Recent Articles in General Laboratory Articles and Application Notes
Back to basics with Malvern Instruments particle characterization white paperJun 1, 2012From a starting point of ‘what is a particle?', Malvern Instruments' new ‘A basic guide to particle characterization' white paper takes the reader through descriptions of a range of particle properties and then goes on to introduce a variety of different particle characterization techniques. Designed both as a primer for those new to particle characterization and as a refresher for the more experienced...
Read MoreMalvernMay 29, 2012A performance-defining parameter in products from paint and coatings to personal care
A new white paper from Malvern Instruments is aimed at helping product developers and formulators get to grips with the measurement of yield stress. Yield stress is a rheological parameter that is industrially important in defining the performance of food, paint, personal care and many other products. In order to obtain relevant, robust and reproducible yield stress data for a particular material, it is essential to make an assessment of both the test type, and the measurement protocol used to perform the test. The white paper ‘Understanding yield stress measurements' provides a valuable introduction to the topic... Read MoreMalvern team presents May 22, 2012Malvern Instruments light scattering specialists Dr Ana Morfesis and Dr Ulf Nobbmann, will present a poster on ‘Nanoparticle characterization by light scattering' as part of the 86th ACS Colloid and Surface Science Symposium being held at the University of Baltimore in Maryland, USA, June 10-13, 2012. Their poster will be displayed from 5.30 until 7.30 pm on Monday June 11 in a session held in the exhibition area, where delegates will also be able to visit the Malvern booth to find out more about the company's full range of systems for nanoparticle characterization, including the market leading Zetasizer Nano.
Read MoreNew Applications Resource from BMG LABTECHMay 15, 2012A perfectly engineered microplate reader is only part of the solution. Knowing how to effectively perform all of the leading applications on that instrument is the final piece of the puzzle. This is why BMG LABTECH has created an application notes binder, which combines all of the current application notes into one resource. The application notes detailed in our Application Notes Binder were all performed on BMG LABTECH's wide range of microplate readers and they outline a variety of experiments...
Read MoreNew Malvern download with detailed Zetasizer specifications helps users match system with applicationMay 9, 2012In line with a policy of continuous improvement, Malvern Instruments has reviewed, verified and published updated specifications for the Zetasizer series of dynamic light scattering (DLS) particle characterization systems, all fully backed by measurements on real samples. Full updated specification details are available online...
Read MoreMetrohm publishes new Application Notes (ANs) about photometric titrationMay 2, 2012Accompanying the introduction of the new Optrode photometric sensor, Metrohm presents a range of titrimetric applications using the advantages of photometric detection of the equivalence point. The new applications cover a number of industries including the pharmaceutical industry, the petrochemical industry, and water analysis. The new ANs are available for free from the homepage of Metrohm International Headquarters...
Read MorePermanganate index: fully automatic determination according to DIN EN ISO 8467 (DIN 38409-5)Apr 17, 2012Metrohm presents a method for completely automated determination of the permanganate index according to DIN EN ISO 8467 (DIN 38409-5). The new method not only saves time, but is robust and, because of the tiamoTM titration software, very easy to use. The permanganate index is used to evaluate the quality of different types of water, e.g. drinking water, mineral water, spring water, and table water. It is determined in accordance with DIN EN ISO 8467 (DIN 38409-5)...
Read MoreReliable method for characterising PFC'sApr 16, 2012Exeter Analytical has developed a reliable analytical method for accurately determining the percentage Carbon (C), Hydrogen (H) and Nitrogen (N) content of polyfluorinated compounds (PFCs). Polyfluorinated compounds are extremely thermally and chemically stable and have soil, water and fat-repellent properties. They are nearly non-biodegradable and accumulate in the environment and the food chain...
Read MoreGas Analyzers Meet Stringent Requirements of Respiration CalorimetersApr 13, 2012MEI Research is an engineering firm based in St. Louis Park, MN, that develops technologies to support research in nutrition and weight management.One of MEI's goals is to improve the design and construction of whole-body respiration calorimeters. These instrumented systems calculate energy expenditure by precisely measuring the amount of oxygen that the body converts by metabolism to carbon dioxide during periods from minutes up to several days. Calorimeters comprise sealed living areas, atmosphere controls and gas analyzers. Because the living areas contain thousands of times more air than respiratory volume the accuracy of the analytical systems that measure carbon dioxide (CO2) and oxygen (O2) concentrations is critical to overall performance... Read MoreCheese aromas pinpointed by innovative techniqueApr 5, 2012Food scientists working in the dairy industry are set to benefit from the development of a powerful new technique for analysing the aroma profile of cheese. The innovative method, which uses technology developed by Markes International to analyse vapours emitted by a sample, will enable analysts to identify the specific chemical compounds released by different cheeses, even when they are present at trace levels and have low odour thresholds...
Read MoreUnlocking the potential of Stem Cells in Neuroscience ResearchJan 25, 2012AMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...
Read MoreHORIBA Medical in partnership with Spire Healthcare undertake haematology analyser comparison studyNov 30, 2011Following its debut presentation at IBMS Congress 2011, the results poster of the Spire Healthcare-commissioned granulocyte and neutrophil count comparison study of HORIBA Medical's ABX Micros ES 60 and three other methodologies is now available to view at the HORIBA Medical-UK website. The study shows that the granulocyte count of the ABX Micros ES 60 can be considered a neutrophil count in the absence of flags, making it a suitable instrument for all Point-of-Care (POC) settings...
Read MoreNew Article from Sartorius - AriumR pro UV Ultrapure Water for ICP-MSNov 23, 2011Sartorius Stedim Biotech, a leading provider of cutting-edge equipment and services for the development, quality assurance and production processes of the biopharmaceutical industry, released an article exploring the importance of using pure water of a high analytic grade quality when conducting inductively coupled plasma mass spectrometry (ICP-MS). The objective of the analytical test series described in the article is to ensure that the ultrapure water generated by the arium® pro UV water systems has a high purity level (in this case free of metal elements respectively metal elements not detectable) and can be used without any problems for trace analysis of elements performed with ICP-MS devices...
Read MoreNew white paper outlines solution for reliable multi-way fluidic connectionsNov 22, 2011Dolomite, a world leader in the design and manufacture of microfluidic devices, has launched a new white paper addressing the challenges faced by engineers and scientists when working with microfluidic connections. Traditional solutions for tube-to-tube and tube-to-chip connections, which consist of a selection of unions, take up a lot of space and involve a time consuming set-up and problem of sealing when using multiple unions. Furthermore they only allow the connection of one fluid tube at a time...
Read MoreNew Application Note from BMG LABTECHNov 18, 2011The BlueScreen HC assay from Gentronix utilizes a luminescence-based reporter system to measure genotoxicity. The assay generates positive results e.g for direct-acting mutagens and clastogens and correct negative results for non-carcinogens. In addition, reduced cell proliferation, a measure of cytotoxicity, is assessed, too. Using the FLUOstar Omega microplate reader from BMG LABTECH the BlueScreen HC assay has been shown to be fast, accurate and reproducible...
Read MoreInfrared Thermography Helps Improve Comfort of AthletesNov 14, 2011FLIR Advanced Thermal Solutions has announced a new application story that describes how leading sportswear manufacturer - Adidas has used infrared thermography to help develop a new generation of sports shoes featuring ventilated ClimaCool2™ technology...
Read MoreNew data demonstrate the value of Zetasizer Oct 26, 2011Two new, free to download, technical notes from Malvern Instruments describe the function and benefits of using the Zetasizer µV as a detector for size exclusion chromatography (SEC), focusing on its suitability for protein characterization. Capable of dynamic (DLS) and static light scattering (SLS) detection, the compact Zetasizer μV simultaneously measures absolute size and molecular weight, maximizing the information produced by each measurement to increase experimental productivity. The OmniFACE connection interface from Malvern Instruments (Malvern, UK) enables the...
Read MoreNew Application Note - DNA measurements in low volume samples, microplates and cuvettes on the SPECTROstar NanoOct 18, 2011The SPECTROstar Nano offers different possibilities to measure DNA in UV absorbance mode. If there is enough DNA material available and only a few samples that should be measured, cuvette measurements can be performed. For higher throughput a microplate should be used. If sample volume is very limited, then the LVis Plate is recommended as it offers a great linear range, a high sensitivity and only 2 µl of sample is needed...
Read MoreSpinnovation points stem cell culture in the right directionOct 7, 2011Spinnovation, the NMR profiling experts, have produced a detailed case study examining the utility of NMR profiling methodology to monitor and optimise stem cell culture media, for the production of biologics and cells for therapeutic purpose...
Read MoreNew Application Note - Growth of Campylobacter using BMG LABTECHSep 23, 2011Growth of the fastidious microorganism Campylobacter jejuni was monitored using a FLUOstar Omega microplate reader equipped with the Atmospheric Control Unit (ACU). With the ACU it was possible to independently control the oxygen to 7 % and the carbon dioxide to 10 %. Growth curves obtained in 96-well microplates were comparable to conventional growth measurements where samples are taken and measured in cuvettes...
Read MoreNew Application Note - Miniaturised Platelet Aggregation Assays using the NOVOstar Microplate ReaderSep 22, 2011Platelet aggregation is a "gold standard" assay of platelet function in the research and clinical laboratory settings which is conventionally measured with aggregometers requiring large volumes of platelet suspensions and only in low throughput format. With the NOVOstar microplate reader from BMG LABTECH we present an alternative optical method to measure platelet aggregation using small volumes in 96-well format...
Read MoreLandmark publication reports potential of exosomes as biomarkers for early disease detection using NanoSightSep 13, 2011NanoSight, leading manufacturers of unique nanoparticle characterization technology, reports the new publication in one of the most cited peer reviewed journals in nanoscience and nanotechnology, NanoMedicine. It has been written by a group of researchers from the Nuffield Department of Obstetrics & Gynaecology, Oxford University...
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From a starting point of ‘what is a particle?', Malvern Instruments' new ‘A basic guide to particle characterization' white paper takes the reader through descriptions of a range of particle properties and then goes on to introduce a variety of different particle characterization techniques. Designed both as a primer for those new to particle characterization and as a refresher for the more experienced...
A new white paper from Malvern Instruments is aimed at helping product developers and formulators get to grips with the measurement of yield stress. Yield stress is a rheological parameter that is industrially important in defining the performance of food, paint, personal care and many other products. In order to obtain relevant, robust and reproducible yield stress data for a particular material, it is essential to make an assessment of both the test type, and the measurement protocol used to perform the test. The white paper ‘Understanding yield stress measurements' provides a valuable introduction to the topic...
Malvern Instruments light scattering specialists Dr Ana Morfesis and Dr Ulf Nobbmann, will present a poster on ‘Nanoparticle characterization by light scattering' as part of the 86th ACS Colloid and Surface Science Symposium being held at the University of Baltimore in Maryland, USA, June 10-13, 2012. Their poster will be displayed from 5.30 until 7.30 pm on Monday June 11 in a session held in the exhibition area, where delegates will also be able to visit the Malvern booth to find out more about the company's full range of systems for nanoparticle characterization, including the market leading Zetasizer Nano.
A perfectly engineered microplate reader is only part of the solution. Knowing how to effectively perform all of the leading applications on that instrument is the final piece of the puzzle. This is why BMG LABTECH has created an application notes binder, which combines all of the current application notes into one resource. The application notes detailed in our Application Notes Binder were all performed on BMG LABTECH's wide range of microplate readers and they outline a variety of experiments...
In line with a policy of continuous improvement, Malvern Instruments has reviewed, verified and published updated specifications for the Zetasizer series of dynamic light scattering (DLS) particle characterization systems, all fully backed by measurements on real samples. Full updated specification details are available online...
Accompanying the introduction of the new Optrode photometric sensor, Metrohm presents a range of titrimetric applications using the advantages of photometric detection of the equivalence point. The new applications cover a number of industries including the pharmaceutical industry, the petrochemical industry, and water analysis. The new ANs are available for free from the homepage of Metrohm International Headquarters...
Metrohm presents a method for completely automated determination of the permanganate index according to DIN EN ISO 8467 (DIN 38409-5). The new method not only saves time, but is robust and, because of the tiamoTM titration software, very easy to use. The permanganate index is used to evaluate the quality of different types of water, e.g. drinking water, mineral water, spring water, and table water. It is determined in accordance with DIN EN ISO 8467 (DIN 38409-5)...
Exeter Analytical has developed a reliable analytical method for accurately determining the percentage Carbon (C), Hydrogen (H) and Nitrogen (N) content of polyfluorinated compounds (PFCs). Polyfluorinated compounds are extremely thermally and chemically stable and have soil, water and fat-repellent properties. They are nearly non-biodegradable and accumulate in the environment and the food chain...
MEI Research is an engineering firm based in St. Louis Park, MN, that develops technologies to support research in nutrition and weight management. One of MEI's goals is to improve the design and construction of whole-body respiration calorimeters. These instrumented systems calculate energy expenditure by precisely measuring the amount of oxygen that the body converts by metabolism to carbon dioxide during periods from minutes up to several days. Calorimeters comprise sealed living areas, atmosphere controls and gas analyzers. Because the living areas contain thousands of times more air than respiratory volume the accuracy of the analytical systems that measure carbon dioxide (CO2) and oxygen (O2) concentrations is critical to overall performance...
Food scientists working in the dairy industry are set to benefit from the development of a powerful new technique for analysing the aroma profile of cheese. The innovative method, which uses technology developed by Markes International to analyse vapours emitted by a sample, will enable analysts to identify the specific chemical compounds released by different cheeses, even when they are present at trace levels and have low odour thresholds...
AMSBIO has written an informative technical article to enable neuroscience researchers to learn more about a new method to control and direct differentiation of physiologically relevant neural cell types using stem cell qualified reagents. Stem cells have revolutionized our approaches to and understanding of neuroscience. The key to research success is the ability to control and direct differentiation into physiologically relevant neural cell types...
Following its debut presentation at IBMS Congress 2011, the results poster of the Spire Healthcare-commissioned granulocyte and neutrophil count comparison study of HORIBA Medical's ABX Micros ES 60 and three other methodologies is now available to view at the HORIBA Medical-UK website. The study shows that the granulocyte count of the ABX Micros ES 60 can be considered a neutrophil count in the absence of flags, making it a suitable instrument for all Point-of-Care (POC) settings...
Sartorius Stedim Biotech, a leading provider of cutting-edge equipment and services for the development, quality assurance and production processes of the biopharmaceutical industry, released an article exploring the importance of using pure water of a high analytic grade quality when conducting inductively coupled plasma mass spectrometry (ICP-MS). The objective of the analytical test series described in the article is to ensure that the ultrapure water generated by the arium® pro UV water systems has a high purity level (in this case free of metal elements respectively metal elements not detectable) and can be used without any problems for trace analysis of elements performed with ICP-MS devices...
Dolomite, a world leader in the design and manufacture of microfluidic devices, has launched a new white paper addressing the challenges faced by engineers and scientists when working with microfluidic connections. Traditional solutions for tube-to-tube and tube-to-chip connections, which consist of a selection of unions, take up a lot of space and involve a time consuming set-up and problem of sealing when using multiple unions. Furthermore they only allow the connection of one fluid tube at a time...
The BlueScreen HC assay from Gentronix utilizes a luminescence-based reporter system to measure genotoxicity. The assay generates positive results e.g for direct-acting mutagens and clastogens and correct negative results for non-carcinogens. In addition, reduced cell proliferation, a measure of cytotoxicity, is assessed, too. Using the FLUOstar Omega microplate reader from BMG LABTECH the BlueScreen HC assay has been shown to be fast, accurate and reproducible...
FLIR Advanced Thermal Solutions has announced a new application story that describes how leading sportswear manufacturer - Adidas has used infrared thermography to help develop a new generation of sports shoes featuring ventilated ClimaCool2™ technology...
Two new, free to download, technical notes from Malvern Instruments describe the function and benefits of using the Zetasizer µV as a detector for size exclusion chromatography (SEC), focusing on its suitability for protein characterization. Capable of dynamic (DLS) and static light scattering (SLS) detection, the compact Zetasizer μV simultaneously measures absolute size and molecular weight, maximizing the information produced by each measurement to increase experimental productivity. The OmniFACE connection interface from Malvern Instruments (Malvern, UK) enables the...
The SPECTROstar Nano offers different possibilities to measure DNA in UV absorbance mode. If there is enough DNA material available and only a few samples that should be measured, cuvette measurements can be performed. For higher throughput a microplate should be used. If sample volume is very limited, then the LVis Plate is recommended as it offers a great linear range, a high sensitivity and only 2 µl of sample is needed...
Spinnovation, the NMR profiling experts, have produced a detailed case study examining the utility of NMR profiling methodology to monitor and optimise stem cell culture media, for the production of biologics and cells for therapeutic purpose...
Growth of the fastidious microorganism Campylobacter jejuni was monitored using a FLUOstar Omega microplate reader equipped with the Atmospheric Control Unit (ACU). With the ACU it was possible to independently control the oxygen to 7 % and the carbon dioxide to 10 %. Growth curves obtained in 96-well microplates were comparable to conventional growth measurements where samples are taken and measured in cuvettes...
Platelet aggregation is a "gold standard" assay of platelet function in the research and clinical laboratory settings which is conventionally measured with aggregometers requiring large volumes of platelet suspensions and only in low throughput format. With the NOVOstar microplate reader from BMG LABTECH we present an alternative optical method to measure platelet aggregation using small volumes in 96-well format...
NanoSight, leading manufacturers of unique nanoparticle characterization technology, reports the new publication in one of the most cited peer reviewed journals in nanoscience and nanotechnology, NanoMedicine. It has been written by a group of researchers from the Nuffield Department of Obstetrics & Gynaecology, Oxford University...