In the development and analysis of advanced materials, the interplay between surface chemistry and structural properties is essential for understanding material behaviour. However, since several different methods — such as scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) — may need to be used, ensuring that data is obtained from the same regions of interest is vital. Here, Christopher Deeks, Channel Manager XPS at Thermo Fisher Scientific, explores how implementing a Correlative Imaging and Surface...
Leica Microsystems, a leader in microscopy and scientific instrumentation and advanced imaging solutions, has announced that it has acquired ATTO-TEC, a leading specialty supplier of fluorescent dyes and reagents. The addition of dyes and reagents for sample preparation complements the renowned Leica portfolio of microscopy imaging platforms and advanced AI-based analysis software...
Agilent Technologies Inc. has announced the Agilent IDP-35 and IDP-45 dry scroll pumps, designed to provide quiet, efficient, oil-free, and worry-free vacuum solutions for applications requiring higher pumping capacity. Consistent with the high standards of all Agilent IDP scroll pumps, the new IDP-35 and IDP-45 pumps offer several key benefits to customers. These pumps are ideal for applications needing higher pumping capacity without the drawbacks of oil-sealed pumps...
Hitachi High-Tech Europe has introduced the SU3800SE and SU3900SE Schottky field emission scanning electron microscopes (SEMs) to offer fully automatic optical alignment, allowing high-resolution results to be achieved quickly and easily by any user. The large sample handling and variable pressure operation means they can accommodate a wide range of sample types, and the powerful automation tools enable easy acquisition of large datasets...
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Invitrogen™ EVOS™ S1000 Spatial Imaging System. This advanced system addresses the limitations of current fluorescent microscopy technologies by enabling researchers to generate a multiplexed high-quality image for multiple samples within several hours, thereby lowering the barrier to entry into spatial tissue proteomics...
Say hello to our newest, fastest and most intuitive imaging solution - providing deeper insights for every lab. Empower your team to quickly obtain high-definition images and robust data from a wide range of 2D and 3D cell assays - and upgrade the system as your research needs evolve.The ImageXpress HCS.ai system features a modular design and a wide array of configuration options, allowing for customization to meet your current needs and on-site upgrades as your requirements evolve - eliminating the need to purchase a new system...
Aston Institute for Membrane Excellence (AIME) has received a £500,000 grant from the Wolfson Foundation to purchase an ultrafast confocal spinning disc microscope. This instrument will accelerate AIME research, led by Professor Roslyn Bill, into treatments for dementia and other forms of cognitive decline. An ultrafast spinning disc confocal microscope enables faster, higher-resolution images of biological processes than is currently possible at AIME...
In materials science, achieving precise and repeatable scanning electron microscopy (SEM) analysis requires pristine sample surfaces. However, handling and preparation methods frequently degrade the sample’s condition, making it challenging to observe the material's essential features. Here, Britta Siefer, SEM expert at Thermo Fisher Scientific, explains how a reliable workflow can preserve sample integrity for quality analysis...
Leica Biosystems, a global leader in anatomic and digital pathology solutions; and Indica Labs, a global leader in artificial intelligence (AI)-powered digital pathology software, have announced that Leica Biosystems has agreed to make a significant strategic investment in Indica Labs. This partnership has the potential to accelerate AI-enabled companion diagnostics (CDx) and support discoveries and treatments based on discrete or complex biomarker expression profiles which are not discernable by the human eye.
Physicists are getting closer to controlling single-molecule chemical reactions – could this shape the future of pharmaceutical research? A new study, published in the prestigious journal Nature Communications, set out to demonstrate for the first time that competing chemical reaction outcomes can be influenced by using the atomic resolution of a scanning tunnelling microscope (STM).
ZEISS partners with Mindpeak, a pioneer in AI-powered pathology solutions, to develop an integrated Multiplex Immunofluorescence (mIF) solution that serves pathologists across research, diagnostics, and clinical applications. Mindpeak’s expertise in AI-based image analysis of pathological tissues, particularly through its established algorithms for clinical routine applications, complements ZEISS's advanced instruments and software for research applications of mIF...
Conducting quality control analysis in-house can offer time-saving benefits and help to control costs and protect confidential information. However, for companies that are not experienced in selecting an appropriate microscope, outsourcing SEM capabilities to a university or laboratory can be a tempting option. Here, Robbie O’Connell, Sales Account Manager (Electron Microscopy) at SEM specialist Thermo Fisher Scientific, offers advice on what to look for when purchasing an SEM for quality control purposes...
Queensgate and the United Kingdom's National Metrology Institute have revealed their latest breakthrough at Euspen’s Special Interest Conference: Precision Motion Systems and Control in November. The development is a novel control system for a two-axis flexure stage with a 100 µm x 100 µm scanning range that enables high-speed atomic force microscopy (HS-AFM) over large areas. The result is an HS-AFM system capable of imaging large areas with molecular-level resolution...
Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers have captured a real-time molecular movie to show how two essential cellular processes – transcription and translation – interact with each other in bacteria...
Bruker Corporation announces the launch of the Dimension Nexus™ atomic force microscope (AFM). Dimension Nexus is the newest addition to the industry‑leading Dimension® AFM product line, which has had more than 4600 systems installed around the world. With the latest‑generation NanoScope® 6 controller, this new small‑footprint AFM delivers wider access to Bruker’s exclusive PeakForce Tapping® technology and over 50 AFM modes...
Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists seeking to harness the utility of the GFP (green fluorescent protein) tag. GFP is a common fusion protein tag that enables protein expression to be monitored, quantified, and localized within the complex environment of the cell...
TESCAN Group has reopened its existing Tempe R&D facility, adding a laboratory showcasing TESCAN’s latest electron microscopy technologies. The lab features the TESCAN TENSOR STEM and the newly launched Solaris 2 FIB-SEM, offering customers hands-on demonstrations and specialized support in sectors such as Materials Science and Semiconductor R&D, Failure Analysis and Process Monitoring...
Evident recently announced the release of its IXplore™ IX85 automated inverted microscope system. With an industry-leading 26.5mm field number (FN), combined with new advanced imaging tools that ensure clear, accurate results, this new system empowers researchers to capture more data and uncover new insights faster than ever before. It also delivers an unmatched level of customizability, allowing users to design or build an intelligent, high-performance imaging platform that meets their specific goals...
CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy, and Tomocube, a leader in holotomography (HT) technology, today announced a strategic collaboration to provide a next-generation multimodal imaging platform, the HT-X1™ Plus. By combining the expertise of both companies, this platform integrates CrestOptics’ spinning disk confocal technology with Tomocube’s latest innovation...
Spin-out ChromaTwist has won a prestigious Innovate UK Smart grant to co-fund a £0.5m project. The funding from Innovate UK, the UK’s innovation agency, covers 70% of the cost of a project that will take ChromaTwist’s novel dyes to the next level in terms of enhanced brightness and staining indices, to make cells and cellular structures stand out more clearly during bio-imaging...
Linkam Scientific Instruments has announced new updates to its specialist CMS196 cryo-stage. The CMS196V4 supports cryo-correlative light and electron microscopy (cryo-CLEM) and allows researchers to investigate samples at cryogenic temperatures down to < -195 °C. The latest updates to the CMS196V4 stage include an improved user interface featuring a touch-panel and joystick, alongside an encoded and motorised XY stage which allows high-precision automated mapping of sample grid...
These products allow direct coupling of Nikon’s LED light source to stereo microscopes without the need for fiber optics. Stereo microscopes are suitable for observing large samples. To observe detailed internal structures, a technique called "fluorescent observation" is used, in which features of interest are stained with fluorescent proteins such as GFP or fluorescent dyes to highlight them against a dark background. Epi-fluorescence attachments are needed to pass light...
In the development and analysis of advanced materials, the interplay between surface chemistry and structural properties is essential for understanding material behaviour. However, since several different methods — such as scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) — may need to be used, ensuring that data is obtained from the same regions of interest is vital. Here, Christopher Deeks, Channel Manager XPS at Thermo Fisher Scientific, explores how implementing a Correlative Imaging and Surface...
Leica Microsystems, a leader in microscopy and scientific instrumentation and advanced imaging solutions, has announced that it has acquired ATTO-TEC, a leading specialty supplier of fluorescent dyes and reagents. The addition of dyes and reagents for sample preparation complements the renowned Leica portfolio of microscopy imaging platforms and advanced AI-based analysis software...
Agilent Technologies Inc. has announced the Agilent IDP-35 and IDP-45 dry scroll pumps, designed to provide quiet, efficient, oil-free, and worry-free vacuum solutions for applications requiring higher pumping capacity. Consistent with the high standards of all Agilent IDP scroll pumps, the new IDP-35 and IDP-45 pumps offer several key benefits to customers. These pumps are ideal for applications needing higher pumping capacity without the drawbacks of oil-sealed pumps...
Hitachi High-Tech Europe has introduced the SU3800SE and SU3900SE Schottky field emission scanning electron microscopes (SEMs) to offer fully automatic optical alignment, allowing high-resolution results to be achieved quickly and easily by any user. The large sample handling and variable pressure operation means they can accommodate a wide range of sample types, and the powerful automation tools enable easy acquisition of large datasets...
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Invitrogen™ EVOS™ S1000 Spatial Imaging System. This advanced system addresses the limitations of current fluorescent microscopy technologies by enabling researchers to generate a multiplexed high-quality image for multiple samples within several hours, thereby lowering the barrier to entry into spatial tissue proteomics...
Say hello to our newest, fastest and most intuitive imaging solution - providing deeper insights for every lab. Empower your team to quickly obtain high-definition images and robust data from a wide range of 2D and 3D cell assays - and upgrade the system as your research needs evolve.The ImageXpress HCS.ai system features a modular design and a wide array of configuration options, allowing for customization to meet your current needs and on-site upgrades as your requirements evolve - eliminating the need to purchase a new system...
Aston Institute for Membrane Excellence (AIME) has received a £500,000 grant from the Wolfson Foundation to purchase an ultrafast confocal spinning disc microscope. This instrument will accelerate AIME research, led by Professor Roslyn Bill, into treatments for dementia and other forms of cognitive decline. An ultrafast spinning disc confocal microscope enables faster, higher-resolution images of biological processes than is currently possible at AIME...
In materials science, achieving precise and repeatable scanning electron microscopy (SEM) analysis requires pristine sample surfaces. However, handling and preparation methods frequently degrade the sample’s condition, making it challenging to observe the material's essential features. Here, Britta Siefer, SEM expert at Thermo Fisher Scientific, explains how a reliable workflow can preserve sample integrity for quality analysis...
Leica Biosystems, a global leader in anatomic and digital pathology solutions; and Indica Labs, a global leader in artificial intelligence (AI)-powered digital pathology software, have announced that Leica Biosystems has agreed to make a significant strategic investment in Indica Labs. This partnership has the potential to accelerate AI-enabled companion diagnostics (CDx) and support discoveries and treatments based on discrete or complex biomarker expression profiles which are not discernable by the human eye.
Physicists are getting closer to controlling single-molecule chemical reactions – could this shape the future of pharmaceutical research? A new study, published in the prestigious journal Nature Communications, set out to demonstrate for the first time that competing chemical reaction outcomes can be influenced by using the atomic resolution of a scanning tunnelling microscope (STM).
ZEISS partners with Mindpeak, a pioneer in AI-powered pathology solutions, to develop an integrated Multiplex Immunofluorescence (mIF) solution that serves pathologists across research, diagnostics, and clinical applications. Mindpeak’s expertise in AI-based image analysis of pathological tissues, particularly through its established algorithms for clinical routine applications, complements ZEISS's advanced instruments and software for research applications of mIF...
Conducting quality control analysis in-house can offer time-saving benefits and help to control costs and protect confidential information. However, for companies that are not experienced in selecting an appropriate microscope, outsourcing SEM capabilities to a university or laboratory can be a tempting option. Here, Robbie O’Connell, Sales Account Manager (Electron Microscopy) at SEM specialist Thermo Fisher Scientific, offers advice on what to look for when purchasing an SEM for quality control purposes...
Queensgate and the United Kingdom's National Metrology Institute have revealed their latest breakthrough at Euspen’s Special Interest Conference: Precision Motion Systems and Control in November. The development is a novel control system for a two-axis flexure stage with a 100 µm x 100 µm scanning range that enables high-speed atomic force microscopy (HS-AFM) over large areas. The result is an HS-AFM system capable of imaging large areas with molecular-level resolution...
Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers have captured a real-time molecular movie to show how two essential cellular processes – transcription and translation – interact with each other in bacteria...
Bruker Corporation announces the launch of the Dimension Nexus™ atomic force microscope (AFM). Dimension Nexus is the newest addition to the industry‑leading Dimension® AFM product line, which has had more than 4600 systems installed around the world. With the latest‑generation NanoScope® 6 controller, this new small‑footprint AFM delivers wider access to Bruker’s exclusive PeakForce Tapping® technology and over 50 AFM modes...
Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists seeking to harness the utility of the GFP (green fluorescent protein) tag. GFP is a common fusion protein tag that enables protein expression to be monitored, quantified, and localized within the complex environment of the cell...
TESCAN Group has reopened its existing Tempe R&D facility, adding a laboratory showcasing TESCAN’s latest electron microscopy technologies. The lab features the TESCAN TENSOR STEM and the newly launched Solaris 2 FIB-SEM, offering customers hands-on demonstrations and specialized support in sectors such as Materials Science and Semiconductor R&D, Failure Analysis and Process Monitoring...
Evident recently announced the release of its IXplore™ IX85 automated inverted microscope system. With an industry-leading 26.5mm field number (FN), combined with new advanced imaging tools that ensure clear, accurate results, this new system empowers researchers to capture more data and uncover new insights faster than ever before. It also delivers an unmatched level of customizability, allowing users to design or build an intelligent, high-performance imaging platform that meets their specific goals...
CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy, and Tomocube, a leader in holotomography (HT) technology, today announced a strategic collaboration to provide a next-generation multimodal imaging platform, the HT-X1™ Plus. By combining the expertise of both companies, this platform integrates CrestOptics’ spinning disk confocal technology with Tomocube’s latest innovation...
Spin-out ChromaTwist has won a prestigious Innovate UK Smart grant to co-fund a £0.5m project. The funding from Innovate UK, the UK’s innovation agency, covers 70% of the cost of a project that will take ChromaTwist’s novel dyes to the next level in terms of enhanced brightness and staining indices, to make cells and cellular structures stand out more clearly during bio-imaging...
Linkam Scientific Instruments has announced new updates to its specialist CMS196 cryo-stage. The CMS196V4 supports cryo-correlative light and electron microscopy (cryo-CLEM) and allows researchers to investigate samples at cryogenic temperatures down to < -195 °C. The latest updates to the CMS196V4 stage include an improved user interface featuring a touch-panel and joystick, alongside an encoded and motorised XY stage which allows high-precision automated mapping of sample grid...
These products allow direct coupling of Nikon’s LED light source to stereo microscopes without the need for fiber optics. Stereo microscopes are suitable for observing large samples. To observe detailed internal structures, a technique called "fluorescent observation" is used, in which features of interest are stained with fluorescent proteins such as GFP or fluorescent dyes to highlight them against a dark background. Epi-fluorescence attachments are needed to pass light...