Novel method of image analysis reveals how cancer cells manipulate their size to resist treatment. Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments...
Computational chemistry, a branch of chemistry that applies computer simulation to assist in solving chemical problems, is a heated topic in the modern scientific community. Possessing a powerful team of experts in chemistry, biology, mathematics, crystallography, and pharmacology, Alfa Chemistry focuses on combining the power of computational chemistry with a variety of research focuses on supporting Computer Aided Drug Design...
Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products,has announced the launch of the CFX Opus Deepwell Dx Real-Time PCR System, a real-time PCR system listed with the U.S. Food and Drug Administration (FDA) for in vitro diagnostic (IVD) testing, and developed in accordance with the European Union’s regulations for in vitro diagnostic medical devices (EU 2017/746)...
Wastewater testing labs can now scale up their infectious disease surveillance using two reliable technologies in a single kit. The new system released by Promega Corporation pairs the company’s Maxwell HT chemistry® with Ceres Nanosciences’ Nanotrap® particles, an established technology for capturing and concentrating low-abundance analytes such as viral particles. Together, these technologies empower labs to purify pathogen nucleic acids from wastewater samples in high-throughput workflows...
Agilent Technologies has announced it is investing approximately $725 million to double manufacturing capacity of therapeutic nucleic acids in response to rapid growth of the $1 billion market and strong demand for the company’s high-quality active pharmaceutical ingredients (API).Therapeutic nucleic acids, also called therapeutic oligonucleotides or oligos, are short DNA and RNA molecules that serve as the API for drugs targeting a growing number of diseases...
Azenta, Inc. has announced that it has acquired Ziath, Ltd. and its subsidiaries ("Ziath"). Based in Cambridge, UK, Ziath is a leading provider of 2D barcode readers for life sciences applications. Founded in 2005, Ziath's innovative 2D barcode readers are a key component of the laboratory automation workflow serving pharmaceutical, biotech and academic customers worldwide...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast series on Wednesday, February 15, with See How LIMS is Making a Splash in the Water/Wastewater Industry. This webcast will provide an update on some of the leading challenges water, wastewater, and environmental laboratories are facing today and focus on the ways in which some of the latest advances in laboratory automation and LIMS are addressing these challenges...
INTEGRA Biosciences has expanded its range of products to include 8 row and 12 column automation friendly reagent reservoirs, offering a greater variety of reservoir dimensions to suit the increasing diverse applications of automated workstations. Laboratory automation is increasingly important, driving a need for reagent reservoirs that are compatible with industry-standard liquid handling platforms...
Chemists from the Chianese Group at Colgate University (NY, USA) have shared kinetic data obtained using the Asynt Multicell 10-position high pressure laboratory reactor in their recent paper, “The Key Role of the Latent N0H Group in Milstein’s Catalyst for Ester Hydrogenation”. Their characterisation of the mechanisms of Milstein’s catalysts has enabled greater understanding of the reactivity of these catalysts in ester hydrogenation...
For high-resolution imaging, immersion media between the sample and objective is required. This can be a challenge for some experiments using water as immersion media. One application of immersion media might not be sufficient as the sample moves to different locations and water evaporates over long periods of time. Manual addition risks loss of data points, microscope damage, and is tedious and inefficient...
Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published an update to its guide on “Environmental Monitoring Processes and Validation”, incorporating specific detail on the new version of EU GMP Annex 1. This aims to help sterile medicinal product manufacturers with reviewing and improving their Environmental Monitoring (EM) programs in preparation for compliance with the revised guidelines by August 2023...
Analytik Jena's thermal cyclers are known for their high-performance and excellent temperature management. To make them even easier and more convenient to operate and monitor, the company has launched new thermal cycler management software. Efficiency pressure and documentation obligations – the challenges in everyday life science laboratories continue to increase. With its new thermal cycler software "Biometra TSuite", Analytik Jena is addressing precisely this issue...
Automata, a leading robotics and automation company powering life sciences labs, has announced it is partnering with bit.bio, to automate a key aspect of the manufacturing process of their iPSC (induced pluripotent stem cell)-derived human cell products. bit.bio’s precision cellular reprogramming technology opti-ox is ideally suited for automation because it enables unprecedented consistency and scalability for the manufacture of human cells from iPSCs...
Agilent Technologies, Inc. has announced a partnership with Akoya Biosciences, Inc., The Spatial Biology Company®, to develop multiplex-immunohistochemistry diagnostic solutions for tissue analysis and to commercialize workflow solutions for multiplex assays in the clinical research market. Integrating Agilent’s Dako Omnis (autostaining instrument) and Akoya’s PhenoImager® HT (imaging platform) for multiplex chromogenic immunohistochemistry (mIHC) and immunofluorescent (mIF) assays...
New Virtual Powder Flow Course happening in February 2023 focusing on the properties of powders! Understanding the flow of powders is essential in many industrial applications. Anyone working with powdered materials has once experienced processability problems like a lack of flowability, heavy sticking on pipes and machine surfaces, or variability in dosage among many other examples...
Global warming is a challenge for humanity - Sharm el-Sheikh has just reminded us of this again. But in addition to abstract global issues of the UN, small, personal steps can also help. Discussions about sustainability are primarily about energy consumption. Laboratory equipment is no exception. Even the most environmentally friendly and energy efficient ultra-low temperature freezers still require a significant amount of energy to maintain extremely low temperatures of -80 °C 24 hours a day, 7 days a week, for years...
Thermo Fisher Scientific, the world leader in serving science, has announced the launch of its CE-IVD marked Applied Biosystems TaqPath Seq HIV-1 Genotyping Kit, a Sanger sequencing-based assay that examines positive samples of human immunodeficiency virus (HIV) to identify genetic variants that may resist common antiretroviral therapeutics...
Nanopositioning expert, Queensgate, has announced the launch of the Nano Scan OP800 piezo objective scanner.?Its unique mechanical design together with integral capacitive feedback sensors offer users market-leading positioning accuracy, while its stiff construction allows the standard selectable tuning pre-sets to support a range of objectives from 150?g to 500?g. This makes it highly versatile for use in a wide range of applications in life sciences and industry...
Most single-cell technologies today require cells to be manipulated one way or another, either by being frozen, fixed, or physically squeezed into microchannels or nanowells. Those requirements compromise the transcriptome with the cell altering gene expression in response and drifting further away from the physiological conditions. But novel solutions such as Asteria™ now enable fresh cells to be processed to preserve their transcriptome and thus the accuracy of the single-cell data...
Being committed to continued advances in improving human health, SCHOTT has opened a new facility in Phoenix, Arizona, to expand the development and manufacturing of diagnostics and life science consumables. Launching the first fully integrated microfluidic foundry in the United States validates SCHOTT’s global growth plan and increases production capabilities to help get these products to market faster and more efficiently...
Uniqsis reports that demand for its Flow-UV inline UV-Visible spectrophotometer for biological, biotech, drug discovery and industrial applications grew to record levels during 2022. Compact in design, the Flow-UV from Uniqsis sets a benchmark for real time monitoring of continuous flow and batch applications. Unlike many UV-visible spectrophotometers the high-resolution Flow-UV CCD array detector does not require calibration or routine servicing...
Calibre Scientific is pleased to announce the acquisition of Dynalab Corp. (the “Company”), a Rochester, NY based distributor and manufacturer of laboratory plastics, consumables, equipment, supplies and custom fabricated products serving the scientific, industrial, agricultural, water, pharma and educational markets in the United States. Dynalab marks Calibre Scientific’s debut into the United States distribution market...