research and technology development projects...
New study shows that graphene-based TENGs could finally unlock nature’s wasted energy. Scientists may have finally found a solution to effectively harvesting energy from humans into electrical energy. Researchers from the Institute of Thin Films, Sensors and Imaging (ITFSI) from the University of the West of Scotland (UWS) explored the use of the 3D graphene foam material Gii™ by Integrated Graphene as an active layer in an energy generator (known as a TENG)...
AMSBIO, a leading supplier of human cell lines and research tools, is proud to announce its collaboration with WARR Space Labs, a student group from the Technical University of Munich (TUM). The students undertook an exciting project aimed at advancing our understanding of neurodegenerative disorders, particularly Alzheimer’s disease, through spaceborne experiments.
Biotech Fluidics has published a practical review paper that demonstrates how its MarvelX™ and MarvelXACT™ high pressure fluidic connections enable users to achieve reliable, repeatable, and consistent UHPLC performance. In this paper, fluidic experts explore the connection challenges facing users of modern UHPLC instruments. One of the biggest challenges in designing high performance fluidic connections for UHPLC is ensuring a reliable seal at the bottom of the connection port...
Agilent Technologies Inc. has announced the opening of a new full-scale Integrated Biology Center located at Monash University in Malaysia, focused on building local capabilities to accelerate research and development (R&D) in the field of science. The inauguration was held in conjunction with the company’s Academia-Industrial Day 2023, hosting distinguished guests from the research community...
Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...
LEEUWENHOEK’S THIRD CENTURY - Revealing the Sights of the Seventeenth Century by Brian J Ford Hon FRMS, Hon FLS. There was much excitement around the world when I revealed one of the most extraordinary revelations of my entire academic life – the original microscope specimens, prepared by Antony van Leeuwenhoek in the 1600s, had survived intact. They lay secure in folded paper envelopes hidden among his letters to London, and carefully preserved at the Royal Society...
PacBio, a leading developer of high-quality, highly accurate sequencing solutions and GeneDx, a leader in delivering improved health outcomes through genomic and clinical insights, have announced a research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions...
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus...
When working within a life sciences laboratory one of the most important assets is your samples. This is why it is imperative to preserve, store and retrieve samples while maintaining their integrity. With any large store or “library” of compounds or other samples, being able to easily retrieve a specified sub-set of samples is key to any research workflow - this is the so-called “pick list.” A new technical paper from Ziath describes how their Mirage 2D tube rack reader and Mohawk semi-automated tube picker...
To enhance the reproducibility of flow chemistry scale-up - precise control of mixing and temperature in highly exothermic or rapid reactions in particular is essential. The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent. Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Axis Healthcare, a family-run care facility in Oklahoma, has introduced VOYAGER adjustable tip spacing pipettes from INTEGRA Biosciences into its PCR laboratory workflows. These multichannel pipettes offer the laboratory a straightforward and easy-to-use liquid handling solution to provide accurate and high throughput testing as part of a holistic strategy to support patients in overcoming opioid addiction...
A team of scientists, from the University of Bath’s Department of Chemistry and Institute for Sustainability have found a way to create two of the world’s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry. It is perhaps not widely known that many common pharmaceuticals are manufactured using chemical precursors derived from crude oil, presenting a niche sustainability challenge as the world targets Net Zero...
A new six-month science expedition in low Earth orbit (LEO) begins when four astronauts launch to the International Space Station (ISS) as part of NASA’s SpaceX Crew-7 mission. While onboard the space station, the Crew-7 astronauts, who will be part of Expeditions 69 and 70, will perform a variety of investigations sponsored by the ISS National Laboratory. This 7th rotational crewed mission from SpaceX, which is part of NASA’s Commercial Crew Program, is scheduled to launch from NASA’s Kennedy Space Center in Florida...
Promega scientists contribute to new research to improve precision and efficiency of groundbreaking gene editing technique. A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing. The results demonstrate how this groundbreaking technique can be enhanced by using two inhibitors to boost insertion rates and reduce off-target effects...
Growing demand for analytical laboratory services (and the impact of the COVID-19 pandemic) will see the industry grow globally to about $492 million by 2027. Batch Release Testing shows the biggest growth in the market, estimated to increase at 9% Compound Annual Growth Rate (CAGR). To keep up with the expected demand over the next seven years, you’ll need to know all the latest techniques and analytical methods that could affect your SPE workflows. Here, Gilson discuss some of the latest considerations for your SPE processes...
Research labs are complicated environments and it is not always clear what can be done to improve sustainability. To date, most of the discussion around sustainability has focussed on the energy efficiency of instruments and equipment, such as fume hoods and cryogenic freezers. While this is important, it means that things like chemical and solvent selection are overlooked. Here Paul Vanden Branden, Director at SciMed, an exhibitor at Lab Innovations 2023 and member of the show’s advisory board, discusses...
Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative. Collaborating closely with the university’s veterinary practitioners, researchers aim to expand the number of canine NGS datasets, in a bid to advance our understanding of the biological progression of tumors...
Advances in technology mean that moving from microscopes to digital alternatives can now be achieved without sacrificing image quality. But this isn’t about the technology. Professor Gina Zini, reflects on the key benefits of digital developments, including better quality screening, saved time for busy morphologists, better clinical collaboration, improved training, and sharing expertise with developing countries...
Powders are used in all production processes of solid dosage forms like tablet or dry powder inhaler (DPI) manufacturing processes. Among all the powder properties, permeability, which is the capacity of a fluid (air) to pass through a powder bed, plays a crucial factor in different pharmaceutical processes. In the die filling of tablet manufacturing, the permeability determines the powder flowability during the displacement of the powder within the die and the capacity of the powder to pack in the die...
The International Space Station (ISS) National Laboratory is collaborating with NASA on a solicitation to advance research on cancer and other diseases. ISS National Lab Research Announcement (NLRA) 2023-10: Igniting Innovation: Science in Space to Cure Disease on Earth, in partnership with NASA’s Biological and Physical Sciences Division, will offer resource allocation and up to $5 million in total funding for an expected two to four awards for multiflight translational and transformative research and technology development projects...
New study shows that graphene-based TENGs could finally unlock nature’s wasted energy. Scientists may have finally found a solution to effectively harvesting energy from humans into electrical energy. Researchers from the Institute of Thin Films, Sensors and Imaging (ITFSI) from the University of the West of Scotland (UWS) explored the use of the 3D graphene foam material Gii™ by Integrated Graphene as an active layer in an energy generator (known as a TENG)...
AMSBIO, a leading supplier of human cell lines and research tools, is proud to announce its collaboration with WARR Space Labs, a student group from the Technical University of Munich (TUM). The students undertook an exciting project aimed at advancing our understanding of neurodegenerative disorders, particularly Alzheimer’s disease, through spaceborne experiments.
Biotech Fluidics has published a practical review paper that demonstrates how its MarvelX™ and MarvelXACT™ high pressure fluidic connections enable users to achieve reliable, repeatable, and consistent UHPLC performance. In this paper, fluidic experts explore the connection challenges facing users of modern UHPLC instruments. One of the biggest challenges in designing high performance fluidic connections for UHPLC is ensuring a reliable seal at the bottom of the connection port...
Agilent Technologies Inc. has announced the opening of a new full-scale Integrated Biology Center located at Monash University in Malaysia, focused on building local capabilities to accelerate research and development (R&D) in the field of science. The inauguration was held in conjunction with the company’s Academia-Industrial Day 2023, hosting distinguished guests from the research community...
Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...
LEEUWENHOEK’S THIRD CENTURY - Revealing the Sights of the Seventeenth Century by Brian J Ford Hon FRMS, Hon FLS. There was much excitement around the world when I revealed one of the most extraordinary revelations of my entire academic life – the original microscope specimens, prepared by Antony van Leeuwenhoek in the 1600s, had survived intact. They lay secure in folded paper envelopes hidden among his letters to London, and carefully preserved at the Royal Society...
PacBio, a leading developer of high-quality, highly accurate sequencing solutions and GeneDx, a leader in delivering improved health outcomes through genomic and clinical insights, have announced a research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions...
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus...
When working within a life sciences laboratory one of the most important assets is your samples. This is why it is imperative to preserve, store and retrieve samples while maintaining their integrity. With any large store or “library” of compounds or other samples, being able to easily retrieve a specified sub-set of samples is key to any research workflow - this is the so-called “pick list.” A new technical paper from Ziath describes how their Mirage 2D tube rack reader and Mohawk semi-automated tube picker...
To enhance the reproducibility of flow chemistry scale-up - precise control of mixing and temperature in highly exothermic or rapid reactions in particular is essential. The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent. Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...