Thermo Fisher Scientific Inc., the world leader in
serving science, today announced
Maybridge HitFinderTM-Plus, a collection
of 3,000 pre-plated drug-like screening compounds that is ideal for a variety
of drug discovery programs. The new library expands the industry leading
Maybridge
HitFinder collection of 14,400 screening compounds and is available as
an "add-on" for current
HitFinder users at reduced upgrade fees.
Thermo
Fisher created the new
HitFinder-Plus collection using an industry
standard clustering algorithm, based on standard Daylight Fingerprints and a
Tanimoto level of 0.55, to select a statistically representative sample of the
full 56,000 compound Maybridge Screening Collection. All compounds fit
Lipinski Ro5 guidelines for "drug-likeness" and have a purity level
of greater than 90 percent. They have also been selected to be non-reactive,
ensuring fewer false positives and higher-quality results.
When
combined, the pre-plated
Maybridge HitFinder and
HitFinder-Plus collections
contain more than 17,400 unique drug-like screening compounds, providing a
large, but manageable library that is flexible enough for a range of drug
discovery programs. These pre-selected, diverse collections are conveniently
supplied as dry films in Thermo Scientific Matrix 96-shallow-well plates or
384-well microplates. For further convenience, users can view and assess the
exact structures in each plate by browsing the collections online at
www.chem.maybridge.com/hitfinder. This ensures that the process of
identifying potential drug leads using Maybridge compounds is as easy and
cost-effective as possible.
For further information on this product, please visit
www.maybridge.com.
About Maybridge
Maybridge, a Thermo Fisher Scientific brand,
is well-known for highly innovative drug-like molecules and screening compounds
for drug discovery and development. With products available for both lab and
development scale, the Maybridge line features new heterocyclic and phenyl
ring-based chemical building blocks, including a unique and expanding range of
reactive intermediates. For more information about Maybridge brand products,
visit
www.maybridge.com or call +44 18 40 77
05 67.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science.
Our mission is to enable our customers to make the world healthier, cleaner and
safer. With revenues of nearly $11 billion, we have approximately 37,000
employees and serve customers within pharmaceutical and biotech companies,
hospitals and clinical diagnostic labs, universities, research institutions and
government agencies, as well as in environmental and process control
industries. We create value for our key stakeholders through two premier
brands, Thermo Scientific and Fisher Scientific, which offer a unique
combination of continuous technology development and the most convenient
purchasing options. Our products and services help accelerate the pace of
scientific discovery, and solve analytical challenges ranging from complex
research to routine testing to field applications. Visit
www.thermofisher.com.
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