Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, is pleased to announce the extension of the ISOLUTE® PLD+ protein and phospholipid removal product line to include the versatile tabless 1 mL column format, for the clean-up of blood based matrix samples for analysis by LC-MS/MS.
ISOLUTE® PLD+ 96-well plates and columns combine protein and phospholipid removal into a single product providing very effective and extremely simple sample clean-up for LC-MS/MS analysis. The new format is ideal for lower throughput applications, or for laboratories that have variable sample numbers to process. Up to 96 columns can be processed using specially designed base plates, eliminating the problem of wasted unused...
Proteomics research is increasingly involved in the development of modern clinical medicine from the identification of drug targets, the validation of biomarkers, and optimization of resulting drug leads and assays.
Pharmaceutical and diagnostic companies spend tens of billions of dollars on translational research, which has increased the focus on instruments capable of powerfully assaying and identifying proteins implicated in disease pathways. The Proteomic Research Market Opportunity, Defined: Report analyst Emil Salazar examines proteomics research processes in detail and in terms of their instrument and technological requirements relating to mass spectrometry...
Asynt has developed DrySyn NMR Heating Blocks to enable safe, effective and uniform heating of up to 10 NMR tubes on a conventional hotplate stirrer.
This new DrySyn unit allows you to use standard NMR tubes as a reaction vessel for applications including catalyst screening experiments and reaction monitoring as well as studying broad peaks, temperature dependent solubility issues and conformational changes. Unlike heating in problematic oil baths, using a DrySyn NMR Heating Blocks allows you to analyse the contents of your NMR tube almost immediately without removal of residual oil on the outside of the glassware...
Bruker announced that its NMR FoodScreener™ laboratory for food authenticity and quality determination, located in Rheinstetten, Germany, has been granted ISO/IEC 17025 accreditation.
The certificate has been awarded for Bruker’s validated methods for the determination of ingredients and measures of authenticity and quality of liquid foods and food extracts by NMR spectroscopy. Government and private analytical service laboratories offering NMR-based testing for food authenticity and quality with Bruker’s standard operating procedures (SOPs) and validated methods can now more easily get these NMR methods accredited in their lab. Christian Kost, Managing Director of Winespin-Analytics GmbH...
European Mass Spec/Chromatography Sales and Service Company KRSS Ltd have entered into a collaboration with the University of East Anglia/Norwich Medical School leading to the opening of a clinical application support laboratory in KRSS’s new 17,000sq ft. state-of-the art facility based in Runcorn, Cheshire.
The new facility will initially target clinical applications such as Total/Free Urinary and Plasma Metanephrines, Catecholamines, Vitamin D, Female Testosterone (Androgens), Steroids and Therapeutic Drugs. KRSS customers will have access to technical support from a Clinical applications team, headed up by John Dutton and Professor Bill Fraser of UEA, who have over 60 years’ experience in clinical laboratories. The agreement will benefit from the technical...
Genevac, specialists in solvent removal, have developed a suite of proprietary technological solutions to facilitate post purification sample handling, including reformatting.
For labs undertaking purification using Normal Phase HPLC, SFC or Flash chromatography – removal of organic solvents can be simply, productively and safely carried out in a Genevac centrifugal evaporator (EZ-2, ROCKET, Rocket Synergy or HT Series III). Where the nature of the sample being concentrated can lead to solvent bumping (e.g. natural products) - Genevac's DriPure® technology is proven to completely eliminate this troublesome and...
Asynt reports on how chromatography specialists - Reach Separations Ltd. are benefiting from the installation of an onsite nitrogen generator at their laboratories in Nottingham, UK.
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
"Analytical Challenges And Solutions For Difficult Pharmaceutical Molecules"
NOVEMBER 10TH & 11TH 2015 AT GSK WARE HERTS
The Chromatographic Society is an internationally connected organisation and UK registered scientific charity devoted to the promotion and dissemination of knowledge on all aspects of chromatography and related separation techniques.
As we are sure you aware, solid glass limited volume vials are usually more expensive than what you or your customers would like to pay for.
This isn’t a new problem. As a matter of fact, in the late-70’s when Jerry Finneran was working for another company, in the plastics department, he was trying to think of ways to reduce the cost of such a vial. He suggested that using a plastic vial, since plastic is less expensive than glass, and bonding a glass insert inside it, which would maintain the glass surface being in contact with samples that the lab techs required, would reduce the cost of the vial....
Read MoreThermo Fisher Scientific Receives IVDD CE Mark for its Thermo Scientific Prelude MD HPLC, Endura MD Mass Spectrometer and ClinQuan MD SoftwareSep 23, 2015
Now available to clinical laboratories in Europe for general in vitro diagnostic use
Thermo Fisher Scientific, the world leader in serving science, today announced that it received the in vitro diagnostics device (IVDD) CE mark for its Thermo Scientific Prelude MD HPLC, Endura MD mass spectrometer and ClinQuan MD software. Available for general in vitro diagnostic use in Europe, clinical laboratories now have access to a high performance liquid chromatograph, mass spectrometer and LC-MS software designed and manufactured for in...
Redesigned Sartobind® membrane adsorber capsules offer higher binding capacities, reduced void volumes, less buffer consumption and lower operational costs
To more effectively recover large molecular weight proteins, such as blood factors and conjugated proteins or viruses and virus-like particles, Sartorius Stedim Biotech (SSB) has reconfigured its Sartobind® membrane chromatography capsules. A range of capsule sizes with a 4 mm bed height is now available from the 1 mL nano unit up to the new 2.5 L jumbo version. The capsules’ upstream flow channels have been optimized, and an internal core...
Phenomenex, Inc. and the Tecan Group (SIX Swiss Exchange: TECN) today announced a collaboration to co-market automated solid phase extraction (SPE) sample preparation solutions.
The two companies will jointly market Phenomenex Strata™ and Strata-X SPE sorbents adapted to Tecan’s Freedom EVO® series of robotics workstations. The solution is especially geared to high-throughput customers in pharmaceutical research, clinical and food testing environments using mass spectrometry detection methods. As part of the global agreement, Tecan will provide the instruments and automation support, and Phenomenex will provide the extraction...
Microsaic Miniaturised Mass Spectrometry Instruments Now Compatible with the Clarity Chromatography Control Platform
Microsaic Systems plc (AIM: MSYS), the high technology company developing the next generation of miniaturised mass spectrometry (MS) instruments, is pleased to announce that its product range is now compatible with Clarity Chromatography Software, the advanced Chromatography Data Station developed by Data Apex.
CAMECA Delivers Local Electrode Atom Probe (LEAP) To US Naval Research Laboratory for Advanced Materials Development
The US Naval Research Laboratory (NRL) has taken delivery of the US Department of Defense’s first Local Electrode Atom Probe (LEAP) microscope. The high- performance atom probe from CAMECA, a unit of AMETEK Materials Analysis, is used in advanced materials analysis to provide precise atom-by-atom identification, 3-D spatial positioning, and accurate atomic-scale reconstruction of a material’s microstructure. Since their development in the 1960s, atom probes have contributed to...
Magritek, a leading provider of compact NMR and MRI instruments, announce the posting of a new educational video on following chemical reactions in real time on the bench using the Magritek Spinsolve NMR spectrometer.
Given by CEO Dr Andrew Coy, this lecture is one of a series of webinars organised by software provider Mestrelab on the growth in benchtop NMR solutions. Mestrelab Research produces a software program called Mnova which is widely used by organic chemists to analyse NMR spectra. Magritek customers often use MNova to carry out their NMR data processing and analysis. Mestrelab organised a series of webinars on benchtop NMR and invited...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer the Chemistry Department of the University of Queensland where it is in use in the undergraduate laboratory curricula.
Dr Philip Sharpe is a teaching-focused academic in the School of Chemistry & Molecular Biosciences at the University of Queensland, Australia. His active research interests are in the field of chemistry education research, particularly student learning within the laboratory environment. His goal is to remove the barriers that hinder student success in the laboratory and to provide situations that allow students to maximize their learning. As the academic in charge of the first year chemistry laboratory, Dr Sharpe...
Analytik, leading suppliers of innovative analytical instrumentation, announce the availability of ASD's new FieldSpec 4 High Resolution NG portable spectroradiometer.
This is designed to meet the specifications of NASA’s next generation of airborne visible/infrared imaging spectrometer. AVIRISng is an acronym for the Airborne Visible InfraRed Imaging Spectrometer - Next Generation. It has been developed by government laboratories in the USA, NASA and JPL, to provide continued access to high signal-to-noise ratio imaging spectroscopy measurements in the solar reflected spectral range. To complement this, ASD have introduced their...
The global prepacked chromatography columns market is estimated to grow at a CAGR of 8.2% from 2014 to 2019.
Rising demand of purification of antibodies, recombinant proteins, vaccines; and virus titer reduction are some of the factors driving the growth of pre-packed columns market. The cost-effective purification of biological drugs, specifically monoclonal antibodies (mAbs) has been increasing the market potential of pre-packed columns. However, there is a paradigm shift towards disposable pre-packed columns. The market for pre-packed...
The newly developed mass spectrometer with inductively coupled plasma from Analytik Jena, PlasmaQuant ® MS, provides ADD 10 — the all-digital detection technology covering 10 orders of magnitude linear dynamic range.
Equipped with advanced control technology the ADD 10 automatically dilutes signals up to 4 orders of magnitude electronically. This guarantees optimum signal detection independent from the concentration level of an element in the sample. The ADD 10 thus emphasizes the flexible and user-friendly concept of PlasmaQuant ® MS systems. In addition to that, this technology enables a previously unattained detector lifetime, thereby improving the...
Ocean Optics’ spectrometer assures special effects color purity and safety for Le Maitre
Spectrometers from Ocean Optics are being used by Le Maitre Ltd (Surrey, England) to ensure the quality and safety of its close proximity pyrotechnics. Ocean Optics spectrometers measure plasma emission and emissive color of effects used in theater productions, concerts, and sporting events. The measurements help Le Maitre ensure these explosive displays are consistently amazing, and most important, safe. Le Maitre Pyrotechnics Developer Hamish...
Princeton Chromatography Inc., world leaders in the development of novel and innovative SFC stationary phases, have published a new SFC & HPLC columns catalogue.
Princeton Chromatography were the first company to develop and market the popular 2-Ethylpyridine phase which was launched in 2001 and later the 4-Ethylpyridine phase. PrincetonSFC 2-Ethylpyridine has become the column of choice for achiral SFC analysis of basic compounds. This phase generally requires no addition of amines to the eluent, producing excellent peak shape and reproducibility.
Cecil Instruments have launched a newly developed low cost easy to use HPLC range. The new Merit systems expand its proven comprehensive Adept HPLC range.
The Merit range is designed to provide a completely new level of ease of use, dramatically reducing the time for software familiarisation. Each Merit system incorporates the proven, reliable, consistent, high specification, ultra-low drift and durable performance of the trusted Cecil pumps and UV/Visible detectors. Each system is fully PC controlled, using Merit software, to achieve and save high quality chromatograms. Automatic integration is provided, without the need for further baseline adjustment. Qualitative work is remarkably easy. The fast checking of multi-component samples is easy....
ISOLUTE® PLD+ 96-well plates and columns combine protein and phospholipid removal into a single product providing very effective and extremely simple sample clean-up for LC-MS/MS analysis. The new format is ideal for lower throughput applications, or for laboratories that have variable sample numbers to process. Up to 96 columns can be processed using specially designed base plates, eliminating the problem of wasted unused...
Pharmaceutical and diagnostic companies spend tens of billions of dollars on translational research, which has increased the focus on instruments capable of powerfully assaying and identifying proteins implicated in disease pathways. The Proteomic Research Market Opportunity, Defined: Report analyst Emil Salazar examines proteomics research processes in detail and in terms of their instrument and technological requirements relating to mass spectrometry...
This new DrySyn unit allows you to use standard NMR tubes as a reaction vessel for applications including catalyst screening experiments and reaction monitoring as well as studying broad peaks, temperature dependent solubility issues and conformational changes. Unlike heating in problematic oil baths, using a DrySyn NMR Heating Blocks allows you to analyse the contents of your NMR tube almost immediately without removal of residual oil on the outside of the glassware...
The certificate has been awarded for Bruker’s validated methods for the determination of ingredients and measures of authenticity and quality of liquid foods and food extracts by NMR spectroscopy. Government and private analytical service laboratories offering NMR-based testing for food authenticity and quality with Bruker’s standard operating procedures (SOPs) and validated methods can now more easily get these NMR methods accredited in their lab. Christian Kost, Managing Director of Winespin-Analytics GmbH...
The new facility will initially target clinical applications such as Total/Free Urinary and Plasma Metanephrines, Catecholamines, Vitamin D, Female Testosterone (Androgens), Steroids and Therapeutic Drugs. KRSS customers will have access to technical support from a Clinical applications team, headed up by John Dutton and Professor Bill Fraser of UEA, who have over 60 years’ experience in clinical laboratories. The agreement will benefit from the technical...
For labs undertaking purification using Normal Phase HPLC, SFC or Flash chromatography – removal of organic solvents can be simply, productively and safely carried out in a Genevac centrifugal evaporator (EZ-2, ROCKET, Rocket Synergy or HT Series III). Where the nature of the sample being concentrated can lead to solvent bumping (e.g. natural products) - Genevac's DriPure® technology is proven to completely eliminate this troublesome and...
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
This isn’t a new problem. As a matter of fact, in the late-70’s when Jerry Finneran was working for another company, in the plastics department, he was trying to think of ways to reduce the cost of such a vial. He suggested that using a plastic vial, since plastic is less expensive than glass, and bonding a glass insert inside it, which would maintain the glass surface being in contact with samples that the lab techs required, would reduce the cost of the vial....
Thermo Fisher Scientific, the world leader in serving science, today announced that it received the in vitro diagnostics device (IVDD) CE mark for its Thermo Scientific Prelude MD HPLC, Endura MD mass spectrometer and ClinQuan MD software. Available for general in vitro diagnostic use in Europe, clinical laboratories now have access to a high performance liquid chromatograph, mass spectrometer and LC-MS software designed and manufactured for in...
To more effectively recover large molecular weight proteins, such as blood factors and conjugated proteins or viruses and virus-like particles, Sartorius Stedim Biotech (SSB) has reconfigured its Sartobind® membrane chromatography capsules. A range of capsule sizes with a 4 mm bed height is now available from the 1 mL nano unit up to the new 2.5 L jumbo version. The capsules’ upstream flow channels have been optimized, and an internal core...
The two companies will jointly market Phenomenex Strata™ and Strata-X SPE sorbents adapted to Tecan’s Freedom EVO® series of robotics workstations. The solution is especially geared to high-throughput customers in pharmaceutical research, clinical and food testing environments using mass spectrometry detection methods. As part of the global agreement, Tecan will provide the instruments and automation support, and Phenomenex will provide the extraction...
Microsaic Systems plc (AIM: MSYS), the high technology company developing the next generation of miniaturised mass spectrometry (MS) instruments, is pleased to announce that its product range is now compatible with Clarity Chromatography Software, the advanced Chromatography Data Station developed by Data Apex.
The US Naval Research Laboratory (NRL) has taken delivery of the US Department of Defense’s first Local Electrode Atom Probe (LEAP) microscope. The high- performance atom probe from CAMECA, a unit of AMETEK Materials Analysis, is used in advanced materials analysis to provide precise atom-by-atom identification, 3-D spatial positioning, and accurate atomic-scale reconstruction of a material’s microstructure. Since their development in the 1960s, atom probes have contributed to...
Given by CEO Dr Andrew Coy, this lecture is one of a series of webinars organised by software provider Mestrelab on the growth in benchtop NMR solutions. Mestrelab Research produces a software program called Mnova which is widely used by organic chemists to analyse NMR spectra. Magritek customers often use MNova to carry out their NMR data processing and analysis. Mestrelab organised a series of webinars on benchtop NMR and invited...
Dr Philip Sharpe is a teaching-focused academic in the School of Chemistry & Molecular Biosciences at the University of Queensland, Australia. His active research interests are in the field of chemistry education research, particularly student learning within the laboratory environment. His goal is to remove the barriers that hinder student success in the laboratory and to provide situations that allow students to maximize their learning. As the academic in charge of the first year chemistry laboratory, Dr Sharpe...
This is designed to meet the specifications of NASA’s next generation of airborne visible/infrared imaging spectrometer. AVIRISng is an acronym for the Airborne Visible InfraRed Imaging Spectrometer - Next Generation. It has been developed by government laboratories in the USA, NASA and JPL, to provide continued access to high signal-to-noise ratio imaging spectroscopy measurements in the solar reflected spectral range. To complement this, ASD have introduced their...
Equipped with advanced control technology the ADD 10 automatically dilutes signals up to 4 orders of magnitude electronically. This guarantees optimum signal detection independent from the concentration level of an element in the sample. The ADD 10 thus emphasizes the flexible and user-friendly concept of PlasmaQuant ® MS systems. In addition to that, this technology enables a previously unattained detector lifetime, thereby improving the...
Spectrometers from Ocean Optics are being used by Le Maitre Ltd (Surrey, England) to ensure the quality and safety of its close proximity pyrotechnics. Ocean Optics spectrometers measure plasma emission and emissive color of effects used in theater productions, concerts, and sporting events. The measurements help Le Maitre ensure these explosive displays are consistently amazing, and most important, safe. Le Maitre Pyrotechnics Developer Hamish...
Princeton Chromatography were the first company to develop and market the popular 2-Ethylpyridine phase which was launched in 2001 and later the 4-Ethylpyridine phase. PrincetonSFC 2-Ethylpyridine has become the column of choice for achiral SFC analysis of basic compounds. This phase generally requires no addition of amines to the eluent, producing excellent peak shape and reproducibility.
The Merit range is designed to provide a completely new level of ease of use, dramatically reducing the time for software familiarisation. Each Merit system incorporates the proven, reliable, consistent, high specification, ultra-low drift and durable performance of the trusted Cecil pumps and UV/Visible detectors. Each system is fully PC controlled, using Merit software, to achieve and save high quality chromatograms. Automatic integration is provided, without the need for further baseline adjustment. Qualitative work is remarkably easy. The fast checking of multi-component samples is easy....