Thermo Fisher Scientific is pleased to announce the introduction of new HPLC and UHPLC column, Thermo Scientific GlycanPac AXR-1 column, for glycan analysis.

This new column offers extremely high-resolution separations based on charge, isomerism, and size and are designed to facilitate both high resolution glycan profile characterization and quantification. Until now, glycans isomers could not be separated by conventional HPLC, said Ilze Birznieks, Product Marketing Manager for Biocolumns at Thermo Fisher. This new column helps users achieve greater resolution of glycans using HPLC, providing easier profile characterization...

Unlike standard parabolic mirrors, Off-Axis Paraboloids (OAP) direct and focus incident collimated light at a specific angle, allowing unrestricted access to the focal point as well as reducing the size and minimising the weight of an optical design.

Working with the highest quality optical glasses - Optical Surfaces Ltd. produce standard OAP from 60mm to 600 mm in diameter. Benefiting from a uniquely stable manufacturing environment, and a highly skilled team of engineers and craftsmen, Optical Surfaces is able to routinely produce OAPs with surface accuracy to lambda/20 (peak-to-valley) depending upon off-axis angles....

Thermo Fisher Scientific has developed a rapid and robust high-performance anion-exchange chromatography

With pulsed amperometric detection method for the accurate determination of common sugars in acid-hydrolyzed biomass samples with high carbohydrate concentrations. Application Update 192: Carbohydrate Determination of Biofuel Samples demonstrates that this approach has a linear range suitable for handling high-concentration biomass samples with minimal sample treatment. This new method is fast, provides good sensitivity, has consistent response, and can be routinely used to determine carbohydrates in the feedstock for biofuel production...

Raster Orbital Scanning Technology from Ocean Optics Recognised at TASIA Awards

The Raster Orbital Scanning (ROS) feature of the IDRaman family of products from Ocean Optics has been recognized as one of 2013’s 15 best innovation technologies by The Analytical Scientist magazine, an industry publication. ROS is a novel Raman spectroscopy sampling technique that helps to derive more accurate and comprehensive measurement results. The IDRaman mini handheld Raman spectrometer and the IDRaman reader integrated Raman spectrometer both feature ROS...

A technical article is available from Genevac that describes a rapid, safe technique for drying oligonucleotide and DNA samples.

DNA and oligonucleotide samples are sensitive and care needs to be exercised during concentration. Research done at the Welcome Trust Centre for Human Genetics (UK) shows that the Genevac EZ-2 evaporator is an ideal tool for concentrating SNP and oligonucleotides in microplates when preparing samples for microarraying and for Sequenon analysis. Compared to traditional methods, using the EZ-2 evaporator is shown to significantly speed up concentration rates, eliminate potential sources of damage to samples and also improve final sample quality...

Waters Introduces UPLC System for nano- to Microscale Separations – the ACQUITY UPLC M-Class System 

New UPLC System and Columns Drive Separations Efficiency and the Sensitivity of LC-MS Analyses to New Levels. Waters Corporation (WAT:NYSE) today introduced the new Waters® ACQUITY UPLC® M-Class System, an industry-first nano- to microscale UltraPerformance LC® (UPLC®) system rated for 15,000 psi operation. Coupled to Waters mass spectrometers, the system delivers the sensitivity to quantify and to identify vanishingly small concentrations of key molecules....

New patent for Spark Holland

Spark Holland B.V. is pleased to announce the publication of US patent no. US 8586382 B2 which relates to a method and an apparatus for desorption of a blood sample from a medical test sheet comprising at least one dried blood spot (DBS) for the purpose of biomedical analysis of the blood sample. The patent allows that the new method eliminates the need for first punching out a disc area of the test sheet containing dried blood sample, thus speeding up the procedure considerably and that on-line desorption of dried blood spots is faster and easier and allows for further automation of the process.

Bruker releases application note for analysis of sulfonamides in honey using Bruker’s Advance EVOQ Elite LC-MS/MS system

Bruker Chemical and Applied Markets (CAM), Fremont, California, US: Bruker releases application note for analysis of sulfonamides in honey using Advance EVOQ Eliteruker has released an application note detailing a simple, fast and robust method developed for the quantitation of sulfonamides in honey, using Bruker’s EVOQ Elite triple quadruple liquid chromatography mass spectrometer (LC-MS/MS). Sulfonamides are a group of broad spectrum antibacterial drugs, used to prevent and treat bacterial growth in honey products...

Spark Holland OEM agreement includes patented DBS technology

Spark Holland B.V. and GERSTEL GmbH & Co. KG have announced an OEM agreement based on Spark’s patented dried blood spot (DBS) technology which recently received a US patent (US 8586382 B2). The OEM agreement includes the use of Spark’s innovative FTD™ technology and the Spark DBS Autosampler™, allowing GERSTEL to develop and market fully integrated automated DBS systems....

Spectrometer delivers market-best sensitivity and performance

The QE Pro from Ocean Optics is a high-sensitivity, back-thinned CCD array spectrometer with outstanding quantum efficiency, wide dynamic range and extremely low noise operation for applications with low light levels and where wide concentration ranges are measured. The QE Pro's optical design maximizes performance for a range of application needs. With its 18-bit A/D, QE Pro has dynamic range performance that makes it the highest sensitivity miniature spectrometer available today....

Thermo Fisher Scientific has developed a reproducible and accurate high-performance liquid chromatography (HPLC) method combined with on-line solid-phase extraction for the sensitive determination of carbendazim in orange juice.

Application Note 1067: Determination of Carbendazim in Orange Juice demonstrates that this application—performed using a rapid separation liquid chromatography system—simplifies sample preparation and improves HPLC detection sensitivity with a method detection limit of carbendazim in orange juice of 0.2 μg/L. Although carbendazim is a fungicide used in many countries to improve crop production....

Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, will be launching the µDAWN™ at Pittcon 2014

The µDAWN is the world’s first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins or other biopolymers directly, without resorting to column calibration or reference standards. Wyatt Technology’s µDAWN connects to the Optilab® UT-rEX™, the first refractive index detector for UHPLC....

The application of morphologically directed Raman spectroscopy to characterizing the component-specific particulate properties of the active components in a topical pharmaceutical cream is described in an application note from Malvern Instruments.

Scientists all over the world have been monitoring the statistical distribution of weather patterns over extended periods of time to measure the potential affects and significance of climate change.

This research not only studies past fluctuations, but also is used to predict future shifts in our climate and its global environmental impact. The British Antarctic Survey (BAS) is a leading environmental research center that focuses on the United Kingdom’s national scientific activities in Antarctica. Some of their current research includes long-term monitoring of global climate change via ice core sample analysis of the polar ice caps....

Edinburgh Instruments is pleased to announce the US launch of a new, low-cost, high performance fluorescence spectrometer at BioS 2014 and Photonics West 2014, 1-6 February 2014.

Edinburgh instruments will demonstrate the operational capabilities of the analytical instrument live at the shows. A fully integrated steady state spectrometer with single photon sensitivity, the FS5 is designed for the research and analytical market. It has a number of features that are unique in its class of fluorescence spectrometers, including: Single photon sensitivity. High data acquisition speed and High Dynamic Range. Comprehensive yet easy to operate software...

The FDA conforming WinASPECT^® PLUS software for the SPECORD^® PLUS series of Analytik Jena offers the ideal tool needed for efficient analysis in all fields, from R&D to production, from quality control to lab routine.

Industries like pharmacy, biotechnology and medicine are subject to strict requirements of regulatory authorities. The Food and Drug Administration (FDA) is the supreme authority for consumer protection of the USA. They establish the requirements for recording and electronical signatures of data, which are defined in the 21 CFR (Code of Federal Regulations) Part 11....

Markes International (Llantrisant, UK), a world leader in instrumentation for trace organic analysis, has announced the launch of a variable-energy electron ionisation source technology for GC–MS, Select-eV®.

By enabling the energy of ionising electrons to be changed, Select-eV breaks new ground in the field of GC–MS. It allows the production of reference-quality electron ionisation mass spectra with conventional full-fragmentation patterns, and repeatable ‘soft-ionisation’ spectra exhibiting reduced fragmentation and an enhanced molecular ion. Previous attempts to develop soft electron ionisation have been compromised by a dramatic drop in sensitivity.....

ACE UltraCore is a new range of ultra-inert solid-core (superficially porous) particle UHPLC/HPLC columns from Advanced Chromatography Technologies Limited. The monodisperse particle distribution of these phases combines high efficiency and performance, with a low column back pressure, to deliver exceptional chromatography. 

J. G. Finneran’s Ultra Low Bleed Aluminum Seals and 9mm R.A.M.^TM  Caps

J. G. Finneran’s Ultra Low Bleed Aluminum Seals and 9mm R.A.M.^TM  Caps are lined using an  LCMS high purity septa. This septa is ideal for very sensitive applications such as Mass Spec or when multiple injections are required.  Our Ultra Low Bleed Septa eliminates particulates with no interfering peaks.

The 6850 UV/visible spectrophotometer is Jenway’s first double-beam instrument with a variable spectral bandwidth – of 5nm down to 0.5nm.

This new instrument has highly stable optics and is particularly well-suited for use in laboratories where compliance to multiple regulatory agencies is required. The double beam optics and two detectors measure the sample and reference simultaneously for optimum measurement accuracy and stability over long periods of time. The 6850 has a variable spectral bandwidth of 0.5nm, 1nm, 2nm, 4nm and 5nm, giving flexibility whilst ensuring compliance to European Pharmacopeia requirements. The narrow spectral bandwidth ensures improved resolution.

Gas Chromatography Options Designed to Conserve Helium, Boost Flexibility, Add Usability

Scientists using gas chromatography (GC) can enjoy a number of new options with the Thermo Scientific TRACE 1300 Series GC system, designed to conserve helium, permit use of multiple detectors simultaneously, automate sampling gas workflows, and perform flame photometric detection. New options for the TRACE 1300 Series GC platform include...

The HT-4X centrifugal evaporator from Genevac provides optimised sample preparation capabilities for scientists working in the drug discovery environment. 

Built to the highest specifications, the HT-4X makes demanding applications routine.  Corrosive vapours such as trifluoroacetic acid may be removed by the standard system and an inert purge option allows high safety evaporation of flammable solvents. In addition, the HT-4X can also be used to achieve high speed lyophilisation of HPLC fractions and solvents used for reformatting samples. The HT-4X is a high performance evaporator that combines ease of use, compactness, operational versatility and efficient sample processing...