A new study has shown the power of genetic testing to pick out the best drugs for children with cancer to extend and improve their lives – signalling a new era of precision medicine for young patients. The pilot including more than 200 children found that half had gene mutations that are targetable by adult cancer drugs that are either available as standard treatment or via clinical trials....
A2LA is pleased to announce both the accreditation of Demeter Laboratory and the renewal of accreditation of Galbraith Laboratories, Inc. to ISO/IEC 17025:2017 for cannabis testing. Demeter Laboratory, located in Oklahoma City, Oklahoma, and Galbraith Laboratories, located in Knoxville, Tennessee, are each their first cannabis testing laboratories accredited within their respective states....
Markes International Ltd, Llantrisant-based manufacturer of world-leading scientific laboratory instrumentation for detecting very small amounts of chemicals, has officially received its two Queen’s Awards for Enterprise. Markes is one of only of 10 Welsh companies to receive an award and one of only 6 British companies to be recognised in two categories. The Awards were presented by the Lord Lieutenant of Mid Glamorgan...
Peak Analysis & Automation (PAA), a global leader at the heart of laboratory automation, has released a series of new application notes demonstrating the versatility and flexibility of its benchtop S-LAB™ automated plate handler. The S-LAB is PAA’s entry-level automation solution, designed to easily enable multiple applications for faster scientific breakthroughs....
A classic boxing move, the ‘one-two punch’, could also be effective against cancer: a left jab knocks cancer cells senseless, quickly followed by a right hook that knocks them out altogether. Researchers at the Netherlands Cancer Institute have shown that cancer cells are vulnerable to this kind of approach. “This is a beautiful, universal principle, that could be used for all forms of cancer.” On October 2nd the researchers publish their results in Nature....
Source new technologies, future-proof your laboratory and find out ways to make procurement sustainable. Lab Innovations, the UK’s only trade show dedicated to the laboratory industry, will showcase at Birmingham’s NEC, 30 & 31 October, multiple options to help visitors future-proof their laboratories - from innovative products, to waste reduction (time included!) and sustainability....
Research published in Nature by the Korea Advanced Institute of Science (KAIST) found that lymphatic vessels in the scull involved in the clearance of cerebrospinal fluid often become compromised with age. This finding was only possible through advances in imaging technology. Using MR Solutions’ 3T/17 preclinical liquid-helium free MRI system the KAIST researchers observed how the meningeal lymphatic vessels (mLVs), mainly in the basal part of the skull...
UK-based scientists have engineered plants to produce an oil that mimics the chemical structure of human milk fat, a major component of breast milk. Previous studies suggest the human form of this molecule, triacylglycerol, aids absorption of key nutrients by the infant gut, but few infant formulas contain anything like it. Now a team from Rothamsted Research have found a way to modify the biochemical pathways of plants so they can produce the human form of this key nutrient....
The HD-X - the very latest fully automated technology platform from Quanterix for developing and performing digital immunoassays – has been unveiled at LGC’s GLP/GCP-accredited lab in Fordham, near Cambridge, UK. The HD-X builds on the success of the HD-1 analyser in conveying unprecedented levels of sensitivity, robustness, and throughput to Pharmacokinetic-Pharmacodynamic (PK-PD) bioanalytical studies....
EKF Diagnostics, the global in vitro diagnostics company, announces that it has opened a new Research & Development facility at its Cardiff, UK headquarters. The new Special Projects Laboratory will focus on developing new applications for EKF’s many point-of-care and central laboratory medical products to enable the Company to enter new market sectors, as well as providing additional diagnostics sales and regulatory support....
From its beginnings at the University of Oxford in 2016, Arctoris has established the world’s first fully automated, robotic laboratory dedicated to drug discovery, providing global drug discovery teams with on-demand access to a broad range of cellular, molecular and biochemical assays. The company’s automated system delivers high-quality data through standardised, pre-optimised and fully validated processes, while its innovative online portal makes it easy for researchers to plan, order and track their experiments from anywhere in the world....
Illumina, Inc. and the Broad Institute of MIT and Harvard have announced they have entered into a collaboration for the co-development of secondary genomic analysis algorithms and software. Top data scientists from both institutions will collaborate to bring together the industry-leading open-source GATK algorithms with the speed and enhanced accuracy of Illumina’s DRAGEN™ (Dynamic Read Analysis for GENomics) Bio-IT Platform for commonly used methods....
What’s the difference between High Performance Liquid Chromatography (HPLC) and Ion Chromatography (IC)? What are the capabilities and limitations of each technique? Knowing these differences can actually make a huge difference. As a proven, robust and highly versatile technique, IC can help HPLC users extend their analytical capabilities tremendously. Our free white paper compares the two methods systematically focusing on the strengths of ion chromatography....
St George Street Capital (SGSC), a UK registered charity, has signed a license agreement with AstraZeneca to develop two compounds in the clinic: one for idiopathic male infertility, and the other for renal transplant rejection. The agreement enables additional compounds to be added in the future...
Provepharm Life Solutions, a laboratory specializing in molecule revitalization, built this 500m2 pilot plant within a 3,000m2 production site in order to produce the group’s active pharmaceutical ingredients (APIs) in an environment that meets the most demanding international requirements. When the first quantities are synthesized, it will allow the company to fill applications...
The space occupied by a drug molecule in three dimensions, and how it fits into the target, is an important consideration when designing a new compound that might become a drug. Medicinal chemists commonly use 3D rendering software to visualise the shape of molecules by creating chemical structures they can rotate on a flat computer screen using a mouse or trackpad. But what if they could manipulate them in three dimensions instead, while still being able to see and interact with their colleagues?...
Agilent Technologies Inc. has announced that Professor Hualiang Jiang has received an Agilent Thought Leader Award. Professor Jiang directs the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences and is a leading researcher in the area of medicinal chemistry and computational drug design. Professor Jiang has a strong track record identifying new targets for cancer therapy and designing inhibitors that block protein-protein interactions.....
This will be celebrated with an event welcoming back high-calibre Award Alumni to talk about their science and careers: The Young European Investigators Conference held at the EMBL Advanced Training Centre in Heidelberg, on June 25, 2020. This free one-day conference is open to all scientists in biomedical research. The scientific program is organized by former winners Simon Boulton (The Francis Crick Institute, United Kingdom) and Óscar Fernández-Capetillo (CNIO, Spain & Karolinska Institute, Sweden)....
E-commerce platform serves scientists by providing a wide selection of compounds from trusted worldwide suppliers for easy search, convenient ordering and hassle-free delivery. MolPort, a dedicated full-service e-commerce platform with extensive expertise in compound sourcing, recently announced its expansion into the US with the opening of MolPort Inc. This new business unit will further streamline the compound ordering process for its many US customers...
Verder Scientific has formally agreed to acquire all shares of the Chinese company EZ-mat and become its sole owner. Verder Scientific is a division of the Verder Group, a family owned group of companies already deeply engaged and well reputed in the global development, manufacturing and distribution of products and services of state-of-the-art scientific applications....
Online platform for freelance scientists, Kolabtree, is the first specialist science platform to surpass 10,000 registered freelancers. The company is more equipped than ever to enable access to the specialist skills required for projects, such as analyzing data, designing a clinical trial, helping with regulatory approval or scientific writing. These skills help businesses to develop new products, conduct robust research and grow their businesses...
Prof. Mark Leake - University of York will present "Molecular precise optical microscopy for complex biological questions." Other leading researchers in the field will be giving presentations on a range of related topics, including novel, spectroscopy, nanoscale imaging, biomedical applications of novel microscopy techniques, image analysis and imaging frontiers. They will showcase the vibrant research and state-of-the-art in these areas...