Onboard the International Space Station (ISS), the Extant Life Volumetric Imaging System, dubbed ELVIS, is not about resurrecting rock-n-roll legends but pioneering scientific discovery. Using innovative holographic technology to deliver detailed 3D views of cells and microbes, the system allows scientists to study the adaptability and resilience of life under extreme conditions. Knowledge gained could reveal how life might persist on distant moons and planets, significantly enhancing our search for life outside Earth...
This Application Note presents an optimised SEC-MS method for the high-performance separation and characterisation of a single-chain variable fragment (scFv) and its drug conjugates (FDC). Using a bioinert PEEK-lined YMC-Pack Diol-120 metal-free column combined with MS compatible conditions delivers sharp peaks & precise resolution, enhanced signal response and reliable results. Boost your analytical expertise – download the Application Note now!...
TESTA Analytical reports a major polymer manufacturer is using their COMBO-ONE detector, as part of a GPC/SEC system, to characterize the structure of macromolecules that offer desirable performance properties. The client is a leading European manufacturer of high-performance water-soluble polymers for industrial applications. These polymers, although presenting a similar molecular weight and molecular weight distribution, have different physical structures which influence their performance in the target application...
Illumina Inc. and Nashville Biosciences, LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), have announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative. Insights from the AGD database are being leveraged to accelerate drug target discovery, therapeutic research and clinical development...
New alliance for advanced biological imaging aimed at enhancing some of the world's most innovative structural cell biology capabilities to help scientists answer pressing research questions. Thermo Fisher Scientific Inc., the world leader in serving science, has announced a Technology Alliance Agreement with the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute). This agreement aims to develop new technologies to enable researchers to better visualize human cells, significantly advancing scientific research and discovery...
Scientists at the Technical University of Munich (TUM) have developed a method that relies on physics rather than conventional chemistry to obtain the proteins that are needed for this purpose. Using short-wave, UV light invisible to humans, they have succeeded in purifying proteins from cell extracts or cultures. This technique is more efficient and gentler than previous methods...
Scientists at Novo Nordisk in Denmark have applied flow chemistry to enhance the cleavage of oligonucleotides. Utilising Vapourtec’s R-Series flow chemistry system to undertake their research, the Novo Nordisk team have made the data available in an application note that will be of interest to all chemists exploring oligonucleotides. The improvements reported include a reduction in the time for cleavage and complete deprotection to less than 3 minutes...
Scientific Laboratory Supplies (SLS) and Grant Instruments have produced a case study aiming to bring greater transparency to product sustainability. Whilst qualitative insights provide a strong foundation, data-driven sustainability requires measurable carbon data. This case study explores how collaboration can help laboratories make informed purchasing choices by assessing the full environmental impact of a product’s lifecycle...
A new study by EMBL researchers has shown how chromosomes change shape during cell division. Certain protein complexes help fold DNA into overlapping loops that repel each other, which then stack to create a rod-like structure. This is the first time scientists have directly observed an entire chromosome in high resolution within a dividing cell, offering new insights into how chromosomes are formed...
With critical deadlines approaching for the 2026–2031 Nationally Determined Contributions (NDCs), countries are under increasing pressure to deliver stronger climate commitments. As key pillars of the Paris Agreement, NDCs outline each nation's targets for reducing emissions and advancing sustainability efforts. Here, Kate Vanderburgh, Sr. Product Specialist, Thermo Fisher Scientific, explains how electron microscopy (EM) drives material innovation to support sustainable, low-carbon technologies to combat climate change...
INTEGRA Biosciences has played a pivotal role in advancing the field of serological pipetting over the last 40 years, and has just created a fascinating article covering the fast-paced history of serological pipet controller development. This interesting and educational resource is available to read now on INTEGRA’s website, and provides a concise overview of the advances that have shaped the field in the last few decades...
The demand for faster and more reliable cannabinoid analysis is growing with the expanding use of medicinal cannabis. Traditional HPLC methods often fall short in resolution due to the similar structures of cannabinoids. This application note presents a rapid UHPLC method using the YMC-Triart C18 ExRS column, delivering high-resolution separation of 11 cannabinoids in less than 6 minutes. Optimised for challenging separations, this column ensures efficiency without compromising accuracy...
Specialised Imaging reports that the Dlott group in the Department of Chemistry at the University of Illinois (Urbana, USA) are using a SIMX8 ultra high-speed framing camera adapted to study high-speed impact phenomena using multispectral imaging to analyse emitted wavelengths. By using hyperspectral techniques, researchers are seeking to identify and characterize materials based on their unique spectral signatures...
In the development and analysis of advanced materials, the interplay between surface chemistry and structural properties is essential for understanding material behaviour. However, since several different methods — such as scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) — may need to be used, ensuring that data is obtained from the same regions of interest is vital. Here, Christopher Deeks, Channel Manager XPS at Thermo Fisher Scientific, explores how implementing a Correlative Imaging and Surface...
Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain. Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease. A new study from EMBL Heidelberg researchers shows that gut bacteria can bring about profound molecular changes in one of our most critical organs – the brain...
Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists at Novo Nordisk in the C-terminal α-amination of peptides and proteins from cysteine-extended polypeptide precursors. Published in a paper in Nature Communications entitled ‘Photochemically-enabled, post-translational production of C-terminal amides’, the process involved three steps...
Metrohm USA is proud to announce the winner of the 2025 Young Chemist Award, Ms. Elham Akbari, a graduate student from Temple University. This year’s award, increased to $15,000 to reflect Metrohm’s growing commitment to fostering scientific innovation, honors Ms. Akbari’s outstanding research on thermal treatment methods for the destruction of per- and polyfluoroalkyl substances (PFAS), often referred to as "forever chemicals...
INTEGRA Biosciences offers liquid handling solutions and magnetic modules to streamline every stage of NGS sample preparation. These innovative tools help to reduce errors, improve the precision and reliability of sequencing data, and provide more efficient processes. NGS is a high throughput technology that rapidly sequences large volumes of DNA or RNA, enabling comprehensive analysis of genetic material for applications like genomics, transcriptomics and personalized medicine...
Aston Institute for Membrane Excellence (AIME) has received a £500,000 grant from the Wolfson Foundation to purchase an ultrafast confocal spinning disc microscope. This instrument will accelerate AIME research, led by Professor Roslyn Bill, into treatments for dementia and other forms of cognitive decline. An ultrafast spinning disc confocal microscope enables faster, higher-resolution images of biological processes than is currently possible at AIME...
Engineers from The University of Warwick’s Integrative Synthetic Biology Centre and Imperial College London’s Department of Bioengineering have unveiled how to engineer microbial ‘cell-factories’ to boost the manufacture of high-value chemicals that are used in everyday products like domestic goods, clothes and food. To date cell-based systems have been less efficient than existing petrochemical processes due to natural constraints within living cells...
Did you know some viruses don’t cause illness and can instead be used to treat disease? Biotechnology startup Axonis Therapeutics reprogrammed a virus to carry a novel gene therapy to neurons to treat neurological conditions like Alzheimer’s, Parkinson’s, and spinal cord injury. The company needed a way to test the therapeutic in a mature human brain model, which is difficult to produce on Earth...
Leading science and innovation campus, Discovery Park, in Sandwich, Kent has launched applications for the fourth cohort of its immersive business growth competition, ‘Discovery Spark’. Supported by Capital Enterprise Network and Cancer Research UK (CRUK), Discovery Park’s latest Discovery Spark programme will have an oncology theme. It invites cancer tech start-ups looking to accelerate their business to apply...
Onboard the International Space Station (ISS), the Extant Life Volumetric Imaging System, dubbed ELVIS, is not about resurrecting rock-n-roll legends but pioneering scientific discovery. Using innovative holographic technology to deliver detailed 3D views of cells and microbes, the system allows scientists to study the adaptability and resilience of life under extreme conditions. Knowledge gained could reveal how life might persist on distant moons and planets, significantly enhancing our search for life outside Earth...
This Application Note presents an optimised SEC-MS method for the high-performance separation and characterisation of a single-chain variable fragment (scFv) and its drug conjugates (FDC). Using a bioinert PEEK-lined YMC-Pack Diol-120 metal-free column combined with MS compatible conditions delivers sharp peaks & precise resolution, enhanced signal response and reliable results. Boost your analytical expertise – download the Application Note now!...
TESTA Analytical reports a major polymer manufacturer is using their COMBO-ONE detector, as part of a GPC/SEC system, to characterize the structure of macromolecules that offer desirable performance properties. The client is a leading European manufacturer of high-performance water-soluble polymers for industrial applications. These polymers, although presenting a similar molecular weight and molecular weight distribution, have different physical structures which influence their performance in the target application...
Illumina Inc. and Nashville Biosciences, LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), have announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative. Insights from the AGD database are being leveraged to accelerate drug target discovery, therapeutic research and clinical development...
New alliance for advanced biological imaging aimed at enhancing some of the world's most innovative structural cell biology capabilities to help scientists answer pressing research questions. Thermo Fisher Scientific Inc., the world leader in serving science, has announced a Technology Alliance Agreement with the Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute). This agreement aims to develop new technologies to enable researchers to better visualize human cells, significantly advancing scientific research and discovery...
Scientists at the Technical University of Munich (TUM) have developed a method that relies on physics rather than conventional chemistry to obtain the proteins that are needed for this purpose. Using short-wave, UV light invisible to humans, they have succeeded in purifying proteins from cell extracts or cultures. This technique is more efficient and gentler than previous methods...
Scientists at Novo Nordisk in Denmark have applied flow chemistry to enhance the cleavage of oligonucleotides. Utilising Vapourtec’s R-Series flow chemistry system to undertake their research, the Novo Nordisk team have made the data available in an application note that will be of interest to all chemists exploring oligonucleotides. The improvements reported include a reduction in the time for cleavage and complete deprotection to less than 3 minutes...
Scientific Laboratory Supplies (SLS) and Grant Instruments have produced a case study aiming to bring greater transparency to product sustainability. Whilst qualitative insights provide a strong foundation, data-driven sustainability requires measurable carbon data. This case study explores how collaboration can help laboratories make informed purchasing choices by assessing the full environmental impact of a product’s lifecycle...
A new study by EMBL researchers has shown how chromosomes change shape during cell division. Certain protein complexes help fold DNA into overlapping loops that repel each other, which then stack to create a rod-like structure. This is the first time scientists have directly observed an entire chromosome in high resolution within a dividing cell, offering new insights into how chromosomes are formed...
With critical deadlines approaching for the 2026–2031 Nationally Determined Contributions (NDCs), countries are under increasing pressure to deliver stronger climate commitments. As key pillars of the Paris Agreement, NDCs outline each nation's targets for reducing emissions and advancing sustainability efforts. Here, Kate Vanderburgh, Sr. Product Specialist, Thermo Fisher Scientific, explains how electron microscopy (EM) drives material innovation to support sustainable, low-carbon technologies to combat climate change...
INTEGRA Biosciences has played a pivotal role in advancing the field of serological pipetting over the last 40 years, and has just created a fascinating article covering the fast-paced history of serological pipet controller development. This interesting and educational resource is available to read now on INTEGRA’s website, and provides a concise overview of the advances that have shaped the field in the last few decades...
The demand for faster and more reliable cannabinoid analysis is growing with the expanding use of medicinal cannabis. Traditional HPLC methods often fall short in resolution due to the similar structures of cannabinoids. This application note presents a rapid UHPLC method using the YMC-Triart C18 ExRS column, delivering high-resolution separation of 11 cannabinoids in less than 6 minutes. Optimised for challenging separations, this column ensures efficiency without compromising accuracy...
Specialised Imaging reports that the Dlott group in the Department of Chemistry at the University of Illinois (Urbana, USA) are using a SIMX8 ultra high-speed framing camera adapted to study high-speed impact phenomena using multispectral imaging to analyse emitted wavelengths. By using hyperspectral techniques, researchers are seeking to identify and characterize materials based on their unique spectral signatures...
In the development and analysis of advanced materials, the interplay between surface chemistry and structural properties is essential for understanding material behaviour. However, since several different methods — such as scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) — may need to be used, ensuring that data is obtained from the same regions of interest is vital. Here, Christopher Deeks, Channel Manager XPS at Thermo Fisher Scientific, explores how implementing a Correlative Imaging and Surface...
Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain. Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease. A new study from EMBL Heidelberg researchers shows that gut bacteria can bring about profound molecular changes in one of our most critical organs – the brain...
Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists at Novo Nordisk in the C-terminal α-amination of peptides and proteins from cysteine-extended polypeptide precursors. Published in a paper in Nature Communications entitled ‘Photochemically-enabled, post-translational production of C-terminal amides’, the process involved three steps...
Metrohm USA is proud to announce the winner of the 2025 Young Chemist Award, Ms. Elham Akbari, a graduate student from Temple University. This year’s award, increased to $15,000 to reflect Metrohm’s growing commitment to fostering scientific innovation, honors Ms. Akbari’s outstanding research on thermal treatment methods for the destruction of per- and polyfluoroalkyl substances (PFAS), often referred to as "forever chemicals...
INTEGRA Biosciences offers liquid handling solutions and magnetic modules to streamline every stage of NGS sample preparation. These innovative tools help to reduce errors, improve the precision and reliability of sequencing data, and provide more efficient processes. NGS is a high throughput technology that rapidly sequences large volumes of DNA or RNA, enabling comprehensive analysis of genetic material for applications like genomics, transcriptomics and personalized medicine...
Aston Institute for Membrane Excellence (AIME) has received a £500,000 grant from the Wolfson Foundation to purchase an ultrafast confocal spinning disc microscope. This instrument will accelerate AIME research, led by Professor Roslyn Bill, into treatments for dementia and other forms of cognitive decline. An ultrafast spinning disc confocal microscope enables faster, higher-resolution images of biological processes than is currently possible at AIME...
Engineers from The University of Warwick’s Integrative Synthetic Biology Centre and Imperial College London’s Department of Bioengineering have unveiled how to engineer microbial ‘cell-factories’ to boost the manufacture of high-value chemicals that are used in everyday products like domestic goods, clothes and food. To date cell-based systems have been less efficient than existing petrochemical processes due to natural constraints within living cells...
Did you know some viruses don’t cause illness and can instead be used to treat disease? Biotechnology startup Axonis Therapeutics reprogrammed a virus to carry a novel gene therapy to neurons to treat neurological conditions like Alzheimer’s, Parkinson’s, and spinal cord injury. The company needed a way to test the therapeutic in a mature human brain model, which is difficult to produce on Earth...
Leading science and innovation campus, Discovery Park, in Sandwich, Kent has launched applications for the fourth cohort of its immersive business growth competition, ‘Discovery Spark’. Supported by Capital Enterprise Network and Cancer Research UK (CRUK), Discovery Park’s latest Discovery Spark programme will have an oncology theme. It invites cancer tech start-ups looking to accelerate their business to apply...