Trial will analyze breath biomarkers to improve understanding of the treatment effects of a novel GSK pipeline drug candidate for COPD
Owlstone Medical Ltd, a diagnostics company developing a breathalyzer for disease, has announced that GSK, a world leader in respiratory, will incorporate Owlstone Medical’s Breath Biopsy platform into the clinical development programme of danirixin one of the novel drug candidates in its respiratory disease pipeline....
With courses delivered by world-renowned experts including Mel Euerby, Mark Powell, Diane Turner and others the new 2018 Hichrom training calendar is now available! Whether you are a relative newcomer to chromatography or a seasoned veteran, you can benefit from one of our courses.
Promoting interdisciplinary exchange between science and industry on the topics of regenerative medicine and cell therapy: this is the objective Sartorius will be pursuing by hosting its second Research Xchange Forum on March 20 and 21, 2018, at Sartorius College in Goettingen.
Experts from the biotechnology sector will report on the new developments in cell therapy. Sartorius has gained guest speakers Dr. Priscilla N. Kelly, editor of the journal Science, and Dr. Stefan W. Hell, the winner of the Nobel Prize in Chemistry 2014 and a professor at the Max Planck Institute for Biophysical Chemistry....
Read MoreUnlocking the Puzzle of Neurodegenerative DiseasesDec 12, 2017
Postnova Analytics reports that the Department of Molecular Biology & Biotechnology at the University of Sheffield (UK) is using their AF2000 Field Flow Fractionation system to investigate the mechanism of amyloid formation, a protein mis-folding process implicated to be the cause of Alzheimer’s and other neurodegenerative diseases.
Understanding the causes of neurodegenerative diseases is a huge challenge. Outbreaks of BSE (commonly known as mad cow disease) and the rise of Alzheimer’s as a leading cause of death has meant that there is increasing pressure to find a cure....
A single protein from a worm parasite may one day offer new therapeutic options for treating inflammatory bowel diseases like Crohn’s or Ulcerative Colitis, that avoid the potentially serious side effects of current immunosuppressant medications.
The study, published today in Nature Communications, demonstrates the discovery of a distinct new worm protein which mimics a cytokine found in humans, known as transforming growth factor-beta (TGF-β). The newly-discovered protein switches off inflammation by...
Secondary school pupils from across the north of Scotland have been experimenting with science over the past month as Robert Gordon University (RGU) continues its tradition of widening access to STEM subjects from an early age.
Members of RGU’s School of Pharmacy and Life Sciences have held a number of events in recent weeks to engage with youngsters and imprint the scientific curiosity that can take them far in their future careers. It began with the celebration for National Pathology Week, where...
SP Scientific announces publication of an independent study evaluating their LyoCapsule™ Freeze Dryer for pharmaceutical product formulation and process development.
The development of biopharmaceuticals often requires lyophilized formulations to produce stable drug products, beginning with laboratory experiments followed by scale-up to larger lyophilizers. Limited supply and high cost of Active Pharmaceutical Ingredient (API) can present major challenges during formulation and process development....
ROMIL is pleased to introduce PrimAg® conductivity reference solutions for the calibration of conductivity meters, further extending the comprehensive PrimAg® range of certified reference materials (CRMs).
Each calibrant or reference solution is supplied with a certificate of calibration detailing its calibrated or measured conductivity, as well as the associated uncertainty traced to ROMIL primary silver. PrimAg® is the clear choice when traceability is crucial....
€1.6 million grant will support ‘precise docking of very large DNA cargoes in genomes’ project
Sphere Fluidics, a company providing single cell analysis systems underpinned by its patented picodroplet technology, and Geneva Biotech, an EMBL spin-out developing world-class viral and non-viral DNA delivery systems, have received a €1.6 million grant from Eurostars....
The WHO reports an estimated 429,000 malaria deaths each year.
The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen....
The Bundesanstalt für Materialforschung und -prüfung (Federal Institute for Materials Research and Testing, BAM) and Analytik Jena AG have agreed to cooperate extensively in the research and development of optical spectrometry in the area of elemental analysis.
The two parties signed a corresponding cooperation agreement last week in Berlin. The focus of the two partners’ future research efforts will be on the development of new devices and applications for element determination. In this connection, the teams will work jointly on the further development...
Cambridge Epigenetix (CEGX), a pioneer in the development and application of epigenetic technologies, today announced the appointment of leading epigenetics-based therapeutics specialist, Professor Mark Dawson to its Scientific Advisory Board (SAB).
Professor Dawson brings a wealth of experience in the translation of cancer epigenetics research to clinical practice. The appointment further strengthens CEGX’s panel of opinion leaders providing expert advice across the Company’s key focus areas of epigenetics, oncology, liquid biopsy, diagnostic and therapeutic development....
Uniqsis has published an application note that describes an efficient 2-step synthesis of a library of pyrazoles under continuous flow-through conditions developed by chemists at GalChimia (Coruna, Spain) on a FlowSyn™ continuous flow reactor system.
Pyrazoles are an important and well represented chemotype in drug discovery displaying wide ranging biological actions that include analgesic, anti-inflammatory, antipyretic, tranquilizing, muscle relaxing, anticonvulsant, antidiabetic and antibacterial activities....
University of Leicester and Medical Research Council researchers lead study to monitor effectiveness of drugs on cancer patients
University and MRC researchers have developed a new platform for assessing anti-cancer drug efficacy in lung cancer that is more reflective of patient response than previously used model systems. The platform relies on the derivation of ‘explants’ from tumour tissue obtained fresh from surgery....
Astell Scientific, the UK’s leading autoclave manufacturer, is pleased to announce the launch of a new section of its website dedicated to hosting video.
The first area of focus is that of Astell’s advanced colour touchscreen controller, with a selection of seventeen video tutorials available to explain common functions and setting adjustments, making it easy for owners of Astell sterilizers to find the perfect setup. Each clip provides a walk-through of steps....
While colorectal cancer screening already saves many thousands of lives, there is still room for improvement.
By looking at a combination of specific proteins rather than at a single blood protein alone, substantially more patients with colorectal cancer and advanced adenomas could be detected. The study describing these findings, conducted by researchers from the Netherlands Cancer Institute and VU University Medical Center....
Laboratory water equipment experts Triple Red, have released their new “all in one” water system - the Pico.
The new Pico is a low cost, one box solution that is easy to install and requires very low maintenance. While it will suit all general applications, the system also has a built-in 35 litre reservoir, consumables that can be changed in seconds and many more efficient features....
New application note gives researchers insights and guidance on maximizing HDR-mediated insertion of short fragments in CRISPR genome editing
As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...
Melbourne-based melanoma researcher selected as the winner of ‘RNAscope ISH Get Hybridized’ giveaway, supporting cutting-edge research
Advanced Cell Diagnostics (ACD), a Bio-Techne brand, has announced the winner of its ‘RNAscope ISH Get Hybridized’ giveaway, designed to recognize and support groundbreaking research with RNAscope®in situ hybridization (ISH) technology. The winner, Dr. Andreas Behren, Group Leader in Cancer Immunobiology....
Dolomite Bio is delighted to announce the launch of the game-changing Nadia single cell platform, a groundbreaking system set to escalate scRNA-Seq to new heights, offering the fast-growing single cell research sector an innovative solution for a wide range of potential applications.
The Nadia instrument is a touchscreen-controlled, droplet-based microfluidic platform for single cell research, combining superior microfluidics, automated temperature control and gentle cell/bead agitation to offer a single compact instrument that delivers highly precise and reliable results.
The global market for chromatography instrumentation is expected to reach USD11.2 billion by the end of 2020, growing at a CAGR of around 6.3% from 2014 to 2021.
The rise in the investments in the field of R&D, the introduction of chromatography tests in drug approvals and advancements in the equipment of chromatography are some of the factors propelling the growth of the market....
Trial will analyze breath biomarkers to improve understanding of the treatment effects of a novel GSK pipeline drug candidate for COPD
Hichrom’s 2018 training courses
Experts from the biotechnology sector will report on the new developments in cell therapy. Sartorius has gained guest speakers Dr. Priscilla N. Kelly, editor of the journal Science, and Dr. Stefan W. Hell, the winner of the Nobel Prize in Chemistry 2014 and a professor at the Max Planck Institute for Biophysical Chemistry....
Understanding the causes of neurodegenerative diseases is a huge challenge. Outbreaks of BSE (commonly known as mad cow disease) and the rise of Alzheimer’s as a leading cause of death has meant that there is increasing pressure to find a cure....
The study, published today in Nature Communications, demonstrates the discovery of a distinct new worm protein which mimics a cytokine found in humans, known as transforming growth factor-beta (TGF-β). The newly-discovered protein switches off inflammation by...
Members of RGU’s School of Pharmacy and Life Sciences have held a number of events in recent weeks to engage with youngsters and imprint the scientific curiosity that can take them far in their future careers. It began with the celebration for National Pathology Week, where...
The development of biopharmaceuticals often requires lyophilized formulations to produce stable drug products, beginning with laboratory experiments followed by scale-up to larger lyophilizers. Limited supply and high cost of Active Pharmaceutical Ingredient (API) can present major challenges during formulation and process development....
Each calibrant or reference solution is supplied with a certificate of calibration detailing its calibrated or measured conductivity, as well as the associated uncertainty traced to ROMIL primary silver. PrimAg® is the clear choice when traceability is crucial....
Sphere Fluidics, a company providing single cell analysis systems underpinned by its patented picodroplet technology, and Geneva Biotech, an EMBL spin-out developing world-class viral and non-viral DNA delivery systems, have received a €1.6 million grant from Eurostars....
The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen....
The two parties signed a corresponding cooperation agreement last week in Berlin. The focus of the two partners’ future research efforts will be on the development of new devices and applications for element determination. In this connection, the teams will work jointly on the further development...
Professor Dawson brings a wealth of experience in the translation of cancer epigenetics research to clinical practice. The appointment further strengthens CEGX’s panel of opinion leaders providing expert advice across the Company’s key focus areas of epigenetics, oncology, liquid biopsy, diagnostic and therapeutic development....
Pyrazoles are an important and well represented chemotype in drug discovery displaying wide ranging biological actions that include analgesic, anti-inflammatory, antipyretic, tranquilizing, muscle relaxing, anticonvulsant, antidiabetic and antibacterial activities....
University and MRC researchers have developed a new platform for assessing anti-cancer drug efficacy in lung cancer that is more reflective of patient response than previously used model systems. The platform relies on the derivation of ‘explants’ from tumour tissue obtained fresh from surgery....
The first area of focus is that of Astell’s advanced colour touchscreen controller, with a selection of seventeen video tutorials available to explain common functions and setting adjustments, making it easy for owners of Astell sterilizers to find the perfect setup. Each clip provides a walk-through of steps....
By looking at a combination of specific proteins rather than at a single blood protein alone, substantially more patients with colorectal cancer and advanced adenomas could be detected. The study describing these findings, conducted by researchers from the Netherlands Cancer Institute and VU University Medical Center....
The new Pico is a low cost, one box solution that is easy to install and requires very low maintenance. While it will suit all general applications, the system also has a built-in 35 litre reservoir, consumables that can be changed in seconds and many more efficient features....
As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...
Advanced Cell Diagnostics (ACD), a Bio-Techne brand, has announced the winner of its ‘RNAscope ISH Get Hybridized’ giveaway, designed to recognize and support groundbreaking research with RNAscope® in situ hybridization (ISH) technology. The winner, Dr. Andreas Behren, Group Leader in Cancer Immunobiology....
The Nadia instrument is a touchscreen-controlled, droplet-based microfluidic platform for single cell research, combining superior microfluidics, automated temperature control and gentle cell/bead agitation to offer a single compact instrument that delivers highly precise and reliable results.
The new Edit-R CRISPRa offering provides researchers interested in gain-of-function studies with a powerful and easy-to-use two-component system for drug discovery, disease modeling, or pathway analysis....
The rise in the investments in the field of R&D, the introduction of chromatography tests in drug approvals and advancements in the equipment of chromatography are some of the factors propelling the growth of the market....