UK headquartered iPSC disease modelling company DefiniGEN has identified iPSC-derived intestinal organoids that could be used to help structure in vitro studies of the biology of SARS-CoV2 infection across cohorts of multiple patients. While SARS-CoV-2 primarily targets the respiratory system, studies have shown that it also infects and multiplies within the intestinal epithelium. IPSC-derived organoids exhibit characteristics that closely mimic the in vivo intestinal epithelium, making them a valuable surrogate model for studying the virus....
Are you required to analyse very small sample amounts? Or do you need to analyse very low concentrations of antibodies in different kinds of matrices? By using of microLC-MS/MS, only a very small amount of valuable samples, e.g. solutions prepared for patient application (usually a dilution of the dosage form), is required to identify and quantify. In addition, microLC-MS/MS can also be used to monitor residues on surfaces or materials in hospitals, pharmacies or laboratories that prepare solutions for patient application....
In this new 10-page Technology Note, learn how different image processing methods have the potential to make widefield microscope systems more powerful and versatile. Understand each methods limitations and pitfalls, as well as suitability for your specific applications. For decades, fluorescence microscopy has been an invaluable tool in life sciences research, with new variations and implementations emerging almost every year....
Analytik reports how the renowned Quadram Institute (Norwich, UK) has invested in a ZetaView Nanoparticle Tracking Analyser to help them develop a new approach for vaccine delivery based on engineering the natural ability of resident gut bacteria to generate nanoparticle sized Outer Membrane Vesicles (OMVs). In combination with the latest developments in recombinant protein production established at the University of Kent, Department of Synthetic Biology and Bioinformatics, researchers at the Quadram Institute have identified key antigen targets within the COVID-19 virus...
Digital Science, a leading technology company serving emergent needs across the research sector, has released a report highlighting the global research landscape trends and cultural changes in response to the COVID-19 pandemic. The report How COVID-19 is Changing Research Culture analyses publication trends, regional focal points of research, collaboration patterns, and top institutional producers of research in COVID-19....
New UK Biobank research, led by the University of Glasgow and published in BMC Medicine, has found that black and south Asian ethnic groups have a higher risk of testing positive with SARS-CoV-2, the virus which causes COVID-19. These groups were also at a higher risk of testing positive while attending hospital, suggesting they were also at greater risk of severe disease from the virus...
As a leading British autoclave manufacturer, Priorclave is delighted to announce that it has gained approval by the SFDA- Saudi Food & Drug Authority for its entire range of range of research grade laboratory autoclaves. This is an important development and will enable the company to further expand its business in the region. Priorclave has developed and manufactures more than 60 standard laboratory models at its UK production facility....
At Lab Innovations, the UK’s largest trade exhibition for the laboratory industry, professionals, scientists, researchers and more will come together and do business for the first time in 2020. On 4 & 5 November 2020, at the NEC, Birmingham, the show will open its doors to a visitors and exhibitors with a bigger floor space than ever before. Despite the unfortunate start of the year, where trade shows throughout the country have had to be cancelled or postponed, Lab Innovations is scheduled to drive the business of science once again in 2020...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new and improved Matrix Gemini Pharmaceutical/Manufacturing LIMS to meet the changing needs of the pharmaceutical, manufacturing and regulated industries. Designed specifically for pharmaceutical and other regulated and non-regulated manufacturing industries the solution...
Avacta and Adeptrix will collaborate to develop and manufacture an Affimer-based BAMS coronavirus antigen test that will provide clinicians with a significant expansion of the available testing capacity for COVID-19 infection in hospitals. Adeptrix’s novel BAMS platform combines enrichment of the sample to improve sensitivity with the power of mass-spectrometry to improve specificity...
To assist labs involved with the essential RT-PCR assay part of the “test, trace and isolate” strategy for dealing with the SARS-CoV-2 virus pandemic – Ziath has introduced two optimized packages for reliable tracking of patient samples submitted for Coronavirus (COVID-19) testing. For large-scale, high-density Coronavirus (COVID-19) testing labs...
21st century laboratory equipment needs to be affordable, and offer the highest levels of safety. The Guardian 7000 and 5000 Series Hotplate Stirrers assure safe operation and deliver advanced performance with OHAUS SMART technology for users looking for durable hotplate stirrers with industry-leading safety features for advanced applications in laboratory, industrial and education settings.
Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, has announced the launch of a range of anti-certolizumab pegol inhibitory antibodies to support the development of assays for therapeutic drug monitoring of tumor necrosis factor (TNF) alpha inhibitors. By extending its offering to include anti-certolizumab pegol antibodies...
Alfa Chemistry Testing Lab, a professional testing and analysis organization, have released nano-products safety evaluation services for companies and agencies that are engaged with the development and application of nano-products. Nanomaterials exhibit unique physical and chemical properties in contrast with engineered materials....
From sourdough starters to biotechnological bugs, micro-organisms make the products society wants and needs. The new European Green Deal is dependent on engineered microbes to make biochemicals to replace oil and synthetic chemicals as building blocks for consumer goods. Microbes can be repurposed to make useful products but one limitation is that many microbes are not able...
The LAUDA Varioshake product line comprises ten shakers in three sizes with five different shaking motions, as well as three shaking incubators in three sizes with a circular motion. Like the new LAUDA Hydro water baths, the Varioshake shakers feature “GFL Technology” and represent the many years of experience and outstanding quality of premium manufacturer GFL Gesellschaft für Labortechnik ...
Oxford Immunotec releases the T-SPOT® Discovery™ SARS-CoV-2 kit for research into measuring the T cell immune response to SARS-CoV-2, which may offer new insights into immunity to COVID-19. This kit is for research use only and launched under the T-SPOT Discovery brand. This research kit could make a significant contribution towards development of a new tool to manage the COVID-19 pandemic...
Indica Labs, a leading provider of computational pathology software, and Octo, a premiere information technology systems provider to the U.S. Federal Government, are pleased to announce the online COVID Digital Pathology Repository (COVID-DPR), a virtual collection of high resolution microscopic COVID-related human tissue images hosted at the National Institutes of Health....
A new generation, high resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterization and small-molecule scientists the analytical performance required for research and high-throughput analyses. The new system will help drive discovery and identification with increased accuracy for confident scale-up while operational simplicity and speed streamline time to results....
When UCLA’s Dr. Araceli Espinosa-Jeffrey sent human brain cells into space, her goal was to gain a better understanding of how neural stem cells grow and develop in microgravity. That understanding is key to discovering more about the serious issues of intracranial hypertension affecting astronauts returning from space. The information may also one day be used to further cell replacement therapies...
Merck and Baylor College of Medicine have announced an extension of their ongoing collaboration to advance a manufacturing platform to fight Covid-19, designed to accelerate transition to Phase 1 clinical trials. “Vaccine manufacturing is extremely complicated, so we are collaborating on a process development approach to accelerate manufacturing of Baylor’s Covid-19 vaccine candidate...
By Professor Georgina Ellison-Hughes, Dr Rocio Martinez-Nunez and Dr Rui Ribeiro Galao, Faculty of Life Sciences & Medicine, King’s College London. With promises of antibody tests being rolled out in the next few days to NHS and care staff in England, and retailers told not to send home-testing kits as their accuracy is questioned, it is timely to consider what we do and don’t know about these tests....