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All articles from Merck

  Experts to Discuss Improvements to Face Masks for Optimal Virus Transmission Control Amid Covid-19 Pandemic

Conversations on face mask efficacy and supply for frontline workers and the general public have been heated topics amid the Covid-19 pandemic. As the first in a series of monthly “Pandemic Response Catalyst Conversations,” three leading scientific experts will provide facts and data-driven insights on the current global mask supply, filtration properties of masks and a preview of technological innovations improving masks...


  Merck Boosts Commercial Viral Vector and Gene Therapy Manufacturing Capacity

Merck, a leading science and technology company, has announced a second Carlsbad, California, U.S.A.-based facility for its BioReliance® viral and gene therapy service offering. The new, € 100 million commercial facility is expected to open next year. “Viral vector manufacturing has transitioned from a niche industry to the cornerstone of the future of biopharmaceuticals,” said Udit Batra, member of the Merck Executive Board and CEO, Life Science....


  Merck Accelerates Readiness of Bioprocessing Facility of the Future

Merck has unveiled the next component of its BioContinuum™ Platform, the Bio4C™ Software Suite, creating a first-of-its-kind ecosystem that combines process control, analytics and plant-level automation. This transformative software suite will allow users to look across the entire manufacturing process versus individual operational units, giving biomanufacturers complete process control and deep insights...


  Merck Supports Jenner Institute to Reach First Milestone in Covid-19 Vaccine Manufacturing

Merck, a leading science and technology company, and The Jenner Institute today announced that the Jenner Institute has laid the foundation for large-scale production of its Covid-19 vaccine candidate, ChAdOx1 nCoV-19. With patients enrolled for clinical trials for this vaccine, rapid development of the large-scale manufacturing process is a critical step in quickly and safely delivering it from the lab to patients....


  Merck’s New LANEXO™ System to Improve Scientists’ Productivity in the Lab

Merck has launched its LANEXO™ Lab Inventory, Safety and Compliance Management System, a new digital laboratory informatics solution designed to drastically reduce1 time in labs and improve data quality and traceability. “Today, 85 percent of labs are using paper or Excel to manage consumables data, and 25 percent of time is spent managing these data — taking scientists away from bench research,” said Jean-Charles Wirth...


  Merck to Manufacture Elypta’s Liquid Biopsy Kits

Merck, a leading science and technology company, has announced that it has been selected by Swedish molecular diagnostics firm Elypta as the contract manufacturer for Elypta’s clinical diagnostic liquid biopsy kits. The kits analyze metabolites deregulated in several cancer types, making diagnoses more accurate. “Both small and large diagnostic and clinical testing kit manufacturers struggle to find high quality, reliable contract manufacturing organizations like us,” said Jean-Charles Wirth, head of Applied Solutions, Life Science, at Merck....


  New BrightLab™ cloud-based inventory management and instrument connectivity platform for research scientists.

Merck, a leading science and technology company, has introduced its BrightLab™ cloud-based inventory management and instrument connectivity platform for research scientists. The new software includes an electronic lab notebook, which allows scientists and lab managers to track and update experiments from any computer or mobile device. “In today’s research environment, analog methods of documentation and analysis often take us away from the research itself....


  BioMed X Starts New Research Program in Autoimmune Diseases with Merck

BioMed X has announced the start of a new joint research group in collaboration with Merck. With this new group, BioMed X and Merck extend their ongoing collaboration to a total of six joint research projects at the BioMed X Innovation Center in Heidelberg, Germany. The new project will focus on the role of the intestinal epithelial barrier in the development and exacerbation of autoimmune diseases such as systemic lupus erythematosus (SLE) and multiple sclerosis (MS)....


  Merck Licenses Foundational CRISPR Integration Technology to Promega

Merck, a leading science and technology company, has announced that it has signed a license agreement providing Promega Corp., a global life science manufacturer based in Madison, Wisconsin, USA access to Merck’s foundational CRISPR intellectual property. Promega will use Merck’s CRISPR genome-editing technology to create research products and services, including those for drug development.


  Japan and Singapore Grant CRISPR Patents to Merck

Merck, a leading science and technology company, today announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide. “Paired nickases represent a significant step in increasing specificity through a highly flexible and efficient approach to reduce off target effects in gene editing,” said Udit Batra....


  Merck Licenses CRISPR Gene-Editing Technology to Evotec

Merck, a leading science and technology company, has announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for Evotec’s commercial and internal research purposes....


  Merck Launches Seed Fund for Startups in China

Merck, a leading science and technology company, has announced an RMB 100 million (€ 13 million) seed fund targeted at startups in China. The company also officially opened its innovation hub in Shanghai and announced plans to officially open a second innovation hub in Guangzhou in November. “Our RMB 100 million China seed fund underlines our commitment to invest in the Chinese market,” said Stefan Oschmann, CEO and Chairman of the Executive Board of Merck....


  Merck Granted 20 CRISPR Patents Total Worldwide

Merck, a leading science and technology company, has announced that the European, Israeli, South Korean and U.K. intellectual property offices have issued formal notices allowing seven additional Merck patent application claims covering CRISPR gene-editing technology, bringing the number of patents to 20 worldwide....


  Merck Acquires BSSN Software to Accelerate Customers’ Digital Transformation in the Lab

Merck has acquired BSSN Software, a Darmstadt, Germany-based laboratory informatics company that makes data more readily accessible for ease of integration, collaboration, analysis and long-term archiving. “BSSN Software and the capabilities that it brings will allow Merck’s customers to better use and share their scientific data — the most important part of laboratory experiments,” said Jean-Charles Wirth, head of Applied Solutions at the Life Science business sector of Merck...


  Merck and Broad Institute Announce CRISPR License Framework to Encourage Innovation

Merck, a leading science and technology company, and the Broad Institute of MIT and Harvard (Boston, Massachusetts) have announced an agreement to offer non-exclusive licenses to CRISPR intellectual property (IP) under their respective control for use in commercial research and product development....


  Merck and Heisenberg Quantum Simulations Cooperate in Quantum Computing

merckThree-year cooperation between both companies. Unique approach to quantum chemistry on near-term quantum computers. Merck, a leading science and technology company, today announced a three-year cooperation with Heisenberg Quantum Simulations (HQS), a startup based in Karlsruhe, Germany. The cooperation between the startup and Merck Digital will focus on applying and commercializing software...


  Merck and Rigaku form Partnership to Develop Novel Molecular Structure Analysis Technology

Merck and Rigaku Corp. have signed a joint development agreement to develop lab consumables based on highly innovative crystalline sponge technology. Merck and Rigaku are collaborating to develop commercially available lab solutions employing highly innovative crystalline sponge technology. Merck will develop lab consumables to determine the absolute chemical structure of substances on sub-microgram scale.....


  Merck Awards Grants to Biotechs Focused on Traumatic Brain Injury, Vaccine Development and Chronic Pain

merckMerck, a leading science and technology company, today announced the winners of its Advance Biotech Grant program in North America during its Biotech Start-up Summit at the Cambridge Innovation Center (Massachusetts, U.S.). The grant is given to small- and mid-size biotechnology companies that need funding and expertise to get their therapies to market. “With more than 60 percent of drugs in the pipeline today...


  Merck Opens Application Phase for Next Accelerator program

Merck, a leading science and technology company, has announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at its China Innovation Hub in Shanghai.


  Merck Joins TRANSVAC2 Program to Advance Vaccine Development and Manufacturing


Merck, a leading science and technology company, announce its participation in a collaboration with the Vaccine Formulation Institute and the European Vaccine Initiative. The effort will provide vaccine process development training courses within TRANSVAC2, a collaborative infrastructure project under Horizon 2020. “Involvement in this project is a natural extension to our longtime focus on accelerating vaccine....


  Merck Lectureship 2019 Awarded to Susumu Kitagawa

Merck, a leading science and technology company, has announced that Susumu Kitagawa, Professor at the Institute for Integrated Cell–Material Sciences at Kyoto University, Japan, has been named the sixteenth recipient of the Emanuel Merck Lectureship. He is being recognized for his pioneering scientific work in the field of metal organic frameworks (MOFs). His fundamental contributions to the development of this innovative class of nanoporous materials could lead to new ways...


  Merck Signs Exclusive Agreement with HistoCyte Laboratories to Distribute Pathology Technology

MerckMerck, a leading science and technology company, has announced that it has entered into an agreement with HistoCyte Laboratories Ltd, Tyne, U.K., to be the exclusive multinational distributor of the company’s portfolio of cell line reference products for immunohistochemistry and in situ hybridization....


  Merck Introduces Stericup Quick Release System for Improved Cell Culture Filtration

Merck, a leading science and technology company, has launched the new Stericup® Quick Release 500 ml vacuum filtration system, a filter bottle system ideally suited for sterile filtration of cell culture media, buffers and reagents.

merckThe Stericup® Quick Release system is the next generation of the original Stericup® Sterile Vacuum Filtration System, which has been a staple in labs around the world for decades. The improved liquid sterile filtration system offers ergonomic design updates that optimize user control and...


  Small but Mighty: Merck’s ReadyPlate 55 Agar Plates for More Efficient Water and Filterable Beverage Testing

Merck’s ReadyPlate™ 55 ready-to-use agar plates offer streamlined, convenient and efficient sample testing for quality control of water and filterable beverages.

MerckWith a diameter of just 55 mm, ReadyPlate™ 55 plates are much smaller than standard 90 mm plates, freeing up valuable space in the incubator while reducing waste. The plates are available in a variety of certified kits which combine the agar plates with matching membranes needed for testing....


  Merck's SOLu-Trypsin Enzyme Brings Stability to Mass Spectrometry

Merck's Advanced Proteomics Grade SOLu-Trypsin is an exclusive, solution stable enzyme for mass spectrometry.

merckDesigned to be stable in solution when refrigerated, SOLu-Trypsin can be used immediately without preparation. Other forms of trypsin require thawing or reconstitution and must be discarded if not used immediately. SOLu-Trypsin allows excess product to be saved for future use, thus eliminating unnecessary waste and cost.....


  Merck Develops Alternative CRISPR Genome Editing Method

Merck, a leading science and technology company, has developed a new genome editing tool that makes CRISPR more efficient, flexible and specific, giving researchers more experimental options and faster results that can accelerate drug development and access to new therapies.

merckThis new technique, called "proxy-CRISPR," provides access to previously unreachable areas of the genome. Most natural CRISPR systems, found in bacteria, cannot work in human cells without significant re-engineering....


  Merck Provides Upgraded Manufacturing Capabilities to BioInvent with Single-use Mobius Bioreactors

Merck has announced that BioInvent International AB, a Swedish company which develops novel immuno-regulatory antibodies to treat cancer, is upgrading and expanding its drug manufacturing facility with a full line of Merck’s Mobius® single-use bioreactors.

merckBioInvent will add 3-, 50-, 200- and 1000-liter bioreactors to its upstream facility in Lund, Sweden, expanding capacity and improving flexibility and scalability....


  Merck Advances Lab Water Purification Technology with Milli-Q IQ 7000 System

Merck, a leading science and technology company, has announced the global launch of the Milli-Q® IQ 7000 system, the seventh-generation Milli-Q® water purification innovation.

merckThis launch marks 50 years of providing ultrapure water to scientists in laboratories all over the world. The company announced details about the water purification system during a press briefing at the Pittcon Conference & Expo 2017 in Chicago, Illinois.


  Merck's Integritest 5 Instrument Provides Integrity Testing, Assurance

Merck's new Integritest® 5 instrument is an easy-to-use, portable and fully automated integrity test system for verification of filters and processing equipment.

merckThe latest model of the first commercially available automated integrity test instrument introduced more than 25 years ago now incorporates an improved algorithm to simplify test creation and accelerate test completion. The user-friendly software makes it easy to set up and manage users and tests, while offering a depth of advanced functionality for those who need additional options....


  Merck Introduces New Calibration Kit for In Vitro Diagnostic Use

Merck, a leading science and technology company, today announced the introduction of its new testosterone calibrator kit for in vitro diagnostic (IVD) use.

merckThe certified kit allows users to calibrate assays and verify calibrations, and is the first of its kind to receive CE mark approval, indicating compliance with the European Union's Medical Device Directive. The CE mark allows the kit to be marketed and sold in the European Union and in any country recognizing CE mark approval....


  Merck Introduces MILLIPLEX High Sensitivity Panel for Faster, More Economical Cytokine Assays

Product offers smaller sample volumes and four times higher throughput than traditional assays

merckMerck, a leading science and technology company, today launched the MILLIPLEX® MAP Human High Sensitivity cytokine panelfor faster and more cost-effective human cytokine assays. The new panel allows researchers to achieve four times higher throughput than traditional assays while using smaller sample sizes....


  Merck Collaborates with Evotec for Faster Target Identification Solution

Merck, a leading science and technology company, has announced that it has entered into a set of agreements with Evotec AG, whereby Evotec AG will provide screening services for Merck's collection of genetic reagents such as CRISPR and shRNA libraries.

merckCombining access to these libraries with Evotec's screening expertise offers an accelerated pathway to explore and identify new drug targets. "Drug discovery starts with the identification of new targets, a process that can be time- and labor-intensive," said Theresa Creasey, Head of Applied Solutions Strategic Marketing & Innovation, Life Science...


  Merck Launches Next-Generation Technology for Advanced Live Cell Imaging

Merck, a leading science and technology company, has launched the CellASIC® ONIX2 Microfluidic System for advanced live cell imaging.

merckThe system converts laboratory microscopes into powerful tools for live cell imaging to more effectively perform in-depth analysis of cellular mechanisms and behavior in a live environment....


  Merck Wins US Search Award for 'Best In-House' Team

Merck, a leading science and technology company, today announced that its digital acquisition marketing team won the 2016 US Search award for "Best In-House" team.

merckThe awards recognize organizations, agencies and individuals for excellence in search and digital marketing. "With more than 300,000 products, our website allows our customers in nearly every country to more easily find the exact products they need to advance their research," said Silji Abraham, Chief Information Officer, Merck Life Science.


  Microbial Testing Without the Burden

New EZ-Fit™ Filtration Units from Merck

MerckMerck has expanded its portfolio of EZ-Fit™ filtration units, ready-to-use, disposable filtration devices for bioburden testing. The new EZ-Fit™ filtration units come with a wide range of membrane sizes to suit all applications, and a new patented drain design to accelerate processing of turbid and hard-to-filter matrices....


  Merck Advances Water Purification Systems with New High-Throughput Line

Elix® High-Throughput water purification system delivers up to 9000 liters of pure water daily with real-time monitoring 

merckPurification technologies ensure constant water quality with low and predictable running costs. Merck, a leading science and technology company, have introduced the Elix® High-Throughput water purification system, providing laboratories with a reliable water purification solution for daily water volumes of up to 9000 liters...


  Merck Expands Excipients Portfolio, Adding Polymers for Sustained Release Injectables

Merck has entered into an agreement with PCAS S.A. to expand Merck’s excipients portfolio. Under the agreement, Merck will be the exclusive, global distributor of the Expansorb® line of biocompatible and biodegradable polymers.

merckThe portfolio will include 38 polymers for sustained release of small molecule and selected peptide injectables, allowing customers to optimize and precisely control release kinetics of final drug products. The ability to better control and sustain the release of drugs allows for delivery via reduced numbers of injections with the same therapeutic efficacy...


  Merck Expands Industry-Leading Emprove Program to Include Filtration and Single-Use Products

Emprove® risk assessment program provides easy access to information on materials used for drug product manufacturing

merckMerck has expanded its industry-leading Emprove® risk assessment program to include a selection of products for filtration and single-use processing. The program provides documentation and regulatory information on materials used in the manufacture of drug products.....


  Merck and University of Nairobi to Start Medical Oncology Fellowship Program

Program aims to improve access to cancer care in Africa and increase number of oncologists on the continent - Paediatric and adult medical fellowship planned for African doctors in India

University Nairobi

Merck, a leading science and technology company, today announced to start the first Merck Africa Medical Oncology Fellowship Program for Sub-Saharan African countries in partnership with University of Nairobi, Kenya. The program will be conducted at University of Nairobi and is part of Merck’s efforts to improve access to cancer care and strengthen the healthcare system in emerging markets....


  Merck Expands Popular Line of Guava Flow Cytometers

Merck, a leading science and technology company, is expanding its popular line of Guava® flow cytometers to include a high-power modulated green laser. 

MerckThe addition of a 532 nanometer laser expands the detection capabilities of the Guava® easyCyte instrument line to enable simultaneous detection of multiple fluorescent proteins. It also offers researchers more spectral choice using fluorescent reagents. More powerful violet, blue and red lasers are now standard in most configurations, meaning the Guava® cytometers are sensitive enough to detect subcellular particles as small as viruses....


  Merck Introduces IsoBag for Faster and Easier Transfer of Contact and Settle Plates

Merck, a leading science and technology company, today introduced the IsoBag™ for faster, easier and more convenient transfer of contact and settle plates to production isolators. 

merckThe new IsoBag™ offers a more streamlined alternative for environmental monitoring, and helps make workflows more efficient, productive and flexible. In traditional environmental monitoring workflows, single-bagged plates are decontaminated and stored in the isolator. Limited space in the isolator allows storage of only a small supply of ready-to-use plates. When this supply runs out, workflows are interrupted for...


  Merck Finishes Record Year 2015 Stronger

Merck, a leading science and technology company, reported record results for 2015, emerging stronger from the transformation process that started in 2007. Net sales and EBITDA pre exceptionals were higher than ever before in Merck’s history of nearly 350 years.

Merck“2015 was not only an eventful, but above all a very successful year for Merck. We again achieved profitable growth. By acquiring Sigma-Aldrich, we successfully completed the portfolio realignment of recent years. In immuno-oncology, we initiated six pivotal clinical trials. Research advances and future-oriented investments form the foundation for future success. And our new bold and vibrant branding shows what makes Merck unique,” said Karl-Ludwig Kley, Chairman of the Executive Board....


  Life Science Leader Merck Launches New Innovations at Pittcon 2016

Merck, a leading science and technology company launch a range of new products for separation and analysis

merckThe innovations include high performance liquid chromatography (HPLC) and capillary gas chromatography (GC) columns, and tools for effective analysis of water and easier sample preparation. "We are committed to providing innovations that help our customers solve their toughest problems, advance science and accelerate access to health care around the world," said Udit Batra, CEO of Merck's life science business


  New: Heipha ICRplus Neutralizer A Contact Plates for Improved Detection of Microorganisms in Isolators and Cleanrooms

Merck Millipore's heipha ICRplus Neutralizer A contact plates improve detection of microorganisms on disinfected surfaces in isolators and cleanrooms.

merck milliporeCommon disinfectants may contain residues from a variety of sources that inhibit the detection of microorganisms during surface monitoring, which can lead to false negative results. Heipha Neutralizer A ICRplus contact plates allow the detection of microorganisms in the presence of many disinfectants, including those which cannot be sufficiently inactivated by common neutralizers, such as polysorbate 80, lecithin, histidine and thiosulfate...


  New SNAP i.d. 2.0 System for Immunohistochemistry Minimizes Slide Handling

Merck Millipore, the Life Science division of Merck, has introduced the SNAP i.d.® 2.0 Protein Detection System for Immunohistochemistry (IHC), which streamlines immunohistochemistry workflows and significantly decreases slide handling time.

merck milliporeThe system enables parallel processing of up to 24 tissue slides at a time, making it easier to apply consistent conditions and reduce potential process variability inherent in manual IHC methods. The system's intuitive format reduces slide handling and speeds wash steps during blocking, washing, antibody incubation and labeling. A controlled vacuum force removes solutions evenly from all slides at once, in seconds. This approach systemizes the handling of...


  Merck to Acquire Sigma-Aldrich to Enhance Position in Attractive Life Science Industry

Merck and Sigma-Aldrich today announced that they have entered into a definitive agreement under which Merck will acquire Sigma-Aldrich for $17.0 billion (€13.1 billion), establishing one of the leading players in the $130 billion global life science industry.

merckMerck will acquire all of the outstanding shares of Sigma-Aldrich for $140 per share in cash. The agreed price represents a 37% premium to the latest closing price of $102.37 on September 19, 2014, and a 36% premium to the one-month average closing price. The transaction is expected to be immediately accretive to Merck’s EPS pre and EBITDA margin. Merck expects to achieve annual synergies of approximately €260 million (approximately $340 million), which should be fully realized within three years after closing....


  Ready-to-Use EZ-Fit Filtration Unit from Merck Millipore Leverages Industry Leading Technology for More Efficient Bioburden Testing of Municipal Water, Environmental Samples and Beverages

Merck Millipore, the Life Science division of Merck, has launched the EZ-Fit™ Filtration Unit, a ready-to-use, disposable filtration device for bioburden testing.

merckThe system is faster and more efficient than traditional methods, resulting in increased reliability and streamlined workflows. The unit, which conforms to international standards (EP/USP) and water testing regulations, can be used for filtration of liquid samples including water, raw materials, in-process samples and final products. "The EZ-Fit™ Filtration Unit represents the latest addition to our comprehensive portfolio of products that facilitate and...


  Polyplus-transfection and Merck sign license & supply agreement for PEI-based transfection reagents

Polyplus-transfection SA, a privately-held company developing innovative technologies for molecular and cellular biology and Merck, a leading pharmaceutical, chemical and life science company with total revenues of EUR 11.2 billion in 2012, announce today a global prior use license agreement and extended supply agreement for Polyplus-transfection’s polyethylenimine (PEI) based transfection reagents. Financial details were not disclosed.

PolyPlus Transfection LogoPolyplus-transfection has granted Merck rights to the prior use of PEI for transfection. Polyplus-transfection will also supply Merck sites worldwide with batches of high quality linear PEI transfection reagent. The reagent is specifically formulated and subject to appropriate quality controls (transfection activity and microbiological tests). These ensure reliable, safe and reproducible protein production in medium to large scale....


  Elexopharm Enters Into Cardiovascular Collaboration With Merck & Co., Inc ElexoPharm GmbH announced today a collaboration and exclusive worldwide license agreement with Merck & Co., Inc. Whitehouse Station, New Jersey USA (also known as MSD outside of the US and Canada) through an affiliate to develop and commercialize novel candidates targeting aldosterone synthase for the potential treatment of cardiovascular disease.




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